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Journal Articles

DARTs point the way forward in AML

Free
Clinical Trials & Observations
Saar Gill
Journal: Blood
Blood (2021) 137 (6): 720–721.
https://doi.org/10.1182/blood.2020009020
Published: 2021
Journal Articles

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

Free
CME
Elise Chapiro, Elodie Pramil, M’boyba Diop, Damien Roos-Weil, Clémentine Dillard, Clémentine Gabillaud, Karim Maloum, Catherine Settegrana, Lucile Baseggio, Jean-François Lesesve, Mélanie Yon, Ludovic Jondreville, Claude Lesty, Frédéric Davi, Magali Le Garff-Tavernier, Nathalie Droin, Philippe Dessen, Caroline Algrin, Véronique Leblond, Jean Gabarre, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, Christine Lefebvre, Nathalie Nadal, Antoine Ittel, Stéphanie Struski, Marie-Agnès Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, Santos A. Susin, Olivier A. Bernard, Florence Nguyen-Khac
Journal: Blood
Blood (2019) 134 (21): 1821–1831.
https://doi.org/10.1182/blood.2019001187
Published: 2019
Includes: Supplemental data
Journal Articles

Integrated Transcriptomic and Genomic Sequencing Identifies Prognostic Constellations of Driver Mutations in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Free
Ilaria Iacobucci, PhD, Manja Meggendorfer, PhD, Niroshan Nadarajah, Stanley Pounds, PhD, Lei Shi, PhD, Chunxu Qu, PhD, Constance Baer, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Charles G. Mullighan, MBBS, MD, Torsten Haferlach, MD
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-4.
https://doi.org/10.1182/blood-2019-132746
Published: 2019
Journal Articles

Impact of Clinical Features, Cytogenetics, Genetic Mutations and Methylation of CDKN2B and DLC-1 Promoters on Treatment Response to Azacitidine

Free
Iván Martín, Alicia Serrano, Blanca Navarro, MD PhD, Eva Villamón, PhD, Marisa Calabuig, MD, Juan Carlos Hernandez Boluda, Javier F Chaves, PhD, María Isabel Orts, MD, Nuria Yagüe, Paula Amat, MD PhD, Fernando Domingo, Yoana Hernández, Paula Coll, Azahara Fuentes, Enrique Seda, Francisca García, Angeles Muñoz, Carlos Solano, MD PhD, Mar Tormo
Journal: Blood
Blood (2019) 134 (Supplement_1): 5412.
https://doi.org/10.1182/blood-2019-129019
Published: 2019
Journal Articles

Clinical and Genetic Features of Constitutional Partial Trisomy 8 Mosaicism (CT8M) Patients with Cytopenia

Free
Yuta Yamada, MD, Noriko Doki, MD PhD, Yuka Harada, MD PhD, Yuki Otsuka, MD, Ryosuke Konuma, MD, Hiroto Adachi, MD, Atsushi Wada, MD, Yuya Kishida, MD, Tatsuya Konishi, Akihito Nagata, Yuma Noguchi, MD, Atsushi Marumo, MD, Junichi Mukae, MD, Kyoko Inamoto, MD, Takashi Toya, MD PhD, Aiko Igarashi, MD, Yuho Najima, MD PhD, Takeshi Kobayashi, MD, Hiroshi Yoshihashi, Hironori Harada, MD PhD, Hisashi Sakamaki, MD PhD, Kazuteru Ohashi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5413.
https://doi.org/10.1182/blood-2019-129711
Published: 2019
Journal Articles

The Biological Inferences from the Ranking of SF3B1 Mutations in the Clonal Hierarchy of Myeloid Neoplasia

Free
Hassan Awada, Jibran Durrani, Ashwin Kishtagari, MBBS, Vera Adema, PhD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, Bartlomiej Przychodzen, Jack Khouri, MD, Heesun J. Rogers, MD PhD, Manja Meggendorfer, PhD, Anjali S. Advani, MD, Aziz Nazha, MD, Torsten Haferlach, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5411.
https://doi.org/10.1182/blood-2019-128965
Published: 2019
Journal Articles

Patient-Specific Risk Factors Independently Influence Survival in Myelodysplastic Syndromes in an Unbiased Review of EHR Records

Free
Travis Spaulding, MD, Nicholas Strayer, Andrew Sochacki, MD, Shannon Stockton, MD, Alexander Silver, Rodney Dixon Dorand, MD PhD, Siwei Zhang, PhD, Ya-Chen Lin, Yaomin Xu, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5440.
https://doi.org/10.1182/blood-2019-122400
Published: 2019
Journal Articles

Improved Treatment of Childhood ALL in Malaysia

Free
Hamidah Alias, MMed (Paed), Sie Chong Doris Lau, MMed (Paed), C-Khai Loh, MRCPCH, Christine J. Harrison, PhD FRCPath, Jeyanthy Eswaran, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5828.
https://doi.org/10.1182/blood-2019-129402
Published: 2019
Journal Articles

Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study

Free
Johannes B Goll, MS, R. Coleman Lindsley, MD PhD, William F. Hooper, MS, Rafael Bejar, MD PhD, Jason Walker, Robert Fulton, MS, Gregory A. Abel, MDMPH, Tareq Al Baghdadi, MD, H. Joachim Deeg, MD, Amy E. DeZern, MD, Benjamin Ebert, MD, Pearlie Epling-Burnette, PhD PharmD, James M. Foran, MD, Edward J. Gorak, DO,MBA,MS, Steven D. Gore, MD, Rami S. Komrokji, MD, Jane Jijun Liu, MD, Jaroslaw P. Maciejewski, MD PhD, Eric Padron, MD, Wael Saber, MD MS, Daniel T. Starczynowski, PhD, Myron Waclawiw, PhD, Nancy DiFronzo, PhD, Mikkael A. Sekeres, MD MS, Ling Zhang, MD, Matthew J. Walter, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4271.
https://doi.org/10.1182/blood-2019-126978
Published: 2019
Journal Articles

Chromosome Banding Analysis Versus Genomic Microarrays: A Comparison of Methods for Genomic Complexity Risk Stratification in Chronic Lymphocytic Leukemia Patients with Complex Karyotype

Free
Silvia Ramos Campoy, Anna Puiggros, PhD, Silvia Bea, PhD, Sandrine Bougeon, Maria Jose Larrayoz, PhD, Guillem Clot, Dolors Costa, MD, Gian Matteo Rigolin, MD, Margarita Ortega, Laura Blanco, Rosa Collado, MD, Rocio N Salgado, PhD, María-Dolores García-Malo, MD, Andrea Campeny, Alberto Valiente, Ferran Nadeu, BSc, MSc, Julio Delgado, Tycho Baumann, Idoya Ancín, Marco Antonio Moro García, Eva Gimeno, MD PhD, Carol Moreno, MD PhD, Francesc Bosch, MD PhD, Ana Ferrer, MD PhD, Gonzalo Blanco, PhD, Maria Jose Calasanz, PhD BSc, Antonio Cuneo, MD, Claudia Haferlach, MD, Jacqueline Schoumans, PhD, Blanca Espinet, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4287.
https://doi.org/10.1182/blood-2019-126557
Published: 2019
Journal Articles

Histone Modifications in Development and Malignancy

Free
Elisa Oricchio, DPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-49.
https://doi.org/10.1182/blood-2019-121289
Published: 2019
Journal Articles

The Detection of Minor Clones with Somatic KIT D816V Mutations Using Droplet Digital PCR in Pediatric De Novo AML: AML-05 Trial from the Japanese Pediatric Leukemia/Lymphoma Study Group

Free
Koji Sasaki, MD, Yuri Uchiyama, MD PhD, Junji Ikeda, Masahiro Yoshitomi, Yuko Shimosato-Wada, Mayu Tokumasu, Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kentaro Oki, MD PhD, Genki Yamato, MD PhD, Yusuke Hara, Akitoshi Kinoshita, MD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Souichi Adachi, MD PhD, Akio Tawa, MD PhD, Keizo Horibe, MD PhD, Naomichi Matsumoto, MD PhD, Shuichi Ito, MD PhD, Yasuhide Hayashi, MD PhD, Norio Shiba
Journal: Blood
Blood (2019) 134 (Supplement_1): 1419.
https://doi.org/10.1182/blood-2019-127656
Published: 2019
Journal Articles

Coexistence and Prognostic Significance of EVI1 Expression and Driver Mutations in KMT2A -Rearranged Acute Myeloid Leukemia

Free
Hidemasa Matsuo, PhD, Kenichi Yoshida, MD PhD, Kana Nakatani, Yasuhiko Kamikubo, MD, PhD, Daisuke Tomizawa, MD PhD, Takashi Taga, MD PhD, Nobutaka Kiyokawa, MD PhD, Seishi Ogawa, MD PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Souichi Adachi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1409.
https://doi.org/10.1182/blood-2019-124652
Published: 2019
Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Free
Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3735.
https://doi.org/10.1182/blood-2019-124774
Published: 2019
Journal Articles

Tolerability and Efficacy of Crenolanib and Cytarabine/Anthracycline Chemotherapy in Older Patients (Aged 61 to 75) with Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia (AML)

Free
Eunice S. Wang, MD, Elizabeth A. Griffiths, MD, Roland B. Walter, MD PhD MS, Martin S. Tallman, MD, Aaron D Goldberg, MD PhD, Boo Messahel, MD, Richard M. Stone, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3829.
https://doi.org/10.1182/blood-2019-130536
Published: 2019
Journal Articles

High TP53 Mutation Load Predicts Primary Refractory Mantle Cell Lymphoma

Free
Aleš Obr, MD PhD, Pavel Klener, Jr., Eva Kriegova, Dr, assoc prof, Zuzana Zemanova, PhD, Helena Urbankova, MSc, PhD, Andrea Jirkuvova, MD, Anna Petrackova, MSc, Barbora Cudova, Lenka Sedlarikova, MSc, VIT K Prochazka, MD, Tomas Papajik, MD prof, Marek Trneny, MD prof
Journal: Blood
Blood (2019) 134 (Supplement_1): 3995.
https://doi.org/10.1182/blood-2019-123812
Published: 2019
Journal Articles

Superior Pre-Clinical Efficacy of Novel Protac Based BET Degrader in a Large Acute Myeloid Leukemia Cohort

Free
Malathi Kandarpa, PhD, Luke F. Peterson, PhD, Harish Potu, PhD, Yihong Liu, Avery Polk, Shaomeng Wang, PhD, Moshe Talpaz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3936.
https://doi.org/10.1182/blood-2019-131759
Published: 2019
Journal Articles

Short Time to Treatment Is Associated with Inferior Survival in Newly Diagnosed Patients with Mantle Cell Lymphoma

Free
Narendranath Epperla, MDMS, Jeffrey M. Switchenko, PhD MS, Krithika Shanmugasundaram, MD, Subir Goyal, Oscar Calzada, BS, Michael C. Churnetski, Bhaskar Kolla, MBBS, Veronika Bachanova, MD PhD, James N. Gerson, MD, Stefan K. Barta, MD MRCP, MS, Max J. Gordon, MD, Alexey Danilov, MD PhD, Natalie S Grover, MD, Stephanie Mathews, MD, Madelyn Burkart, MD, Reem Karmali, MD, Yazeed Sawalha, MD, Brian T. Hill, MD, Nilanjan Ghosh, MD PhD, Steven I Park, MD, David A. Bond, MD, Talha Badar, MD, Kristie A. Blum, MD, Mehdi Hamadani, MD, Timothy S. Fenske, MD, Mary-Kate Malecek, MD, Peter Martin, FRCPC, MD MS, Jin Guo, MD, Brad S. Kahl, MD, Christopher R. Flowers, MD MS, Jonathon B. Cohen, MDMS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3997.
https://doi.org/10.1182/blood-2019-128632
Published: 2019
Journal Articles

Phase 3 Exploratory Analysis of Outcomes in Patients with Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Who Received Consolidation with CPX-351 Versus Conventional Chemotherapy

Free
Jonathan E. Kolitz, MD, Daniel H. Ryan, MD, Laura F. Newell, MD, Stephen A. Strickland, MD, Donna E. Hogge, MD PhD, Scott R. Solomon, MD, Gary J. Schiller, MD, Robert J. Ryan, MS, Stefan Faderl, MD, Jorge E. Cortes, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3856.
https://doi.org/10.1182/blood-2019-124553
Published: 2019
Journal Articles

Title: 12 Versus 8 Prophylactic Intrathecal (IT) Chemotherapy Administration Decrease Incidence of Central Nervous System (CNS) Relapse in Patients (pts) with Newly Diagnosed Philadelphia (Ph)-Positive Acute Lymphocytic Leukemia (ALL)

Free
Shilpa Paul, PharmD, Koji Sasaki, MD, J Michael Savoy, PharmD, Adam Dipippo, PharmD, Nadya Jammal, PharmD, Kayleigh Marx, PharmD, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Farhad Ravandi, MD, Hagop M. Kantarjian, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3810.
https://doi.org/10.1182/blood-2019-130284
Published: 2019