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Journal Articles

Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

Blood (2019) 134 (Supplement_1): 1922.

https://doi.org/10.1182/blood-2019-127743

Published: 2019

Journal Articles

ASXL1-Mutated Donor HSCs Evolved into FLT3-ITD Positive AML in the Unrelated Donor and FLT3-ITD Negative AML in the Recipient after Transplant

Zhongwen Liu, MD, Hongxing Liu, MD, Yanli Zhang, MD, Dai Kong, MD, Jie Shi, MD, Yin Zhang, MD, Meiying Wen, Yongping Song, MD PhD, Chunrong Tong, MD, Mingyi Chen, MD PhD, William J. Murphy, PhD, Kai Sun, MD PhD

Blood (2015) 126 (23): 5403.

https://doi.org/10.1182/blood.V126.23.5403.5403

Published: 2015

Journal Articles

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Blood (2015) 126 (23): 147.

https://doi.org/10.1182/blood.V126.23.147.147

Published: 2015

Journal Articles

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

Blood (2014) 124 (21): 535.

https://doi.org/10.1182/blood.V124.21.535.535

Published: 2014

Journal Articles

Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice

Annie Mirsoian, Myriam N. Bouchlaka, BS, PhD, Gail Sckisel, PhD, Mingyi Chen, MD PhD, Chien-Chun Steven Pai, Emanuel Maverakis, MD, Richard Spencer, MD PhD FACP, Kenneth Fishbein, PhD, Sana Siddiqui, PhD, Arta Monjazeb, MDPhD, Bronwen Martin, PhD, Stuart Maudsley, PhD, Charles Hesdorffer, Luigi Ferrucci, MD PhD, Dan L. Longo, MD, Bruce R. Blazar, MD, Robert Wiltrout, PhD, Dennis D Taub, PhD, William J Murphy, PhD

Blood (2014) 124 (21): 460.

https://doi.org/10.1182/blood.V124.21.460.460

Published: 2014

Journal Articles

The Impact of Age and Body Fat on Graft-Versus-Host Disease (GVHD) in Mice

Chien-Chun Steven Pai, Mingyi Chen, MD PhD, Lam Khuat, Annie Mirsoian, Anthony E Zamora, Steven Grossenbacher, Christine Mall, Arta Monjazeb, MDPhD, Julian Perks, PhD, Shuaib Juma, Mehrdad Abedi, MD, William J Murphy, PhD

Blood (2014) 124 (21): 1100.

https://doi.org/10.1182/blood.V124.21.1100.1100

Published: 2014

Journal Articles

Therapeutic Effects of MLN4924 on Sclerodermatous Chronic Graft Versus Host Disease

Chien-Chun Steven Pai, Mingyi Chen, MD PhD, Anthony E Zamora, Lam Khuat, Steven Grossenbacher, William J Murphy, PhD, Mehrdad Abedi, MD

Blood (2014) 124 (21): 3816.

https://doi.org/10.1182/blood.V124.21.3816.3816

Published: 2014

Journal Articles

Natural Killer Cell Licensing Delineates NK “Helper/Repair” and NK “Effector/Suppressor” Subsets During Viral Infections

Can M. Sungur, Anthony E. Zamora, Ethan G. Aguilar, Yajarayma Tang-Feldman, Juan Du, Nicole Baumgarth, Mingyi Chen, MD, PhD, Claire Pomeroy, Jeffrey M. Venstrom, MD, William J. Murphy, PhD

Blood (2013) 122 (21): 13.

https://doi.org/10.1182/blood.V122.21.13.13

Published: 2013

Journal Articles

Evidence That Novel NK-NK Cell Subset Regulation Exists With Regard To Effects In Tumor and Viral Models

Ethan G Aguilar, Can M Sungur, Anthony E Zamora, William J Murphy, PhD

Blood (2013) 122 (21): 1038.

https://doi.org/10.1182/blood.V122.21.1038.1038

Published: 2013

Journal Articles

Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model

Blood (2013) 122 (21): 292.

https://doi.org/10.1182/blood.V122.21.292.292

Published: 2013

Journal Articles

Organ-Specific Protection By Bortezomib On The Treatment Of Cutaneous Chronic and Acute GvHD

Chien-Chun Pai, Annie Mirsoian, Steven Grossenbacher, Erik Ames, Kai Sun, MD.PhD, Mingyi Chen, MD, PhD, Bruce R Blazar, MD, Mehrdad Abedi, MD, William J Murphy, PhD

Blood (2013) 122 (21): 4473.

https://doi.org/10.1182/blood.V122.21.4473.4473

Published: 2013

Journal Articles

Donor B-Cell Alloantibody Deposition and Germinal Center Formation Are Required for the Development of Murine Chronic Gvhd and Bronchiolitis Obliterans

Mathangi Srinivasan, PhD, Ryan Flynn, Andrew Price, Ann Ranger, PhD, Jeffrey L Browning, Patricia A Taylor, DVM, Jerome Ritz, MD, Joseph H. Antin, MD, William J Murphy, PhD, Leo Luznik, Mark Shlomchik, MD, PhD, Angela Panoskaltsis-Mortari, PhD, Bruce R. Blazar, MD

Blood (2011) 118 (21): 307.

https://doi.org/10.1182/blood.V118.21.307.307

Published: 2011

Journal Articles

Organ-Specific Protection from CD8 + T Cell-Mediated Acute Skin GVHD by Bortezomib Administration Correlates with Decreased IL-6.

Kai Sun, MD, Gail Sckisel, Julia Tietze, MD, Minghui Li, PhD, Thomas Sayers, PhD, Bruce R. Blazar, MD, William J. Murphy, PhD

Blood (2010) 116 (21): 3735.

https://doi.org/10.1182/blood.V116.21.3735.3735

Published: 2010

Journal Articles

The Antioxidant Inflammation Modulator, CDDO-Me Promotes Myelopoiesis in Mice.

Lisbeth A. Welniak, PhD, Salif Harouna, David Prosser, Erik Ames, Colin Meyer, M.D., William J. Murphy, PhD

Blood (2008) 112 (11): 2335.

https://doi.org/10.1182/blood.V112.11.2335.2335

Published: 2008

Journal Articles

Donor T Cells Lacking IFN-Gamma Receptor Expression Enhance Donor Myeloid Engraftment and Decrease Early Acute Graft-Versus-Host Disease Mortality Following Allogeneic Bone Marrow Transplantation

Kai Sun, MD, Minghui Li, Mark A. Hubbard, Lisbeth A. Welniak, PhD, William J. Murphy, PhD

Blood (2008) 112 (11): 3514.

https://doi.org/10.1182/blood.V112.11.3514.3514

Published: 2008

Journal Articles

Dissociating GVT from GVHD in Murine BMT Models through TNFα Dependent CD4+ T Cell Mediated GVHD and IFNγ Dependent CD8+ T Cell Mediated Anti-Tumor Effects.

William J. Murphy, PhD, Minghui Li, Angela Panoskaltsis-Mortari, PhD, Bruce R. Blazar, MD, Thomas J. Sayers, PhD, Sergei Nedospasov, PhD, Dennis D. Taub, PhD, Lisbeth A. Welniak, PhD, Kai Sun, PhD

Blood (2007) 110 (11): 69.

https://doi.org/10.1182/blood.V110.11.69.69

Published: 2007

Journal Articles

CD4 + CD25 + Foxp3 + Regulatory T Cell Function Outside the Immune System: Differential Regulation of Hematopoietic Progenitor Cell Populations.

Maite Urbieta, Isabel Barao, PhD, Angela Panoskaltsis-Mortari, PhD, Bruce R. Blazar, MD, William J. Murphy, PhD, Robert B. Levy, PhD

Blood (2007) 110 (11): 64.

https://doi.org/10.1182/blood.V110.11.64.64

Published: 2007

Journal Articles

Regulation of Hematopoietic Colony Forming Cells by CD4 + CD25 + T Cells: A Role for T Regulatory Cells in Hematopoiesis?.

Maite Urbieta, BS, Isabel Barao, PhD, Monica Jones, William J. Murphy, PhD, Robert B. Levy, PhD

Blood (2006) 108 (11): 3181.

https://doi.org/10.1182/blood.V108.11.3181.3181

Published: 2006

Journal Articles

Removal of Donor CD4+ T Cells Markedly Promotes Graft-Versus-Tumor (GVT) Effects and Inhibits GVHD-Dependent Toxicity Associated with Prolonged Bortezomib Administration after Allogeneic BMT.

William J. Murphy, PhD, Lisbeth A. Welniak, PhD, Minghui Li, Thomas J. Sayers, PhD, Angela Panoskaltsis-Mortari, PhD, Bruce R. Blazar, MD, Kai Sun, MD, PhD

Blood (2006) 108 (11): 3160.

https://doi.org/10.1182/blood.V108.11.3160.3160

Published: 2006

Journal Articles

Antibodies to CD40 Promote Dendritic Cell Recovery and Anti-Tumor Effects after Syngeneic Bone Marrow Transplant (BMT).

Lisbeth A. Welniak, PhD, Vanessa Berner, PhD, Bruce R. Blazar, MD, Robert H. Wiltrout, PhD, William J. Murphy, PhD

Blood (2005) 106 (11): 1305.

https://doi.org/10.1182/blood.V106.11.1305.1305

Published: 2005

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Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

ASXL1-Mutated Donor HSCs Evolved into FLT3-ITD Positive AML in the Unrelated Donor and FLT3-ITD Negative AML in the Recipient after Transplant

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice

The Impact of Age and Body Fat on Graft-Versus-Host Disease (GVHD) in Mice

Therapeutic Effects of MLN4924 on Sclerodermatous Chronic Graft Versus Host Disease

Natural Killer Cell Licensing Delineates NK “Helper/Repair” and NK “Effector/Suppressor” Subsets During Viral Infections

Evidence That Novel NK-NK Cell Subset Regulation Exists With Regard To Effects In Tumor and Viral Models

Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model

Organ-Specific Protection By Bortezomib On The Treatment Of Cutaneous Chronic and Acute GvHD

Donor B-Cell Alloantibody Deposition and Germinal Center Formation Are Required for the Development of Murine Chronic Gvhd and Bronchiolitis Obliterans

Organ-Specific Protection from CD8 + T Cell-Mediated Acute Skin GVHD by Bortezomib Administration Correlates with Decreased IL-6.

The Antioxidant Inflammation Modulator, CDDO-Me Promotes Myelopoiesis in Mice.

Donor T Cells Lacking IFN-Gamma Receptor Expression Enhance Donor Myeloid Engraftment and Decrease Early Acute Graft-Versus-Host Disease Mortality Following Allogeneic Bone Marrow Transplantation

Dissociating GVT from GVHD in Murine BMT Models through TNFα Dependent CD4+ T Cell Mediated GVHD and IFNγ Dependent CD8+ T Cell Mediated Anti-Tumor Effects.

CD4 + CD25 + Foxp3 + Regulatory T Cell Function Outside the Immune System: Differential Regulation of Hematopoietic Progenitor Cell Populations.

Regulation of Hematopoietic Colony Forming Cells by CD4 + CD25 + T Cells: A Role for T Regulatory Cells in Hematopoiesis?.

Removal of Donor CD4+ T Cells Markedly Promotes Graft-Versus-Tumor (GVT) Effects and Inhibits GVHD-Dependent Toxicity Associated with Prolonged Bortezomib Administration after Allogeneic BMT.

Antibodies to CD40 Promote Dendritic Cell Recovery and Anti-Tumor Effects after Syngeneic Bone Marrow Transplant (BMT).

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