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Journal Articles

Efficacy of Caplacizumab in Patients with aTTP in the HERCULES Study According to Initial Immunosuppression Regimen

Katerina Pavenski, MD, Paul Knoebl, MD, Marie Scully, Johanna A. Kremer Hovinga, MD Prof, Paul Coppo, MD PhD, Flora Peyvandi, MD PhD, Spero Cataland, MD, Ara Metjian, MD, Javier De La Rubia, Hilde De Winter, MD, Rui de Passos Sousa, Filip Callewaert

Blood (2019) 134 (Supplement_1): 2365.

https://doi.org/10.1182/blood-2019-123126

Published: 2019

Journal Articles

Disruption of ADAMTS13-Autoantibody Complexes with an ADAMTS13 Spacer Domain As a Potential Therapeutic Strategy for Immune Thrombotic Thrombocytopenic Purpura

Konstantine Halkidis, MD PhD, X. Long Zheng, MD, PhD

Blood (2019) 134 (Supplement_1): 88.

https://doi.org/10.1182/blood-2019-125965

Published: 2019

Journal Articles

Evaluation of Markers of Intravascular Hemolysis and Endothelial Dysfunction in Sickle Cell Anemia Patients with and without Hydroxyurea Therapy

Francine Chenou, Bidossessi Wilfried Hounkpe, Igor de Farias Domingos, MSc, Thais Helena Chaves Batista, Rodrigo Marcionilo Santana, Aderson da Silva Araujo, MD PhD, Marcos Andre Cavalcanti Bezerra, PhD, Fernando Ferreira Costa, MD PhD, Maria de Fátima Sonati, MSc, PhD, Erich V De Paula, MD PhD, Magnun Nueldo Nunes Santos, MSc, PhD

Blood (2019) 134 (Supplement_1): 4826.

https://doi.org/10.1182/blood-2019-131169

Published: 2019

Journal Articles

Thrombotic Thrombocytopenic Purpura and Atypical Hemolytic Uremic Syndrome in Pregnancy: A Single Center Retrospective Review

Pallavi Kopparthy, MD, Anita Rajasekhar, MD

Blood (2019) 134 (Supplement_1): 4899.

https://doi.org/10.1182/blood-2019-131846

Published: 2019

Journal Articles

Variable Clinical Presentation of Congenital Thrombotic Thrombocytopenic Purpura in a Large Cohort of Patients Carrying a New Mutation in the CUB1 Domain of ADAMTS13 Gene

Oleg Pikovsky, Maram Arafat, MSc, Hilla Ovadia, PhD, Yoav Sharoni, PhD, Kayed Al-Athamen, MD, Bibi Kanengisser-Pines, MD, Anat Keren-Politansky, PhD, Itai Levi, MD, Ruti Parvari, PhD, Anat Rabinovich, MD

Blood (2018) 132 (Supplement 1): 1139.

https://doi.org/10.1182/blood-2018-99-111253

Published: 2018

Journal Articles

Lysine-Histone Triggers Thrombotic Thrombocytopenic Purpura in Zebrafish and Mice

Liang Zheng, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 294.

https://doi.org/10.1182/blood.V130.Suppl_1.294.294

Published: 2017

Journal Articles

Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after CD19 CAR-T Cell Immunotherapy

Cameron J. Turtle, MBBS, PhD, Kevin A. Hay, MD FRCPC, MSc, Laila-Aicha Hanafi, PhD, Juliane Gust, MDPhD, W. Conrad Liles, MDPhD, José A. López, MD, Junmei Chen, PhD, Dominic W. Chung, PhD, Mark M Wurfel, MDPhD, Susanna Harju-Baker, PhD, Hasan Ozpolat, MD, Daniel Li, PhD, David Myerson, MDPhD, Luis F. Gonzalez-Cuyar, MD, Cecilia Yeung, MD, Kathleen R. Fink, MD, Stanley R. Riddell, MD, David G. Maloney, MD PhD

Blood (2017) 130 (Supplement 1): 805.

https://doi.org/10.1182/blood.V130.Suppl_1.805.805

Published: 2017

Journal Articles

Projected Cost Savings of a Plasmic Score-Based Approach to Patients with Suspected Thrombotic Thrombocytopenic Purpura

Vivek A Upadhyay, MD, Benjamin Geisler, MD, Lova Sun, MD, Christopher P. Stowell, MD PhD, Lynne Uhl, MD, Richard Kaufman, MD, Robert Makar, MD PhD, Pavan Bendapudi, MD

Blood (2017) 130 (Supplement 1): 3742.

https://doi.org/10.1182/blood.V130.Suppl_1.3742.3742

Published: 2017

Journal Articles

Characterizing the United Kingdom Congenital Thrombotic Thrombocytopenic Purpura Population

Ferras Alwan, MBBS, Chiara Vendramin, Ri Liesner, Tina Dutt, Amanda Clark, Jayashree Motwani, Will Lester, Vickie McDonald, Rachel Rayment, Nichola Cooper, MA, MD MRCP, FRCPath, Richard Gooding, Hamish Lyall, Tina Biss, MD, Joost van Veen, Henry G Watson, John-Paul Westwood, Mari Thomas, Marie Scully

Blood (2017) 130 (Supplement 1): 3616.

https://doi.org/10.1182/blood.V130.Suppl_1.3616.3616

Published: 2017

Journal Articles

Utilization and Cost Effectiveness of a Risk Stratified Diagnostic Approach to Patients with Suspected Thrombotic Thrombocytopenic Purpura

Vivek Upadhyay, MD, Benjamin Geisler, Lova Sun, MD, Robert S Makar, MD PhD, Pavan Bendapudi, MD

Blood (2016) 128 (22): 1456.

https://doi.org/10.1182/blood.V128.22.1456.1456

Published: 2016

Journal Articles

Natural History of Patients Affected with Thrombotic Thrombocytopenic Purpura: Milan TTP Registry

Ilaria Mancini, PhD, Silvia Pontiggia, BSc, Barbara Ferrari, MD, Andrea Artoni, MD PhD, Antonino Cannavò, MD, Silvia Maria Trisolini, MD, Luca Facchini, MD, Erminia Rinaldi, MD, Flora Peyvandi, MD PhD

Blood (2016) 128 (22): 3731.

https://doi.org/10.1182/blood.V128.22.3731.3731

Published: 2016

Journal Articles

Presenting ADAMTS13 Antigen Level Correlates with Clinical Outcome in Acute Thrombotic Thrombocytopenic Purpura

Ferras Alwan, Chiara Vendramin, Katy Langley, Debra Ellis, Mari Thomas, John Paul Westwood, Marie Scully, MBBS, MRCP, FRCPath

Blood (2016) 128 (22): 1365.

https://doi.org/10.1182/blood.V128.22.1365.1365

Published: 2016

Journal Articles

Blood ’s 70th anniversary: the elusive von Willebrand factor–cleaving protease

Kenneth Kaushansky

Blood (2016) 127 (18): 2163–2164.

https://doi.org/10.1182/blood-2015-09-636779

Published: 2016

Journal Articles

Non-Proteolytic Regulation of the Multimerization of Von Willebrand Factor By ADAMTS13 Based on a Novel Cysteine Thiol Redundancy

Hanspeter Rottensteiner, PhD, Susanna Skalicky, Birgit Seyfried, PhD, Stefan Kaufmann, Christian Fiedler, Meinhard Hasslacher, PhD, Jing-fei Dong, MD PhD, X. Long Zheng, MD PhD, Barbara Plaimauer, PhD, Friedrich Scheiflinger, PhD

Blood (2015) 126 (23): 2236.

https://doi.org/10.1182/blood.V126.23.2236.2236

Published: 2015

Journal Articles

The Role of ADAMTS13-Specific Circulating Immune Complexes in Prediction of Recurrence of Acquired Thrombotic Thrombocytopenic Purpura

Barbara Ferrari, Carla Valsecchi, Silvia Pontiggia, Ilaria Mancini, Luca Andrea Lotta, Danijela Mikovic, Giovanna Meloni, Flora Peyvandi

Blood (2014) 124 (21): 1467.

https://doi.org/10.1182/blood.V124.21.1467.1467

Published: 2014

Journal Articles

Successful Eculizumab Therapy in Thrombotic Thrombocytopenic Purpura (TTP) Refractory to Plasma Exchange, Steroids and Rituximab

Harjot Kaur, MD, Appalanaidu Sasapu, MD MS, Michele H Fox, MD, Pooja Motwani, MD

Blood (2014) 124 (21): 2794.

https://doi.org/10.1182/blood.V124.21.2794.2794

Published: 2014

Journal Articles

Pregnancies Complicated By Severe Preeclampsia Exhibit Perturbed Von Willebrand Factor (VWF)-Associated Parameters

Danielle N. Drury-Stewart, PhD, Kara K. Hoppe, DO, Kerry W. Lannert, Dominic W. Chung, PhD, Hilary S. Gammill, MD, Jill M. Johnsen, MD

Blood (2013) 122 (21): 3525.

https://doi.org/10.1182/blood.V122.21.3525.3525

Published: 2013

Journal Articles

ADAMTS13 Expressed In Platelets Offers Systemic Protection Against Arterial Thrombosis and Therapeutic Benefits In Murine Models Of Thrombotic Thrombocytopenic Purpura

Brandy Pickens, Ph.D., Yingying Mao, Ph.D., X. Long Zheng, M.D., Ph.D.

Blood (2013) 122 (21): 446.

https://doi.org/10.1182/blood.V122.21.446.446

Published: 2013

Journal Articles

Single-Nucleotide Variations Defining Previously Unreported ADAMTS13 Haplotypes Are Associated With Differential Expression and Activity Of The VWF-Cleaving Protease In a Salvadoran Congenital Thrombotic Thrombocytopenic Purpura Family

Benjamin Kim, M.D., M.Phil., Zachary A. Hing, Andrew Wu, Tal Schiller, Evi B. Struble, Ph.D., David Liuwantara, Ph.D., Pamela H. Kempert, M.D., Eric J. Broxham, M.D., Nathan C. Edwards, Victor J. Marder, M.D., Vijaya L. Simhadri, Ph.D., Zuben E. Sauna, Ph.D., Tom E. Howard, M.D., Ph.D., Chava Kimchi-Sarfaty, Ph.D.

Blood (2013) 122 (21): 2319.

https://doi.org/10.1182/blood.V122.21.2319.2319

Published: 2013

Journal Articles

Secretion and Activity of ADAMTS13 Are Impaired by Cyclosporin A

Vijaya L. Simhadri, Ph.D., Klilah Hershko, MD, Adam Blaisdell, Andrew Wu, Sandy Tseng, Jordan Newell, Ryan Hunt, JaeWon Choi, Zuben E. Sauna, Ph.D., Richard J. Bram, MD, PhD, Anton A. Komar, Ph.D., Chava Kimchi-Sarfaty, Ph.D.

Blood (2012) 120 (21): 3349.

https://doi.org/10.1182/blood.V120.21.3349.3349

Published: 2012

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Efficacy of Caplacizumab in Patients with aTTP in the HERCULES Study According to Initial Immunosuppression Regimen

Disruption of ADAMTS13-Autoantibody Complexes with an ADAMTS13 Spacer Domain As a Potential Therapeutic Strategy for Immune Thrombotic Thrombocytopenic Purpura

Evaluation of Markers of Intravascular Hemolysis and Endothelial Dysfunction in Sickle Cell Anemia Patients with and without Hydroxyurea Therapy

Thrombotic Thrombocytopenic Purpura and Atypical Hemolytic Uremic Syndrome in Pregnancy: A Single Center Retrospective Review

Variable Clinical Presentation of Congenital Thrombotic Thrombocytopenic Purpura in a Large Cohort of Patients Carrying a New Mutation in the CUB1 Domain of ADAMTS13 Gene

Lysine-Histone Triggers Thrombotic Thrombocytopenic Purpura in Zebrafish and Mice

Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after CD19 CAR-T Cell Immunotherapy

Projected Cost Savings of a Plasmic Score-Based Approach to Patients with Suspected Thrombotic Thrombocytopenic Purpura

Characterizing the United Kingdom Congenital Thrombotic Thrombocytopenic Purpura Population

Utilization and Cost Effectiveness of a Risk Stratified Diagnostic Approach to Patients with Suspected Thrombotic Thrombocytopenic Purpura

Natural History of Patients Affected with Thrombotic Thrombocytopenic Purpura: Milan TTP Registry

Presenting ADAMTS13 Antigen Level Correlates with Clinical Outcome in Acute Thrombotic Thrombocytopenic Purpura

Blood ’s 70th anniversary: the elusive von Willebrand factor–cleaving protease

Non-Proteolytic Regulation of the Multimerization of Von Willebrand Factor By ADAMTS13 Based on a Novel Cysteine Thiol Redundancy

The Role of ADAMTS13-Specific Circulating Immune Complexes in Prediction of Recurrence of Acquired Thrombotic Thrombocytopenic Purpura

Successful Eculizumab Therapy in Thrombotic Thrombocytopenic Purpura (TTP) Refractory to Plasma Exchange, Steroids and Rituximab

Pregnancies Complicated By Severe Preeclampsia Exhibit Perturbed Von Willebrand Factor (VWF)-Associated Parameters

ADAMTS13 Expressed In Platelets Offers Systemic Protection Against Arterial Thrombosis and Therapeutic Benefits In Murine Models Of Thrombotic Thrombocytopenic Purpura

Single-Nucleotide Variations Defining Previously Unreported ADAMTS13 Haplotypes Are Associated With Differential Expression and Activity Of The VWF-Cleaving Protease In a Salvadoran Congenital Thrombotic Thrombocytopenic Purpura Family

Secretion and Activity of ADAMTS13 Are Impaired by Cyclosporin A

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