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Journal Articles

Predicting Drug Response and Novel Therapeutic Candidates Using Signatures of Molecular Alterations in Hematologic Malignancies

Guillaume Labilloy, MS, Eric O'Brien, BSc, Brett VanCauwenbergh, BSc, Luke Byerly, BSc, Mitali Basu, MSc, William Seibel, PhD, Erin H. Breese, MD PhD, John Peter Perentesis, MD, Mayur Sarangdhar, PhD

Blood (2018) 132 (Supplement 1): 2219.

https://doi.org/10.1182/blood-2018-99-119933

Published: 2018

Journal Articles

Small Molecule Activators of Protein Phosphatase 2A (SMAPs) Cause c-Myc Degradation and Tumor Growth Suppression in Preclinical Models of Lymphoid Malignancies

Molly M Gallogly, MDPhD, Eric Yuan, MPhil, Sahar Mazhar, BA, Caroline Farrington, BA, Goutham Narla, MD PhD

Blood (2017) 130 (Supplement 1): 2819.

https://doi.org/10.1182/blood.V130.Suppl_1.2819.2819

Published: 2017

Journal Articles

New Therapeutic Opportunities for Pediatric Patients with t(6;11)-Rearranged Acute Myeloid Leukemia

Claudia Tregnago, PhD, Matteo Zampini, PhD, Valeria Bisio, PhD, Barbara Buldini, MD, Stefano Indraccolo, MD, Giuseppe Basso, Franco Locatelli, MD, Martina Pigazzi, PhD

Blood (2016) 128 (22): 749.

https://doi.org/10.1182/blood.V128.22.749.749

Published: 2016

Journal Articles

Synergistic Targeting of Protein Translation and Inhibition of NOTCH Signaling in T-ALL

Marta Sanchez-Martin, PhD, Alberto Ambesi-Impiombato, MDPhD, Luyao Xu, Yue Qin, Daniel Herranz, PhD, Mukesh Bansal, PhD, Tiziana Girardi, Kim De Keersmaecker, Andrea Califano, PhD, Adolfo A. Ferrando, MD PhD

Blood (2015) 126 (23): 3719.

https://doi.org/10.1182/blood.V126.23.3719.3719

Published: 2015

Journal Articles

Bing-Neel Syndrome: A Rare Complication of Waldenstrom’s Macroglobulinemia

Sergio A. Sanchez-Guerrero, MD, Steven P. Treon, MD PhD, Luis Guevara-Arnal, MD, Akram Darwich, MD, Andrea Cardenas-Ortega, MD, Jorge J. Castillo, MD

Blood (2014) 124 (21): 5480.

https://doi.org/10.1182/blood.V124.21.5480.5480

Published: 2014

Journal Articles

Chlorpromazine, an Inhibitor of Intracellular Trafficking of FLT3-ITD and KIT D816V, Shows Prominent Anti-Leukemic Activities Against AML Cells and AML Stem Cells in Vitro and in Vivo.

Shinya Rai, MD, Hirokazu Tanaka, MD, PhD, Mai Suzuki, PhD, Akira Tanimura, Keiko Matsui, MD, PhD, Toshio Watanabe, PhD, Yuzuru Kanakura, MD PhD, Itaru Matsumura

Blood (2014) 124 (21): 269.

https://doi.org/10.1182/blood.V124.21.269.269

Published: 2014

Journal Articles

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Karen A. Urtishak, PhD, Wang Li-San, PhD, David T. Teachey, MD, Tasian K. Sarah, MD, Jeffrey S. Barrett, PhD, I-Ming L. Chen, Susan R. Atlas, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD

Blood (2013) 122 (21): 1669.

https://doi.org/10.1182/blood.V122.21.1669.1669

Published: 2013

Journal Articles

Phenothiazines Induce Apoptosis in T-Cell Acute Lymphoblastic Leukemia by Activating the Phosphatase Activity of the PP2A Tumor Suppressor

Blood (2012) 120 (21): 3558.

https://doi.org/10.1182/blood.V120.21.3558.3558

Published: 2012

Journal Articles

A Screen for Drugs Showing Specific Co-Resistance or Hyper-Sensitivity Upon the Acquisition of Ara-C Resistance In AML

Susan K Rathe, David Largaespada, PhD

Blood (2010) 116 (21): 1844.

https://doi.org/10.1182/blood.V116.21.1844.1844

Published: 2010

Journal Articles

Inhibition of Both Jak2 and STAT5 Enhances Toxicity to Myeloproliferative Cells.

Michal Bar-Natan, M.D, Erik A. Nelson, PhD, Sarah R. Walker, Ph.D., Rosemary Barrett, B.S., David A. Frank, MD, PhD

Blood (2009) 114 (22): 1905.

https://doi.org/10.1182/blood.V114.22.1905.1905

Published: 2009

Journal Articles

Use of SSRIs Not Associated with Increased Bleeding Events in Children: An Analysis of the Michigan Medicaid Database from 2000–2003

Kerry K Powell, MD, Wei Wang, MS, MAS, Kelly J Kelleher, MD, MPH, Sarah H O’Brien, MD, MSc

Blood (2008) 112 (11): 2389.

https://doi.org/10.1182/blood.V112.11.2389.2389

Published: 2008

Journal Articles

HyperCKemia in CML Patients on Imatinib Mesylate.

Joanne D. Hewitt, BScN, Deborah A. Rusnak, RN, Nanette Cox-Kennett, MN, Loree M. Larratt, MD, Robert Turner, MD

Blood (2007) 110 (11): 2965.

https://doi.org/10.1182/blood.V110.11.2965.2965

Published: 2007

Journal Articles

Pimozide Inhibits STAT5 Signaling in Chronic Myelogenous Leukemia and Reduces the Viability of Both Imatinib Sensitive and Imatinib Resistant Cells.

Erik A. Nelson, PhD, Sarah R. Walker, Ph.D., Alicia Kepich, B.S., Shariya Terrell, B.S., Laurie Gashin, B.S., David A. Frank, M.D., Ph.D.

Blood (2007) 110 (11): 2953.

https://doi.org/10.1182/blood.V110.11.2953.2953

Published: 2007

Journal Articles

Inpatient Pharmaceutical Cost of Hematological Agents: A Single Center Report.

Charles V. Wendling, MD, Jonathan Glass, MD, Perry G. Rigby, MD

Blood (2006) 108 (11): 5491.

https://doi.org/10.1182/blood.V108.11.5491.5491

Published: 2006

Journal Articles

Congenital Amniotic Band Syndrome and MLL Rearranged Neonatal Leukemia in an Infant with Multiple Pre-Conception and In Utero Exposures.

Anna Sechser Perl, MD, Blaine W. Robinson, PhD, Jaclyn A. Biegel, PhD, Elaine H. Zackai, MD, Christos P. Kolaris, MD, Carolyn A. Felix, MD

Blood (2006) 108 (11): 4286.

https://doi.org/10.1182/blood.V108.11.4286.4286

Published: 2006

Journal Articles

Rimcazole - A Sigma Receptor Antagonist - As a Potential Novel Therapy for Acute Myeloid Leukemia and Myeloma.

Yogesh Upadhye, MRCP, Stephen Watt, Ph.D, Barbara A. Spruce, MRCP, Ph.D, David T. Bowen, FRCP, MD

Blood (2005) 106 (11): 2486.

https://doi.org/10.1182/blood.V106.11.2486.2486

Published: 2005

Journal Articles

Association between Neuroleptics and Venous Thromboembolism: A Case-Control Study.

Karine Lacut, MD, Gregoire Le Gal, MD, Emmanuel Oger, MD, PhD, Dominique Mottier, MD

Blood (2004) 104 (11): 2601.

https://doi.org/10.1182/blood.V104.11.2601.2601

Published: 2004

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Predicting Drug Response and Novel Therapeutic Candidates Using Signatures of Molecular Alterations in Hematologic Malignancies

Small Molecule Activators of Protein Phosphatase 2A (SMAPs) Cause c-Myc Degradation and Tumor Growth Suppression in Preclinical Models of Lymphoid Malignancies

New Therapeutic Opportunities for Pediatric Patients with t(6;11)-Rearranged Acute Myeloid Leukemia

Synergistic Targeting of Protein Translation and Inhibition of NOTCH Signaling in T-ALL

Bing-Neel Syndrome: A Rare Complication of Waldenstrom’s Macroglobulinemia

Chlorpromazine, an Inhibitor of Intracellular Trafficking of FLT3-ITD and KIT D816V, Shows Prominent Anti-Leukemic Activities Against AML Cells and AML Stem Cells in Vitro and in Vivo.

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Phenothiazines Induce Apoptosis in T-Cell Acute Lymphoblastic Leukemia by Activating the Phosphatase Activity of the PP2A Tumor Suppressor

A Screen for Drugs Showing Specific Co-Resistance or Hyper-Sensitivity Upon the Acquisition of Ara-C Resistance In AML

Inhibition of Both Jak2 and STAT5 Enhances Toxicity to Myeloproliferative Cells.

Use of SSRIs Not Associated with Increased Bleeding Events in Children: An Analysis of the Michigan Medicaid Database from 2000–2003

HyperCKemia in CML Patients on Imatinib Mesylate.

Pimozide Inhibits STAT5 Signaling in Chronic Myelogenous Leukemia and Reduces the Viability of Both Imatinib Sensitive and Imatinib Resistant Cells.

Inpatient Pharmaceutical Cost of Hematological Agents: A Single Center Report.

Congenital Amniotic Band Syndrome and MLL Rearranged Neonatal Leukemia in an Infant with Multiple Pre-Conception and In Utero Exposures.

Rimcazole - A Sigma Receptor Antagonist - As a Potential Novel Therapy for Acute Myeloid Leukemia and Myeloma.

Association between Neuroleptics and Venous Thromboembolism: A Case-Control Study.

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