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Journal Articles

ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes

Rafail Nikolaos Tasakis, MSc, BSc, Alessandro Lagana, PhD, Violetta Leshchenko, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Jonathan J Keats, PhD, Daniel Auclair, Deepu Madduri, MD, Joshua Richter, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, F. Nina Papavasiliou, PhD, Samir Parekh, MD

Blood (2019) 134 (Supplement_1): 3092.

https://doi.org/10.1182/blood-2019-130669

Published: 2019

Journal Articles

Analysis of Molecular-Cellular Responses to Proteasome Inhibitors in Multiple Myeloma Patients; A Translational Approach of Proteasome Inhibitors In Vivo Effects from the Drosophila Experimental Model to Humans

Eleni-Dimitra Papanagnou, Tina Bagratuni, Efstathios Kastritis, Issidora Papassideri, Evangelos Terpos, MD, Meletios A. Dimopoulos, Ioannis P. Trougakos

Blood (2015) 126 (23): 3250.

https://doi.org/10.1182/blood.V126.23.3250.3250

Published: 2015

Journal Articles

Translating Findings of Proteasome Inhibitors Effects from the in Vivo Drosophila Experimental Model to Humans: The Paradigm of the Molecular-Cellular Responses to Bortezomib and Carfilzomib

Ioannis P. Trougakos, Eleni-Dimitra Papanagnou, Tina Bagratuni, Efstathios Kastritis, MD, Issidora S. Papassideri, Evangelos Terpos, Meletios A. Dimopoulos

Blood (2014) 124 (21): 4814.

https://doi.org/10.1182/blood.V124.21.4814.4814

Published: 2014

Journal Articles

Deficiency Of JAGN1 Causes Severe Congenital Neutropenia Associated With Defective Secretory Pathway and Aberrant Myeloid Cell Homeostasis

Blood (2013) 122 (21): 439.

https://doi.org/10.1182/blood.V122.21.439.439

Published: 2013

Journal Articles

The Novel Proteasome Inhibitors Carfilzomib and Oprozomib Induce Milder Degenerative Effects Compared To Bortezomib When Administered Via Oral Feeding In An In Vivo Drosophila Experimental Model: A Biological Platform To Evaluate Safety/Efficacy Of Proteasome Inhibitors

Evangelos Terpos, Eleni N. Tsakiri, Efstathios Kastritis, Tina Bagratuni, Vassilis G. Gorgoulis, Ioannis P. Trougakos, Meletios A. Dimopoulos, MD

Blood (2013) 122 (21): 1930.

https://doi.org/10.1182/blood.V122.21.1930.1930

Published: 2013

Journal Articles

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia

Megan E. McNerney, Christopher D. Brown, Xiaoyue Wang, Elizabeth T. Bartom, Subhradip Karmakar, Chaitanya Bandlamudi, Shan Yu, Jinkyung Ko, Barry P. Sandall, Thomas Stricker, John Anastasi, Robert L. Grossman, John M. Cunningham, Michelle M. Le Beau, Kevin P. White

Blood (2013) 121 (6): 975–983.

https://doi.org/10.1182/blood-2012-04-426965

Published: 2013

Includes: Supplemental data

Journal Articles

Absence of Spred, a Negative Regulator of Tyrosine Kinase Activity, in Acute Myeloid Leukemia Patients

Valentina Rosso, PhD, Cristina Panuzzo, PhD, Enrico Bracco, PhD, Sonia Carturan, PhD, Valentina Campia, PhD, Alessandra Favole, PhD, Elisabetta Signorino, PhD, Pimjai Niparuk, MD, Chiara Calabrese, PhD, Luciana De Luca, MD, Antonella Caivano, Annalisa Morano, Francesco Frassoni, Giuseppe Saglio, MD, Daniela Cilloni, MD

Blood (2012) 120 (21): 4616.

https://doi.org/10.1182/blood.V120.21.4616.4616

Published: 2012

Journal Articles

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

Yujie Wen, Mary J Elliott, Yiming Huang, Deborah R Corbin, Yoshinori Fukui, Mariusz Z Ratajczak, Suzanne T Ildstad

Blood (2011) 118 (21): 142.

https://doi.org/10.1182/blood.V118.21.142.142

Published: 2011

Journal Articles

TRIB2 Gene Overexpression Is Associated with Adult Minimally Differentiated Acute Myeloid Leukemia

Crescenzio Francesco Minervini, Valentina Buttiglione, Nicoletta Coccaro, Luciana Impera, Luisa Anelli, Antonella Zagaria, Paola Casieri, Angela Minervini, Giuseppina Tota, Francesco Albano, Giorgina Specchia

Blood (2011) 118 (21): 4628.

https://doi.org/10.1182/blood.V118.21.4628.4628

Published: 2011

Journal Articles

Disabled Gene Is Involved in CML Progression and Its Expression Level at Diagnosis Can Predict Major Molecular Response (MMR) to Imatinib Therapy.

Daniela Cilloni, MD, PhD, Francesca Arruga, PhD, Francesca Messa, PhD, Monica Pradotto, PhD, Enrico Bracco, PhD, Sonia Carturan, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Antonia Rotolo, MD, Elisabetta Greco, MD, Ilaria Iacobucci, PhD, Roberto Bernardoni, Fabrizio Pane, MD, Thea Kalebic, MD, Giovanni Martinelli, Michele Baccarani, MD, Giuseppe Saglio, MD

Blood (2009) 114 (22): 3964.

https://doi.org/10.1182/blood.V114.22.3964.3964

Published: 2009

Journal Articles

Genome-Wide Screening for Dominant Modifiers in Drosophila Identified New Cluster of Genes Involved in BCR-ABL Signalling and CML Progression.

Francesca Messa, PhD, Monica Pradotto, PhD, Francesca Arruga, PhD, Roberto Bernardoni, PhD, Enrico Bracco, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Sonia Carturan, PhD, Elisabetta Signorino, PhD, Elisabetta Greco, MD, Antonia Rotolo, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Giuseppe Saglio, MD, Daniela Cilloni, MD, PhD

Blood (2009) 114 (22): 2186.

https://doi.org/10.1182/blood.V114.22.2186.2186

Published: 2009

Journal Articles

Identification of Rab5 as a Gene Involved in Chronic Myeloid Leukemia (CML) Progression.

Daniela Cilloni, MD, PhD, Monica Pradotto, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Sonia Carturan, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Antonia Rotolo, MD, Elisabetta Greco, MD, Ilaria Iacobucci, PhD, Thea Kalebic, MD, Roberto Bernardoni, Fabrizio Pane, MD, Giovanni Martinelli, MD, Michele Baccarani, M.D., Giuseppe Saglio, MD

Blood (2009) 114 (22): 3470.

https://doi.org/10.1182/blood.V114.22.3470.3470

Published: 2009

Journal Articles

Imatinib Induced Re-Activation of FoxO3 Transcription Factor in CML Is Responsible for the Induction of a Quiescent Status of CD34 Leukaemic Progenitor Cells.

Daniela Cilloni, MD, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Roberto Bernardoni, PhD, Sonia Carturan, PhD, Marisa Pautasso, MD, Emanuela Messa, MD, Alessandro Morotti, MD, Monica Pradotto, PhD, Ilaria Iacobucci, Thea Kalebic, MD, Giovanni Martinelli, MD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1090.

https://doi.org/10.1182/blood.V112.11.1090.1090

Published: 2008

Journal Articles

Identification of Genes Sustaining Bcr-Abl Oncogenic Signalling and CML Progression through a Genetic Tool Based on Human Bcr-Abl Transgenic Drosophila Melanogaster.

Daniela Cilloni, Francesca Messa, PhD, Roberto Bernardoni, PhD, Francesca Arruga, PhD, Monica Pradotto, PhD, Enrico Bracco, PhD, Cristina Panuzzo, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Ilaria Iacobucci, Thea Kalebic, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1091.

https://doi.org/10.1182/blood.V112.11.1091.1091

Published: 2008

Journal Articles

A Functional Screen Identifies Polarity Genes Implicated in HSC Fate

Stephen Ting, MD, PhD, Eric Deneault, Melanie Frechette, Jalila Chagraoui, Guy Sauvageau

Blood (2008) 112 (11): 732.

https://doi.org/10.1182/blood.V112.11.732.732

Published: 2008

Journal Articles

Kpm/Lats2 of the Hippo Pathway Is Linked to Chemo-Sensitivity of Leukemic Cells.

Masahiro Kawahara, Toshiyuki Hori, Kazuhisa Chonabayashi, Tsutomu Oka, Marius Sudol, Takashi Uchiyama

Blood (2008) 112 (11): 1797.

https://doi.org/10.1182/blood.V112.11.1797.1797

Published: 2008

Journal Articles

Development of a Genetic Tool Based on BCR-ABL Transgenic Drosophila Melanogaster for Identification of Genes Involved in CML Progression and Drug Testing.

Daniela Cilloni, MD, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Paolo Nicoli, MD, Emanuela Messa, MD, Stefano Ulisciani, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Thea Kalebic, MD, Michele Baccarani, MD, Fabian Feiguin, MD, PhD, Giuseppe Saglio, MD

Blood (2007) 110 (11): 468.

https://doi.org/10.1182/blood.V110.11.468.468

Published: 2007

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ADAR1 Drives Disease Progression in Multiple Myeloma By Acting Both As an RNA Editor of Specific Transcripts and As a DNA Mutator of Their Cognate Genes

Analysis of Molecular-Cellular Responses to Proteasome Inhibitors in Multiple Myeloma Patients; A Translational Approach of Proteasome Inhibitors In Vivo Effects from the Drosophila Experimental Model to Humans

Translating Findings of Proteasome Inhibitors Effects from the in Vivo Drosophila Experimental Model to Humans: The Paradigm of the Molecular-Cellular Responses to Bortezomib and Carfilzomib

Deficiency Of JAGN1 Causes Severe Congenital Neutropenia Associated With Defective Secretory Pathway and Aberrant Myeloid Cell Homeostasis

The Novel Proteasome Inhibitors Carfilzomib and Oprozomib Induce Milder Degenerative Effects Compared To Bortezomib When Administered Via Oral Feeding In An In Vivo Drosophila Experimental Model: A Biological Platform To Evaluate Safety/Efficacy Of Proteasome Inhibitors

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia

Absence of Spred, a Negative Regulator of Tyrosine Kinase Activity, in Acute Myeloid Leukemia Patients

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

TRIB2 Gene Overexpression Is Associated with Adult Minimally Differentiated Acute Myeloid Leukemia

Disabled Gene Is Involved in CML Progression and Its Expression Level at Diagnosis Can Predict Major Molecular Response (MMR) to Imatinib Therapy.

Genome-Wide Screening for Dominant Modifiers in Drosophila Identified New Cluster of Genes Involved in BCR-ABL Signalling and CML Progression.

Identification of Rab5 as a Gene Involved in Chronic Myeloid Leukemia (CML) Progression.

Imatinib Induced Re-Activation of FoxO3 Transcription Factor in CML Is Responsible for the Induction of a Quiescent Status of CD34 Leukaemic Progenitor Cells.

Identification of Genes Sustaining Bcr-Abl Oncogenic Signalling and CML Progression through a Genetic Tool Based on Human Bcr-Abl Transgenic Drosophila Melanogaster.

A Functional Screen Identifies Polarity Genes Implicated in HSC Fate

Kpm/Lats2 of the Hippo Pathway Is Linked to Chemo-Sensitivity of Leukemic Cells.

Development of a Genetic Tool Based on BCR-ABL Transgenic Drosophila Melanogaster for Identification of Genes Involved in CML Progression and Drug Testing.

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