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Journal Articles

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Free
Greta De Jong, Sophie E Levie, Remko Schotte, PhD, Wouter Pos, PhD, Daniel Go, Etsuko Yasuda, Madalina Cercel, Susan E van Hal-van Veen, Esmay Frankin, Anikó Szabó, MD, Julien Villaudy, PhD, Pauline M van Helden, PhD, Hans van Eenennaam, PhD, Hergen Spits, PhD, Anita W Rijneveld, MD PhD, Mette D Hazenberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4461.
https://doi.org/10.1182/blood-2019-127894
Published: 2019
Journal Articles

Anti-CD20 Therapy Reliance on Antibody-Dependent Cellular Phagocytosis Affects Combination Drug Choice

Free
Charles C. Chu, PhD, Jonathan J. Pinney, MS, Karl R. VanDerMeid, BS, Raquel Izumi, PhD, Veerendra Munugalavadla, PhD, Paul M. Barr, MD, Michael Rusty Elliott, PhD, Clive S Zent, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 682.
https://doi.org/10.1182/blood-2019-124901
Published: 2019
Journal Articles

Risk-Adapted, Ofatumumab-Based Chemoimmunotherapy and Maintenance in Treatment-Naïve CLL: A Phase II Study

Free
Sanjal Desai, MD, Dennis Drinkwater, Clifton Craig Mo, MD, Mohammed ZH Farooqui, Susan Soto, Janet Valdez, Erika M Gaglione, Xin Tian, Pia Nierman, Jennifer Lotter, PA-C, Gerald Marti, Cydney Nichols, BS, Alankrita Taneja, MD, Sarah E. M. Herman, PhD, Irina Maric, MD MSci, Laura M Wake, MD, Maryalice Stetler-Stevenson, MD PhD, Constance M. Yuan, MD PhD, Tom Hughes, Pharm.D., Margaret A. Lindorfer, Ronald P. Taylor, Adrian Wiestner, MD PhD, Inhye E Ahn, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5474.
https://doi.org/10.1182/blood-2019-126698
Published: 2019
Journal Articles

Innate Immune Signal-Regulated Hematopoiesis

Free
Hitoshi Takizawa, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-1.
https://doi.org/10.1182/blood-2019-121288
Published: 2019
Journal Articles

From Graft-Versus-Host Disease to Lymphoma Pathogenesis: Emerging Roles for Stromal Notch Ligands in Hematology

Free
Ivan Maillard, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-47.
https://doi.org/10.1182/blood-2019-121067
Published: 2019
Journal Articles

Dynamic Immune Modulation Seen By Single Cell RNA-Sequencing of Serial Lymphoma Biopsies in Patients Undergoing in Situ Vaccination

Free
Tanaya Shree, MD PhD, Sarah Haebe, MD, Anuja Sathe, PhD, Grady Day, HoJoon Lee, PhD, Debra K. Czerwinski, BA, Susan Grimes, BSc, Hanlee Ji, MD, Ronald Levy, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1479.
https://doi.org/10.1182/blood-2019-131684
Published: 2019
Journal Articles

Immunophenotyping and Function of Peripheral Blood Mononuclear Cells in Patients Undergoing Unrelated Allogeneic Transplantation with Post-Transplantation Cyclophosphamide in Combination with ATG Anti-Graft Versus Host Disease Prophylaxis

Free
Katia Beider, Valeria Voevoda, Noga Shem-Tov, MD, Ronit Yerushalmi, MD, Ivetta Danilesko, MD, Ania Hava Grushchenko-Polaq, Olivia Devillers, Idit Wolf, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Arnon Nagler, MD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1989.
https://doi.org/10.1182/blood-2019-129619
Published: 2019
Journal Articles

Blinatumomab-Induced T Cell Activation at Single Cell Transcriptome Resolution

Free
Hong Yin, MD PhD, Yi Huo, PhD, Zhen Sheng, PhD, Chi-Ming Li, PhD, Daniel C Ellwanger, PhD, Daniel Lu, PhD, Oliver Homann, PhD, Songli Wang, MD PhD, Ruibao Ren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3886.
https://doi.org/10.1182/blood-2019-124636
Published: 2019
Journal Articles

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

Free
Anilkumar Gopalakrishnapillai, PhD, Colin Correnti, PhD, Anne Kisielewski, BS, Allison Kaeding, MD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3925.
https://doi.org/10.1182/blood-2019-130941
Published: 2019
Journal Articles

Functional Characterization of Gamma Delta T Cells and Allogeneic Activated NK Cells As Effector Cells for Tafasitamab (MOR208)

Free
Jung Hyun Her, Dominik Pretscher, Sungyoo Cho, Yu-Kyeong Hwang, Timm Hoeres, Rainer Boxhammer, Stefan Steidl, Maria Patra, Juergen Schanzer, Jan Endell
Journal: Blood
Blood (2019) 134 (Supplement_1): 3801.
https://doi.org/10.1182/blood-2019-128511
Published: 2019
Journal Articles

Latent Membrane Protein 1 Contributes to Deficient Cellular Immunity in NKTCL Patients

Free
Xiaoyan Feng, Yue Song, Zhaoming Li, MD PhD, Xudong Zhang, Lugui Qiu, MD PhD, Mingzhi Zhang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3969.
https://doi.org/10.1182/blood-2019-128622
Published: 2019
Journal Articles

Mechanistic Characterization of Tafasitamab-Mediated Antibody-Dependent Cellular Phagocytosis Alone or in Combination with Lenalidomide

Free
Dimitrios Mougiakakos, MD, Simon Voelkl, PhD, Christian Bach, Andrej Stoll, Katrin Bitterer, Fabian Beier, MD, Jan Endell, Rainer Boxhammer, Jörg Thomas Bittenbring, MD, Andreas Mackensen, MD, Heiko Bruns, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4064.
https://doi.org/10.1182/blood-2019-124886
Published: 2019
Journal Articles

Targeting DHODH with AG-636 Induces Apoptosis and Differentiation and Inhibits Mitochondrial Function in AML, Translating into Anti-Tumor Efficacy in Vitro and i n Vivo

Free
Zhihong Zeng, Natalia Baran, PhDMD, Sergej Konoplev, Antonio Cavazos, Qi Zhang, Vinitha Mary Kuruvilla, MSc, Philip Lorenzi, Hagop M. Kantarjian, MD, Michael Andreeff, MD PhD, Courtney D. DiNardo, MDMSc, Joshua Murtie, Danielle Ulanet, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3911.
https://doi.org/10.1182/blood-2019-125469
Published: 2019
Journal Articles

A Phase 1a/1b Trial of ST-001, a Fenretinide Phospholipid Suspension for 4-Hour Intravenous Infusion in Relapsed/Refractory T-Cell Non-Hodgkin's Lymphoma

Free
Ayad Al-Katib, MD, Timothy M. Kuzel, MD, Ralph Parchment, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4041.
https://doi.org/10.1182/blood-2019-127278
Published: 2019
Journal Articles

BrUOG 345: Fractionated Gemtuzumab Ozogamicin Followed By Non-Engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia

Free
Adam Zayac, MD, Pamela C Egan, MD, Thomas A Ollila, MD, Adam J Olszewski, MD, Peter Barth, MD, Matthew I. Quesenberry, MD, James Butera, MD, Loren D. Fast, PhD, Rabin Niroula, MBBS, Peter J. Quesenberry, MD, John L Reagan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4460.
https://doi.org/10.1182/blood-2019-123789
Published: 2019
Journal Articles

Equate, a Phase 1b/2 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of a Novel Targeted Anti-CD6 Therapy, Itolizumab, in Subjects with Newly Diagnosed Acute Graft Versus Host Disease

Free
John Koreth, MBBS, DPhil, Saurabh Chhabra, MD, Joseph Pidala, MD, Thomas C. Shea, MD, Madan Jagasia, MBBS, MS, MMHC, Edmund K. Waller, PhDMD, Ryotaro Nakamura, MD, Marco Mielcarek, MD, George L. Chen, MD, Gabrielle Meyers, MD, Daanish Hoda, MD, Betty K. Hamilton, MD, Cherie Tracy Ng, PhD MPH, Mark Sonnemann, Susan Light, MD, Nuwan Nanayakkara, PhD, David Essayan, MD, Joel Rothman, BS, Stephen Connelly, PhD MBA, Krishna Polu, MD, Leslie Kean, MD PhD, Jerome Ritz, MD, Robert J. Soiffer, MD, Corey Cutler, MD MPH, FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 4516.
https://doi.org/10.1182/blood-2019-127325
Published: 2019
Journal Articles

Restoring Innate and Adaptive Immune Repertoire in Multiple Myeloma for Therapeutic Application

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Rafael Alonso Fernández, MD, Laetitia Pierre-Louis, Rao Prabhala, Yan Xu, MD, Joaquin Martinez-Lopez, MD PhD, Takahiro Miyazaki, Mehmet Kemal Samur, PhD, Loui Madakamutil, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4398.
https://doi.org/10.1182/blood-2019-128767
Published: 2019
Journal Articles

Comparing Gradings of Immune Effector Cells Toxicities: Application of Astct Consensus Grading System and Implications for Clinical Management

Free
Martina Pennisi, Tania Jain, MD, Elena Mead, MD, Bianca Santomasso, MD PhD, Mari Lynne Silverberg, Yakup Batlevi, PhD, Roni Shouval, Molly A. Maloy, MS, Sean M. Devlin, PhD, Connie Lee Batlevi, MD PhD, Renier J. Brentjens, MD PhD, Parastoo B. Dahi, MD, Claudia Diamonte, RN, Jessica Flynn, BS, Sergio A Giralt, MD, Elizabeth Halton, NP-BC AOCNP, Maria Lia Palomba, MD, Miriam Sanchez-Escamilla, MD, Craig S. Sauter, MD, Michael Scordo, MD, Gunjan L. Shah, MD, Jae H. Park, MD, Miguel-Angel Perales, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4458.
https://doi.org/10.1182/blood-2019-126022
Published: 2019
Journal Articles

Genomic Profiles and Subset Characterization of CD8 + terminally Differentiated Effector Memory (T EMRA ) Cells from Cancer Patients

Free
Deok-Hwan Yang, MD PhD, Jae-Sook Ahn, Seo-Yeon Ahn, MD, Sung-Hoon Jung, MD, Je-Jung Lee, MD PhD, Hyeoung-Joon Kim, MD PhD, Young Rok Do, PhDMD, Sang Yun Song, MD PhD, Ga-Young Song, Hyeong Jong Kim, MD, Theresa Kim
Journal: Blood
Blood (2019) 134 (Supplement_1): 2329.
https://doi.org/10.1182/blood-2019-126533
Published: 2019
Journal Articles

Immune Phenotyping of Cytotoxic T-Cells Reveals a Novel Population of TIM3 Expressing Cells That Lack PD1 and Are Associated with Good Outcomes in Marginal Zone Lymphoma

Free
Theodora Anagnostou, MD, Zhi-Zhang Yang, MD, Hyojin Kim, PhD, Shahrzad Jalali, PhD, Jose C Villasboas, Hongyan Wu, PhD, Tammy Price-Troska, BS, Anne J Novak, PhD, Stephen M Ansell, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2790.
https://doi.org/10.1182/blood-2019-127757
Published: 2019