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Journal Articles

Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas

Blood (2021) 137 (20): 2785–2799.

https://doi.org/10.1182/blood.2020005244

Published: 2021

Includes: Supplemental data

Journal Articles

Preclinical Evaluation of ALS20, a New and Improved Lentiviral Vector for Beta-Globinopathies

Laura Breda, PhD, Valentina Ghiaccio, PhD, Silvia Pires Lourenco, MSc, Danuta Jadwiga Jarocha, PhD, Yasuhiro Ikawa, MD PhD, Naoto Tanaka, PhD, Virginia Guzikowski, Carla Casu, PhD, Kim Smith-Whitley, MD, Janet L. Kwiatkowski, MD MSCE, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 2242.

https://doi.org/10.1182/blood-2019-124043

Published: 2019

Journal Articles

Hax1 Is Indispensable for Neutrophil Development in Zebrafish

Larissa Doll, Narges Aghaallaei, Karl Welte, Julia Skokowa, MD PhD, Baubak Bajoghli

Blood (2019) 134 (Supplement_1): 436.

https://doi.org/10.1182/blood-2019-130226

Published: 2019

Journal Articles

Mutation-Specific Dominant Negative Effects Determine the Phenotype in SRP54 D eficiency

Christoph Schuerch, MSc, Thorsten Schaefer, PhD, Joelle S. Müller, MSc, Pauline Hanns, MSc, Jonas Schärer, BSc, Julia Skokowa, MD PhD, Karl Welte, Raphael Carapito, PhD, Seiamak Bahram, MD, Martina Konantz, PhD, Claudia Lengerke, MD

Blood (2019) 134 (Supplement_1): 437.

https://doi.org/10.1182/blood-2019-127007

Published: 2019

Journal Articles

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

Umapathy N Siddaramappa, PhD, Niren Patel, MBBS, Betty S. Pace, MD, Abdullah Kutlar, MD

Blood (2019) 134 (Supplement_1): 2258.

https://doi.org/10.1182/blood-2019-130924

Published: 2019

Journal Articles

The Mitochondrion: A Link Between Hemolysis and Platelet Activation

Sruti Shiva, PhD

Blood (2019) 134 (Supplement_1): SCI-39.

https://doi.org/10.1182/blood-2019-121112

Published: 2019

Journal Articles

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

Yusuke Higuchi, MD, Jun-ichirou Yasunaga, MD PhD, Yu Mitagami, PhD, Koichi Ohshima, MD PhD, Masao Matsuoka, MD PhD

Blood (2019) 134 (Supplement_1): 1516.

https://doi.org/10.1182/blood-2019-125546

Published: 2019

Journal Articles

Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement

Mark Wunderlich, MS, Jing Chen, Eric O'Brien, BSc, Nicole Manning, Christina Sexton, Luke Byerly, John P Perentesis, Benjamin Mizukawa, James C Mulloy

Blood (2019) 134 (Supplement_1): 3766.

https://doi.org/10.1182/blood-2019-129225

Published: 2019

Journal Articles

Expression of Human SBDS R126T in S bds Null Background Shows Eif6 Dysregulation: An Adult Zebrafish Model for Shwachman-Diamond Syndrome

Usua Oyarbide Cuervas-Mons, PhD MSc, BSc, Matthew Snyderman, MSc, Jacek Topczewski, PhD, Seth J. Corey, MD

Blood (2019) 134 (Supplement_1): 3737.

https://doi.org/10.1182/blood-2019-129014

Published: 2019

Journal Articles

Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity

Hong Mu-Mosley, MD PhD, Lauren B Ostermann, Muharrem Muftuoglu, MD, Wendy Schober, Nalini B Patel, Abishek Vaidya, MS, Challice L. Bonifant, MD PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 3917.

https://doi.org/10.1182/blood-2019-125928

Published: 2019

Journal Articles

Enumerating Functional HSC Clones in the Zebrafish Using Gestalt

Emily M Teets, B.S., Charles Thomas Gregory, BS, Jami L Shaffer, B.S., James S. Blachly, MD, Bradley W Blaser, MD PhD

Blood (2019) 134 (Supplement_1): 3724.

https://doi.org/10.1182/blood-2019-131503

Published: 2019

Journal Articles

Enhancing the Effect of CLL-1 CAR T Cells with Interleukin-15 for Treatment of Acute Myeloid Leukemia

Pinar Ataca Atilla, MD, Haruko Tashiro, MD PhD, Mary Kathryn McKenna, PhD, Madhuwanti Srinivasan, Brian Wesley Simons, Alexandra McLean Stevens, MD PhD, Michele Redell, MD PhD, Maksim Mamonkin, PhD, Malcolm K. Brenner, MD PhD, Erden Atilla, MD

Blood (2019) 134 (Supplement_1): 3912.

https://doi.org/10.1182/blood-2019-127953

Published: 2019

Journal Articles

Targeted Therapy of Acute Chest Syndrome with Recombinant Heme Oxygenase-1 Revealed By the Resistance of Young Transgenic Sickle Cell Mice to Heme-Induced Acute Lung Injury

Rimi Hazra, Samit Ghosh, Bethany Flage, Matthew Crouthamel, Clark Pan, Xiuxia Sun, Bohong Zhang, Joseph Sypek, Solomon Fiifi Ofori-Acquah

Blood (2019) 134 (Supplement_1): 74.

https://doi.org/10.1182/blood-2019-127198

Published: 2019

Journal Articles

CD47 Regulates Red Blood Cell Alloimmunization in Mice

Ryan Jajosky, MD, Connie Arthur, PhD, Jerry Allen, BS, Megan Fuller, BS, Patricia E Zerra, MD, Cheryl Maier, MD PhD, Sean R. Stowell, MD PhD

Blood (2019) 134 (Supplement_1): 100.

https://doi.org/10.1182/blood-2019-131598

Published: 2019

Journal Articles

Targeting Hypersumoylation in Mantle Cell Lymphoma

Walter Hanel, MD PhD, Liudmyla Tsyba, PhD, Dennis Huszar, PhD, Alex Prouty, Xiaoli Zhang, PhD, JoBeth Helmig-Mason, Msc, Bethany L Mundy-Bosse, PhD, Youssef Youssef, MD, Samir Parekh, MD, Kami J. Maddocks, MD, Robert A Baiocchi, MD PhD, Lapo Alinari, MD PhD

Blood (2019) 134 (Supplement_1): 4060.

https://doi.org/10.1182/blood-2019-127363

Published: 2019

Journal Articles

Differential Efficacy of Anti-Sickling and Anti-Inflammatory Mechanisms in a Fluorescent Intravital Microscopy Dorsal Skinfold Vaso-Occlusion Model in Sickle Cell Disease Townes Mice

Sarah Sturtevant, BSc, Alejandra Macias-Garcia, PhD, Sriram Krishnamoorthy, PhD, Arjan van der Flier, PhD, Alexandra Hicks, PhD, Melanie Demers, PhD

Blood (2019) 134 (Supplement_1): 2264.

https://doi.org/10.1182/blood-2019-128922

Published: 2019

Journal Articles

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Stevan P. Tofovic, Edwin K. Jackson, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 2266.

https://doi.org/10.1182/blood-2019-130882

Published: 2019

Journal Articles

Examining the Role of CD30 in an Anaplastic Large Cell Lymphoma Mouse Model

Teresa Poggio, Linda Graessel, Stefanie Kreutmair, Cornelius Miething, Dietmar Pfeifer, Geoffroy Andrieux, Melanie Boerries, Marie Follo, Suzanne Turner, Robert Zeiser, MD, Justus Duyster, MD, Anna Lena Illert

Blood (2019) 134 (Supplement_1): 2542.

https://doi.org/10.1182/blood-2019-125589

Published: 2019

Journal Articles

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Shaowei Qiu, MD, Chengcheng Yan, MD, Andrew J Paterson, PhD, Hui Li, BS, Nick Anderson, BS, Ajay Abraham, PhD, Jianbo He, MD, Mansi Shah, PhD, Puneet Agarwal, Jing Yang, PhD, Min Xie, MD, Rui Lu, PhD, Rob S. Welner, PhD, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 2548.

https://doi.org/10.1182/blood-2019-124948

Published: 2019

Journal Articles

LIM Domain Protein 1 (Ldb1) Is Required for Lmo2 Oncogene-Induced Thymocyte Self-Renewal and T-Cell Leukemia in a Mouse Model of Human T-ALL

Liqi Li, PhD, Apratim Mitra, Bin Zhao, Seeyoung Choi, Jan Lee, Daniel Stamos, Claude Warzecha, Karl Pfeifer, Joyce Hardwick, Bryan Venters, Paul Love, Utpal Dave, MD

Blood (2019) 134 (Supplement_1): 2538.

https://doi.org/10.1182/blood-2019-127534

Published: 2019

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Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas

Preclinical Evaluation of ALS20, a New and Improved Lentiviral Vector for Beta-Globinopathies

Hax1 Is Indispensable for Neutrophil Development in Zebrafish

Mutation-Specific Dominant Negative Effects Determine the Phenotype in SRP54 D eficiency

Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function

The Mitochondrion: A Link Between Hemolysis and Platelet Activation

HTLV-1 Dysregulates IL-6 and IL-10-JAK/STAT Signaling and Induces Leukemia/Lymphoma of Mature CD4+ T Cells with Regulatory T-Cell-like Signatures

Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement

Expression of Human SBDS R126T in S bds Null Background Shows Eif6 Dysregulation: An Adult Zebrafish Model for Shwachman-Diamond Syndrome

Transgenic Expression of IL15 in CD123-Specific BiTE-Secreting Engager T-Cells Results in Improved Anti-AML Activity

Enumerating Functional HSC Clones in the Zebrafish Using Gestalt

Enhancing the Effect of CLL-1 CAR T Cells with Interleukin-15 for Treatment of Acute Myeloid Leukemia

Targeted Therapy of Acute Chest Syndrome with Recombinant Heme Oxygenase-1 Revealed By the Resistance of Young Transgenic Sickle Cell Mice to Heme-Induced Acute Lung Injury

CD47 Regulates Red Blood Cell Alloimmunization in Mice

Targeting Hypersumoylation in Mantle Cell Lymphoma

Differential Efficacy of Anti-Sickling and Anti-Inflammatory Mechanisms in a Fluorescent Intravital Microscopy Dorsal Skinfold Vaso-Occlusion Model in Sickle Cell Disease Townes Mice

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Examining the Role of CD30 in an Anaplastic Large Cell Lymphoma Mouse Model

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

LIM Domain Protein 1 (Ldb1) Is Required for Lmo2 Oncogene-Induced Thymocyte Self-Renewal and T-Cell Leukemia in a Mouse Model of Human T-ALL

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