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Journal Articles

The Alpha Emitter Astatine-211 Targeted to CD38 Can Eradicate Multiple Myeloma in Minimal Residual Disease Models

Shyril O'Steen, PhD, Melissa C. Comstock, BS, Johnnie J. Orozco, MD PhD, Donald K. Hamlin, BS, D. Scott Wilbur, PhD, Jon Jones, BS, Aimee Kenoyer, BS, Margaret E. Nartea, BS, Yukang Lin, PhD, Brian W. Miller, PhD, Sherilyn A. Tuazon, MD, Brian G. Till, MD, Ajay K. Gopal, MD, Brenda M. Sandmaier, MD, Oliver W. Press, MD PhD, Damian J. Green, MD

Blood (2018) 132 (Supplement 1): 1941.

https://doi.org/10.1182/blood-2018-99-119555

Published: 2018

Journal Articles

Novel Bispecific Antibody Targeting CD45 and 90 Y-DOTA Is Effective Therapy for Acute Myeloid Leukemia in Preclinical Murine Models

Johnnie J. Orozco, MD PhD, Aimee Kenoyer, BS, Yukang Lin, PhD, Darrell R. Fisher, PhD, Donald K. Hamlin, BS, D. Scott Wilbur, PhD, Alexandra Hernandez, BS, Rosario Guel, Margaret E. Nartea, Shyril O'Steen, PhD, Mark D Hylarides, PhD, Brian G Till, MD, Damian J. Green, MD, Ajay K. Gopal, MD, Kelly D Orcutt, PhD, Karl Dane Wittrup, PhD, Brenda M. Sandmaier, MD, John M. Pagel, MD PhD, Oliver W. Press, MD PhD

Blood (2017) 130 (Supplement 1): 1355.

https://doi.org/10.1182/blood.V130.Suppl_1.1355.1355

Published: 2017

Journal Articles

Pre-Targeted Radioimmunotherapy Employing a Recombinant Bispecific Antibody Using a Murine Xenograft Model of Human Leukemia

Aimee L. Kenoyer, BS, Yukang Lin, PhD, Johnnie J. Orozco, MD PhD, Ethan Balkin, Don Hamlin, BS, Alexandra H. Hernandez, BS, Chen Fang, PhD, Kelly Laird, Sofia H.L. Frost, PhD, Mark Hylarides, PhD, Kelly D. Orcutt, PhD, D Scott Wilbur, PhD, K. Dane Wittrup, PhD, Oliver W. Press, MD PhD, John Pagel, MD PhD

Blood (2014) 124 (21): 3749.

https://doi.org/10.1182/blood.V124.21.3749.3749

Published: 2014

Journal Articles

Anti-CD38 Pretargeted Radioimmunotherapy Eradicates Multiple Myeloma Xenografts In a Murine Model

Damian J. Green, MD, Jon C. Jones, Mark D. Hylarides, PhD, Donald K. Hamlin, BS, D Scott Wilbur, PhD, Yukang Lin, PhD, Aimee L. Kenoyer, BS, Shani L. Frayo, BS, William I. Bensinger, MD, Ajay K. Gopal, MD, Johnnie J. Orozco, MD, PhD, Theodore A. Gooley, PhD, Brent L. Wood, MD, PhD, John M. Pagel, MD, PhD, Oliver W. Press, MD, PhD

Blood (2013) 122 (21): 882.

https://doi.org/10.1182/blood.V122.21.882.882

Published: 2013

Journal Articles

Astatine-211 Conjugated To Anti-CD20 Monoclonal Antibody Eliminates B-Cell Lymphoma In a Mouse Model

Damian J. Green, MD, Mazyar Shadman, MD, MPH, Shani L. Frayo, BS, Jon C. Jones, Mark D. Hylarides, PhD, Aimee L. Kenoyer, BS, D. Scott Wilbur, PhD, Donald K. Hamlin, BS, Yukang Lin, PhD, Ajay K. Gopal, MD, Sofia H.L. Frost, PhD, Johnnie J. Orozco, MD, PhD, John M. Pagel, MD, PhD, Oliver W. Press, MD, PhD

Blood (2013) 122 (21): 4415.

https://doi.org/10.1182/blood.V122.21.4415.4415

Published: 2013

Journal Articles

Anti-CD38 Pretargeted Radioimmunotherapy Demonstrates Therapeutic Efficacy In a Human Multiple Myeloma Mouse Xenograft Model

Damian J. Green, MD, Nural N. Orgun, Mark D. Hylarides, PhD, John M. Pagel, MD, PhD, Donald K. Hamlin, D. Scott Wilbur, PhD, Yukang Lin, PhD, Amiee L. Kenoyer, Shani L. Frayo, BS, William I. Bensinger, MD, Ajay K. Gopal, MD, Johnnie J. Orozco, MD, PhD, Theodore A. Gooley, PhD, Brent L. Wood, MD, PhD, Oliver W. Press, MD, PhD

Blood (2011) 118 (21): 1842.

https://doi.org/10.1182/blood.V118.21.1842.1842

Published: 2011

Journal Articles

Conventional and Pretargeted Radioimmunotherapy with Bismuth-213 to Target and Treat CD20-Expressing Non-Hodgkin Lymphoma: A Preclinical Model for Consolidation Therapy to Eradicate Minimal Residual Disease.

Steven I. Park, MD, Jaideep Shenoi, MD, John M. Pagel, MD, PhD, Donald K. Hamlin, Nural Orgun, Aimee L. Kenoyer, Shani M. Wilbur, BS, Amanda Axtman, D. Scott Wilbur, PhD, Yukang Lin, PhD, Darrell R. Fisher, PhD, Ajay K. Gopal, MD, Damian J. Green, MD, Oliver W. Press, MD, PhD

Blood (2009) 114 (22): 2705.

https://doi.org/10.1182/blood.V114.22.2705.2705

Published: 2009

Journal Articles

Anti-CD45 Ab Pretargeted Radioimmunotherapy Using An Alpha Emitting Radionuclide (213Bi) Delivers Selective Radiation to Human Myeloid Leukemias in a Mouse Xenograft Model and Results in High Rates of Complete Remission and Long Term Survival.

Aimee L. Kenoyer, BS, Oliver W. Press, MD, PhD, Steven I. Park, MD, Tom Back, Donald K. Hamlin, BS, D. Scott Wilbur, PhD, Darrell R. Fisher, PhD, Shani M. Wilbur, BS, Amanda Axtman, BS, Nural Orgun, Yukang Lin, PhD, Ajay K. Gopal, MD, Jaideep Shenoi, MD, Damian J. Green, MD, Frederick R Appelbaum, John M. Pagel, MD, PhD

Blood (2009) 114 (22): 1035.

https://doi.org/10.1182/blood.V114.22.1035.1035

Published: 2009

Journal Articles

Anti-CD45 Pretargeted Radioimmunotherapy in a Nonhuman Primate Model.

Damian J. Green, MD, John M. Pagel, MD, PhD, Eneida R. Nemecek, MD, Anastasia Pantelias, MA, Yukang Lin, PhD, Aimee L. Kenoyer, Darrell R. Fisher, PhD, D.S. Wilbur, PhD, Donald K. Hamlin, Ajay K. Gopal, MD, Oliver W. Press, MD, PhD

Blood (2007) 110 (11): 2336.

https://doi.org/10.1182/blood.V110.11.2336.2336

Published: 2007

Journal Articles

Conventional and Pretargeted Radioimmunotherapy Using an Anti-Murine CD45 Monoclonal Antibody in a Syngeneic, Disseminated Murine Leukemia Model.

John M. Pagel, MD,PhD, Nathan Hedin, Lacey Drouet, Anastasia Pantelias, Yukang Lin, PhD, Don Hamlin, Darrell Fisher, PhD, D. Scott Wilbur, MD, Ajay K. Gopal, MD, Damian Green, MD, Frederick R. Appelbaum, MD, Oliver W. Press, MD,PhD

Blood (2006) 108 (11): 570.

https://doi.org/10.1182/blood.V108.11.570.570

Published: 2006

Journal Articles

Extracorporeal Adsorption Following Infusion of Radiolabeled Anti-CD20 Antibody Clears Unbound Radioimmunoconjugate from the Circulation and Reduces Radiation Exposure of Normal Organs in the Nonhuman Primate.

Damian J. Green, MD, Eneida R. Nemecek, MD, Nathan Hedin, BS, Anastasia Pantelias, MA, Yukang Lin, PhD, John M. Pagel, MD,PhD, Darrell R. Fisher, PhD, Don K. Hamlin, BS, D. Scott Wilbur, PhD, Ajay Gopal, MD, Rune Nilsson, PhD, Bengt E.B. Sandberg, PhD, Oliver W. Press, MD,PhD

Blood (2006) 108 (11): 2500.

https://doi.org/10.1182/blood.V108.11.2500.2500

Published: 2006

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The Alpha Emitter Astatine-211 Targeted to CD38 Can Eradicate Multiple Myeloma in Minimal Residual Disease Models

Novel Bispecific Antibody Targeting CD45 and 90 Y-DOTA Is Effective Therapy for Acute Myeloid Leukemia in Preclinical Murine Models

Pre-Targeted Radioimmunotherapy Employing a Recombinant Bispecific Antibody Using a Murine Xenograft Model of Human Leukemia

Anti-CD38 Pretargeted Radioimmunotherapy Eradicates Multiple Myeloma Xenografts In a Murine Model

Astatine-211 Conjugated To Anti-CD20 Monoclonal Antibody Eliminates B-Cell Lymphoma In a Mouse Model

Anti-CD38 Pretargeted Radioimmunotherapy Demonstrates Therapeutic Efficacy In a Human Multiple Myeloma Mouse Xenograft Model

Conventional and Pretargeted Radioimmunotherapy with Bismuth-213 to Target and Treat CD20-Expressing Non-Hodgkin Lymphoma: A Preclinical Model for Consolidation Therapy to Eradicate Minimal Residual Disease.

Anti-CD45 Ab Pretargeted Radioimmunotherapy Using An Alpha Emitting Radionuclide (213Bi) Delivers Selective Radiation to Human Myeloid Leukemias in a Mouse Xenograft Model and Results in High Rates of Complete Remission and Long Term Survival.

Anti-CD45 Pretargeted Radioimmunotherapy in a Nonhuman Primate Model.

Conventional and Pretargeted Radioimmunotherapy Using an Anti-Murine CD45 Monoclonal Antibody in a Syngeneic, Disseminated Murine Leukemia Model.

Extracorporeal Adsorption Following Infusion of Radiolabeled Anti-CD20 Antibody Clears Unbound Radioimmunoconjugate from the Circulation and Reduces Radiation Exposure of Normal Organs in the Nonhuman Primate.

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