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Journal Articles

Hyperstable SGK1 steps out of AKT’s shadow

Franziska Gehringer, Alexey Ushmorov

Blood (2021) 138 (11): 917–918.

https://doi.org/10.1182/blood.2021012518

Published: 2021

Journal Articles

Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression

Vikas A. Gupta, Benjamin G. Barwick, Shannon M. Matulis, Ryosuke Shirasaki, David L. Jaye, Jonathan J. Keats, Benjamin Oberlton, Nisha S. Joseph, Craig C. Hofmeister, Leonard T. Heffner, Madhav V. Dhodapkar, Ajay K. Nooka, Sagar Lonial, Constantine S. Mitsiades, Jonathan L. Kaufman, Lawrence H. Boise

Blood (2021) 137 (26): 3604–3615.

https://doi.org/10.1182/blood.2020007899

Published: 2021

Includes: Supplemental data

Journal Articles

Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death

Ana Domostegui, Suresh Peddigari, Carol A. Mercer, Flavia Iannizzotto, Marta L. Rodriguez, Marta Garcia-Cajide, Virginia Amador, Sarah T. Diepstraten, Gemma L. Kelly, Ramón Salazar, Sara C. Kozma, Eric P. Kusnadi, Jian Kang, Antonio Gentilella, Richard B. Pearson, George Thomas, Joffrey Pelletier

Blood (2021) 137 (24): 3351–3364.

https://doi.org/10.1182/blood.2020007452

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas

Scott Boiko, Theresa Proia, Maryann San Martin, Gareth P. Gregory, Michelle Min Wu, Neeraj Aryal, Maureen Hattersley, Wenlin Shao, Jamal C. Saeh, Stephen E. Fawell, Ricky W. Johnstone, Lisa Drew, Justin Cidado

Blood (2021) 137 (21): 2947–2957.

https://doi.org/10.1182/blood.2020008528

Published: 2021

Includes: Supplemental data

Journal Articles

OBF1 and Oct factors control the germinal center transcriptional program

Shuang Song, Chun Cao, Mohamed-Amin Choukrallah, Fengyuan Tang, Gerhard Christofori, Hubertus Kohler, Fabian Wu, Barna D. Fodor, Mathias Frederiksen, Simon N. Willis, Jacob T. Jackson, Stephen L. Nutt, Stefan Dirnhofer, Michael B. Stadler, Patrick Matthias

Blood (2021) 137 (21): 2920–2934.

https://doi.org/10.1182/blood.2020010175

Published: 2021

Includes: Supplemental data

Journal Articles

CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1

Roger Belizaire, Sebastian H. J. Koochaki, Namrata D. Udeshi, Alexis Vedder, Lei Sun, Tanya Svinkina, Christina Hartigan, Marie McConkey, Veronica Kovalcik, Amanuel Bizuayehu, Caroline Stanclift, Monica Schenone, Steven A. Carr, Eric Padron, Benjamin L. Ebert

Blood (2021) 137 (16): 2209–2220.

https://doi.org/10.1182/blood.2020006528

Published: 2021

Includes: Supplemental data

Journal Articles

Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL

Lorena Fontan, Rebecca Goldstein, Gabriella Casalena, Matthew Durant, Matthew R. Teater, Jimmy Wilson, Jude Phillip, Min Xia, Shivem Shah, Ilkay Us, Himaly Shinglot, Ankur Singh, Giorgio Inghirami, Ari Melnick

Blood (2021) 137 (6): 788–800.

https://doi.org/10.1182/blood.2019004713

Published: 2021

Includes: Supplemental data

Journal Articles

BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells

Kimihito C. Kawabata, Hongliang Zong, Cem Meydan, Sarah Wyman, Bas J. Wouters, Mayumi Sugita, Srinjoy Goswami, Michael Albert, Winnie Yip, Gail J. Roboz, Zhengming Chen, Ruud Delwel, Martin Carroll, Christopher E. Mason, Ari Melnick, Monica L. Guzman

Blood (2021) 137 (6): 812–825.

https://doi.org/10.1182/blood.2019001745

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-2100

Tatsuro Watanabe, Satoshi Yamashita, Hiroshi Ureshino, Kazuharu Kamachi, Yuki Kurahashi, Yuki Fukuda-Kurahashi, Nao Yoshida, Naoko Hattori, Hideaki Nakamura, Akemi Sato, Atsushi Kawaguchi, Naoko Sueoka-Aragane, Kensuke Kojima, Seiji Okada, Toshikazu Ushijima, Shinya Kimura, Eisaburo Sueoka

Blood (2020) 136 (7): 871–884.

https://doi.org/10.1182/blood.2019003084

Published: 2020

Includes: Supplemental data

Journal Articles

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

Blood (2020) 136 (4): 468–479.

https://doi.org/10.1182/blood.2019004147

Published: 2020

Includes: Supplemental data

Journal Articles

A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

Kodandaram Pillarisetti, Suzanne Edavettal, Mark Mendonça, Yingzhe Li, Mark Tornetta, Alexander Babich, Nate Majewski, Matt Husovsky, Dara Reeves, Eileen Walsh, Diana Chin, Leopoldo Luistro, Jocelin Joseph, Gerald Chu, Kathryn Packman, Shoba Shetty, Yusri Elsayed, Ricardo Attar, François Gaudet

Blood (2020) 135 (15): 1232–1243.

https://doi.org/10.1182/blood.2019003342

Published: 2020

Includes: Supplemental data

Journal Articles

Tearing ATL apart to find HTLV’s sinister plans

Mark Y. Chiang

Blood (2020) 135 (12): 887–889.

https://doi.org/10.1182/blood.2020004998

Published: 2020

Journal Articles

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Yusuke Tarumoto, Shan Lin, Jinhua Wang, Joseph P. Milazzo, Yali Xu, Bin Lu, Zhaolin Yang, Yiliang Wei, Sofya Polyanskaya, Mark Wunderlich, Nathanael S. Gray, Kimberly Stegmaier, Christopher R. Vakoc

Blood (2020) 135 (1): 56–70.

https://doi.org/10.1182/blood.2019001576

Published: 2020

Includes: Supplemental data

Journal Articles

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

Sohaila Mohamed Khalil, Swagata Goswami, MSc, Xiaokui Mo, PhD MAS, Natarajan Muthusamy, DVM,PhD

Blood (2019) 134 (Supplement_1): 3977.

https://doi.org/10.1182/blood-2019-129224

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 3946.

https://doi.org/10.1182/blood-2019-130261

Published: 2019

Journal Articles

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Alessandra Di Grande, BSc, Sofie Piers, Pieter Van Vlierberghe, PhD, Triona Ni Chonghaile, PhD BSc

Blood (2019) 134 (Supplement_1): 3800.

https://doi.org/10.1182/blood-2019-127970

Published: 2019

Journal Articles

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

Taylor J Chen, BS, Ye Shen, PhD, Cory Seth Bridges, BS, Chun Shik Park, PhD, Jacob J. Junco, PhD, Karen R. Rabin, MD PhD, H. Daniel Lacorazza, PhD

Blood (2019) 134 (Supplement_1): 3889.

https://doi.org/10.1182/blood-2019-129127

Published: 2019

Journal Articles

The Clinical and Functional Relevance of the Transforming AKT E17K Mutation in T-ALL

Jordy C.G. Van Der Zwet, MD, Jessica G.C.A.M. Buijs-Gladdines, Izabela Mollova, BSc, Laura Graus, BSc, Frank L. Bos, PhD, Anne C. Rios, PhD, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 3804.

https://doi.org/10.1182/blood-2019-124669

Published: 2019

Journal Articles

Targeted Protein Degradation of BTK As a Unique Therapeutic Approach for B Cell Malignancies

Blood (2019) 134 (Supplement_1): 3805.

https://doi.org/10.1182/blood-2019-129262

Published: 2019

Journal Articles

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

Anilkumar Gopalakrishnapillai, PhD, Colin Correnti, PhD, Anne Kisielewski, BS, Allison Kaeding, MD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc

Blood (2019) 134 (Supplement_1): 3925.

https://doi.org/10.1182/blood-2019-130941

Published: 2019

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Hyperstable SGK1 steps out of AKT’s shadow

Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression

Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death

Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas

OBF1 and Oct factors control the germinal center transcriptional program

CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1

Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL

BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells

Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis by using the new oral demethylating agent OR-2100

YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

Tearing ATL apart to find HTLV’s sinister plans

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Protein Phosphatase 2A Activation Dependent Down Regulation of PGC1-Alpha and FOXO1 Phosphorylation with OSU-2S in Human Lymphoma Cells

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

The Clinical and Functional Relevance of the Transforming AKT E17K Mutation in T-ALL

Targeted Protein Degradation of BTK As a Unique Therapeutic Approach for B Cell Malignancies

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

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American Society of Hematology

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