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Journal Articles

HIF2 keeps paces in tight hypoxic spaces

Sean P. Colgan

Blood (2021) 137 (24): 3323–3324.

https://doi.org/10.1182/blood.2021011009

Published: 2021

Journal Articles

HIF2α is a direct regulator of neutrophil motility

Sundary Sormendi, Mathieu Deygas, Anupam Sinha, Mathilde Bernard, Anja Krüger, Ioannis Kourtzelis, Gregoire Le Lay, Pablo J. Sáez, Michael Gerlach, Kristin Franke, Ana Meneses, Martin Kräter, Alessandra Palladini, Jochen Guck, Ünal Coskun, Triantafyllos Chavakis, Pablo Vargas, Ben Wielockx

Blood (2021) 137 (24): 3416–3427.

https://doi.org/10.1182/blood.2020007505

Published: 2021

Includes: Supplemental data

Journal Articles

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

Manik C. Ghosh, De-Liang Zhang, Wade H. Ollivierre, Audrey Noguchi, Danielle A. Springer, W. Marston Linehan, Tracey A. Rouault

Blood (2021) 137 (18): 2509–2519.

https://doi.org/10.1182/blood.2020009138

Published: 2021

Includes: Supplemental data

Journal Articles

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Shinichi Ishii, Tomohide Suzuki, Kanako Wakahashi, Noboru Asada, Yuko Kawano, Hiroki Kawano, Akiko Sada, Kentaro Minagawa, Yukio Nakamura, Seiya Mizuno, Satoru Takahashi, Toshimitsu Matsui, Yoshio Katayama

Blood (2021) 137 (11): 1457–1467.

https://doi.org/10.1182/blood.2020007172

Published: 2021

Includes: Supplemental data

Journal Articles

Sickle marrow: double, double toil and trouble

Mark C. Walters

Blood (2020) 135 (23): 2017–2018.

https://doi.org/10.1182/blood.2020005114

Published: 2020

Journal Articles

2'-O-Methoxyethyl Splice-Switching Oligos to Reverse Splicing from IVS2-745 β-Thalassemia Patient Cells: A Foundation for Potential Therapies

Blood (2019) 134 (Supplement_1): 2244.

https://doi.org/10.1182/blood-2019-127017

Published: 2019

Journal Articles

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Zachary C. Murphy, PhD, Kathleen E. McGrath, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2216.

https://doi.org/10.1182/blood-2019-127229

Published: 2019

Journal Articles

Establishment of a Spontaneous Stromal Microenvironment from Cord Blood Supports Human Dynamic Erythropoietic Temporal Maturation in Long-Term Serum- and Cytokine-Free 3D Cultures and Reveals a Distinct CD44 hi Population

Susana Brito Dos Santos, MSc PhD, Athanasios Mantalaris, PhD, Nicki Panoskaltsis, MD PhD

Blood (2019) 134 (Supplement_1): 2219.

https://doi.org/10.1182/blood-2019-131085

Published: 2019

Journal Articles

Glucose Metabolism in Sickle Cell Disease

Taif Hassan, Binal N. Shah, Xu Zhang, PhD, Victor R Gordeuk, MD

Blood (2019) 134 (Supplement_1): 4830.

https://doi.org/10.1182/blood-2019-131485

Published: 2019

Journal Articles

Thrombopoietin Has Protective Effect in Neonatal Hypoxia-Ischemia Rat Model

Liang Li, PhD, Liuming Yang, Hongwu Xin, Beng H Chong, MBBS, PhD, Mo Yang, MD

Blood (2019) 134 (Supplement_1): 4898.

https://doi.org/10.1182/blood-2019-131575

Published: 2019

Journal Articles

Association of Endothelial Biomarkers with Cerebral MRI Perfusion Analysis in Patients with Sickle Cell Disease

Liza Afzali-Hashemi, Lena Vaclavu, PhD, Erfan Nur, MD PhD, Aart J Nederveen, PhD, Bart J. Biemond, MD PhD

Blood (2019) 134 (Supplement_1): 1000.

https://doi.org/10.1182/blood-2019-124688

Published: 2019

Journal Articles

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Samuel Lessard, PhD, Pauline Rimmele, PhD, Hui Ling, PhD, Kevin Moran, MSc, Benjamin Vieira, BS, Yi-Dong Lin, PhD, Vu Hong, PhD, Andreas Reik, PhD, Denny Dang, Naoya Uchida, MD, John F. Tisdale, MD, Pablo Rendo, MD, Ahmed Daak, PhD, Alexandra Hicks, PhD

Blood (2019) 134 (Supplement_1): 974.

https://doi.org/10.1182/blood-2019-126048

Published: 2019

Journal Articles

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Tirthadipa Pradhan, Prithu Sundd, PhD, Satdarshan Pal Monga, Mark T Gladwin, MD, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 958.

https://doi.org/10.1182/blood-2019-131921

Published: 2019

Journal Articles

High Levels of Peripheral Vasoconstriction Detected By Polysomnography Predict More Acute Severe Pain Episodes in Children with Sickle Cell Anemia

Patjanaporn Chalacheva, PhD, Yunhua Ji, MS, Carol L. Rosen, MD, Michael R. DeBaun, MDMPH, Michael C.K. Khoo, PhD, Thomas Coates, MD

Blood (2019) 134 (Supplement_1): 894.

https://doi.org/10.1182/blood-2019-121944

Published: 2019

Journal Articles

Monitoring Sickle Cell Disease Using Spectral-Domain Optic Coherence Tomography in Pediatric Patients

Jing Jin, MD PhD, Robin E Miller, MD

Blood (2019) 134 (Supplement_1): 994.

https://doi.org/10.1182/blood-2019-123138

Published: 2019

Journal Articles

KTE-X19, an Anti-CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy, in Patients (Pts) With Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Results of the Phase 2 ZUMA-2 Study

Blood (2019) 134 (Supplement_1): 754.

https://doi.org/10.1182/blood-2019-126064

Published: 2019

Journal Articles

Roxadustat (FG4592; ASP1517; AZD9941) in the Treatment of Anemia in Patients with Lower Risk Myelodysplastic Syndrome (LR-MDS) and Low Red Blood Cell (RBC) Transfusion Burden (LTB)

David H. Henry, MD, John Glaspy, MD MPH, Rosemary Anne Harrup, MBBS, FRACP, FRCPA, Moshe Mittelman, MD, Amy Zhou, MD, Charles Bradley, PhD, Gopal Saha, MD, Pamela Bartels, Leong Robert, Kin-Hung P Yu, MD

Blood (2019) 134 (Supplement_1): 843.

https://doi.org/10.1182/blood-2019-128714

Published: 2019

Journal Articles

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, MD, Hui Zhang, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Liang Zhang, MD PhD, Krystle Nomie, PhD, Michael L. Wang, MD

Blood (2019) 134 (Supplement_1): 1506.

https://doi.org/10.1182/blood-2019-126738

Published: 2019

Journal Articles

Severity Classification for Sickle Cell Disease: A RAND/UCLA Modified Delphi Panel

Nirmish Shah, David Beenhouwer, Michael S Broder, MD MSHS, Lanetta Bronte-Hall, Laura De Castro, MD MHSc, Sarah N Gibbs, Victor R Gordeuk, MD, Julie Kanter, MD, Elizabeth S Klings, MD, Thokozeni Lipato, MD, Deepa Manwani, MD, Brigid Scullin, Irina Yermilov, Wally R Smith, MD

Blood (2019) 134 (Supplement_1): 415.

https://doi.org/10.1182/blood-2019-121556

Published: 2019

Journal Articles

Efficacy and Safety of Sevuparin, a Novel Non-Anti-Coagulant Heparinoid, in Patients with Acute Painful Vaso-Occlusive Crisis; A Global, Multicenter Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial (TVOC01)

Bart J. Biemond, MD PhD, Anil Tombak, MD, Yurdanur Kilinc, MD, Murtadha Al-Khabori, MD, Miguel R. Abboud, MD, Mohammed Nafea, MD, Adlette Inati, MD, Yasser Ahmed Mohamed Soliman Wali, MD, Jens Kristensen, MD PhD, Ellen Donnelly, PhD, John Ohd, MD PhD

Blood (2019) 134 (Supplement_1): 614.

https://doi.org/10.1182/blood-2019-124653

Published: 2019

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HIF2 keeps paces in tight hypoxic spaces

HIF2α is a direct regulator of neutrophil motility

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Sickle marrow: double, double toil and trouble

2'-O-Methoxyethyl Splice-Switching Oligos to Reverse Splicing from IVS2-745 β-Thalassemia Patient Cells: A Foundation for Potential Therapies

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Establishment of a Spontaneous Stromal Microenvironment from Cord Blood Supports Human Dynamic Erythropoietic Temporal Maturation in Long-Term Serum- and Cytokine-Free 3D Cultures and Reveals a Distinct CD44 hi Population

Glucose Metabolism in Sickle Cell Disease

Thrombopoietin Has Protective Effect in Neonatal Hypoxia-Ischemia Rat Model

Association of Endothelial Biomarkers with Cerebral MRI Perfusion Analysis in Patients with Sickle Cell Disease

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

High Levels of Peripheral Vasoconstriction Detected By Polysomnography Predict More Acute Severe Pain Episodes in Children with Sickle Cell Anemia

Monitoring Sickle Cell Disease Using Spectral-Domain Optic Coherence Tomography in Pediatric Patients

KTE-X19, an Anti-CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy, in Patients (Pts) With Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Results of the Phase 2 ZUMA-2 Study

Roxadustat (FG4592; ASP1517; AZD9941) in the Treatment of Anemia in Patients with Lower Risk Myelodysplastic Syndrome (LR-MDS) and Low Red Blood Cell (RBC) Transfusion Burden (LTB)

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Severity Classification for Sickle Cell Disease: A RAND/UCLA Modified Delphi Panel

Efficacy and Safety of Sevuparin, a Novel Non-Anti-Coagulant Heparinoid, in Patients with Acute Painful Vaso-Occlusive Crisis; A Global, Multicenter Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial (TVOC01)

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