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Journal Articles

Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

Masashi Miyauchi, Yusuke ITO, MD, Fumio Nakahara, MD PhD, Fumi Nakamura, MD PhD, Yuki Iwasaki, Taiki Kawagoshi, Yuki Kagoya, MD PhD, Shunya Arai, MD PhD, Mineo Kurokawa, MD PhD

Blood (2019) 134 (Supplement_1): 720.

https://doi.org/10.1182/blood-2019-126348

Published: 2019

Journal Articles

Calcium/Calmodulin Dependent Protein Kinase 2 Gamma Is Identified As a Potential Therapeutic Target of Myelofibrosis Using Disease-Specific Induced Pluripotent Stem Cells

Masashi Miyauchi, MD PhD, Ken Sasaki, MD, Kazuki Taoka, MD PhD, Yosuke Masamoto, MD PhD, Sho Yamazaki, MD PhD, Shunya Arai, MD PhD, Mineo Kurokawa, MD PhD

Blood (2018) 132 (Supplement 1): 3054.

https://doi.org/10.1182/blood-2018-99-113285

Published: 2018

Journal Articles

Overall Survival in Acquired Pure Red Cell Aplasia in Adults Following Immunosuppressive Therapy: Preliminary Results from the Nationwide Cohort Study (PRCA2016)

Naohito Fujishima, MD, Makoto Hirokawa, MD PhD, Kenichi Sawada, MD, Shinji Nakao, MD PhD, Yuji Yonemura, MD PhD, Akira Matsuda, MD, Norio Komatsu, MD PhD, Hideo Harigae, MD, Akiko Saito, MD, Kaoru Tohyama, MD, Itaru Matsumura, MD, Mineo Kurokawa, MD PhD, Shunya Arai, MD PhD, Kinuko Mitani, MD

Blood (2018) 132 (Supplement 1): 2593.

https://doi.org/10.1182/blood-2018-99-114245

Published: 2018

Journal Articles

Human Germline HLTF E259K Mutation Identified in Familial MDS Patients Accumulates DNA Damage through Impaired PCNA Polyubiquitination

Kensuke Takaoka, Masahito Kawazu, Junji Koya, Akihide Yoshimi, Yosuke Masamoto, MD PhD, Hiroaki Maki, Takashi Toya, Takashi Kobayashi, Yasuhito Nannya, MD PhD, Shunya Arai, MD PhD, Hironori Ueno, Kenshi Suzuki, Hironori Harada, Atsushi Manabe, Yasuhide Hayashi, Hiroyuki Mano, MDPhD, Mineo Kurokawa, MD PhD

Blood (2017) 130 (Supplement 1): 4238.

https://doi.org/10.1182/blood.V130.Suppl_1.4238.4238

Published: 2017

Journal Articles

Modeling ASXL1 Mutation Revealed Myelodysplasia Caused By Derepression of p16Ink4a through Aberrant PRC1-Mediated Histone Modification

Masahiro Uni, MD PhD, Yosuke Masamoto, MD PhD, Tomohiko Sato, MD PhD, Shunya Arai, MD PhD, Eiji Hara, PhD, Mineo Kurokawa, MD PhD

Blood (2017) 130 (Supplement 1): 118.

https://doi.org/10.1182/blood.V130.Suppl_1.118.118

Published: 2017

Journal Articles

Acquired Gene Mutation of MAP4K2 Identified from Myelodysplastic Syndromes Patients Confers Azacitidine Resistance

Ayato Tsukamoto, MD PhD, Yosuke Masamoto, MD PhD, Koichiro Doi, Shunya Arai, MD PhD, Shinichi Morishita, Mineo Kurokawa, MD PhD

Blood (2017) 130 (Supplement 1): 1242.

https://doi.org/10.1182/blood.V130.Suppl_1.1242.1242

Published: 2017

Journal Articles

Successful MPB Therapy Followed By Bortezomib Maintenance for Non-Transplant Eligible Patients with Newly Diagnosed Multiple Myeloma: Japanese Phase 2 Study - Broad-J Study

Blood (2017) 130 (Supplement 1): 5432.

https://doi.org/10.1182/blood.V130.Suppl_1.5432.5432

Published: 2017

Journal Articles

Clinical Outcomes of Patients with Primary Myelofibrosis in Japan: A Nationwide Survey over a 17-Year Study Period

Katsuto Takenaka, MD PhD, Kazuya Shimoda, MD, PhD, Naoyuki Uchida, MDPhD, Taizo Shimomura, MD PhD, Koji Nagafuji, MD PhD, Tadakazu Kondo, MD PhD, Hirohiko Shibayama, MDPhD, Takehiko Mori, MD PhD, Kensuke Usuki, MD PhD, Taichi Azuma, MDPhD, Yutaka Tsutsumi, MD PhD, Junji Tanaka, MD PhD, Hitomi Dairaku, Keitaro Matsuo, MDPhD, Keiya Ozawa, MD PhD, Mineo Kurokawa, MD, PhD, Shunya Arai, MD, PhD, Koichi Akashi, MD PhD

Blood (2016) 128 (22): 3126.

https://doi.org/10.1182/blood.V128.22.3126.3126

Published: 2016

Journal Articles

Patient-Derived Induced Pluripotent Stem Cells Revealed ADAM8/CD156 As a Novel Marker of TKI-Resistant Chronic Myeloid Leukemia Cells

Masashi Miyauchi, MD, PhD, Shunya Arai, MD, PhD, Akira Honda, MD PhD, Sho Yamazaki, MD, PhD, Keisuke Kataoka, MD PhD, Akihide Yoshimi, MD, PhD, Kazuki Taoka, MD, PhD, Keiki Kumano, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2016) 128 (22): 1878.

https://doi.org/10.1182/blood.V128.22.1878.1878

Published: 2016

Journal Articles

Association of Increased Ring Ssideroblasts with Inferior Survival in Patients with Myelodysplastic Syndrome with Multi-Lineage Dysplasia

Hiroshi Kawabata, MD PhD, Kaoru Tohyama, MD PhD, Akira Matsuda, MD PhD, Kayano Araseki, MD PhD, Tomoko Hata, MD PhD, Takahiro Suzuki, MD, PhD, Hidekazu Kayano, MD PhD, Kei Shinbo, MT, Kensuke Usuki, MD PhD, Akira Hangaishi, MD PhD, Shigeru Chiba, MD, PhD, Nogawa Masaharu, MD PhD, Nobuyoshi Arima, MD PhD, Takayuki Ishikawa, MD PhD, Keiya Ozawa, MD PhD, Shunya Arai, MD, PhD, Mineo Kurokawa, MD, PhD, Akifumi Takaori-Kondo, MD PhD

Blood (2016) 128 (22): 5530.

https://doi.org/10.1182/blood.V128.22.5530.5530

Published: 2016

Journal Articles

Single-Cell Gene Expression Analysis Identifies Alcam As a Novel Candidate Therapeutic Target in AML

Arika Shimura-Nukina, MD PhD, Yosuke Masamoto, MD PhD, Yuki Kagoya, MD PhD, Shunya Arai, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2016) 128 (22): 3915.

https://doi.org/10.1182/blood.V128.22.3915.3915

Published: 2016

Journal Articles

Patient-Derived Induced Pluripotent Stem Cells Identified SLITRK4 As a Causative Gene of Chronic Myelomonocytic Leukemia

Sho Yamazaki, MD, PhD, Kazuki Taoka, MD, PhD, Shunya Arai, MD, PhD, Masashi Miyauchi, MD, PhD, Keisuke Kataoka, MD PhD, Akihide Yoshimi, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2016) 128 (22): 1134.

https://doi.org/10.1182/blood.V128.22.1134.1134

Published: 2016

Journal Articles

Identification of Somatic Mutation Contributing to Chemotherapy Resistance in Acute Myeloid Leukemia

Akira Honda, MD, PhD, Junji Koya, MD, PhD, Akihide Yoshimi, MD PhD, Keisuke Kataoka, MD PhD, Shunya Arai, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2016) 128 (22): 600.

https://doi.org/10.1182/blood.V128.22.600.600

Published: 2016

Journal Articles

Serum LDH Is Useful to Predict Prognosis for Intermediate-Risk Myelodysplastic Syndrome

Kiyomi Morita, MD, Shunya Arai, MD, PhD, Yasunori Kogure, MD, Akira Honda, MD, Kumi Nakazaki, MD, PhD, Mineo Kurokawa, MD

Blood (2015) 126 (23): 5255.

https://doi.org/10.1182/blood.V126.23.5255.5255

Published: 2015

Journal Articles

Adipocyte-Derived Adiponectin Positively Regulates Exit from Quiescence of Hematopoietic Stem Cells By Potentiating mTORC1 Activation after Myelotoxic Injury

Yosuke Masamoto, MDPhD, Shunya Arai, MD, PhD, Tomohiko Sato, MD PhD, Iseki Takamoto, MD PhD, Naoto Kubota, MD PhD, Takashi Kadowaki, MD PhD, Mineo Kurokawa, MD PhD

Blood (2015) 126 (23): 777.

https://doi.org/10.1182/blood.V126.23.777.777

Published: 2015

Journal Articles

Disease-Specific Induced Pluripotent Stem Cells Recapitulate The Pathophysiology Of Familial Platelet Disorder With Predisposition To Acute Myelogenous Leukemia

Shunya Arai, MD, PhD, Hiromitsu Iiduka, MD, Naoya Takayama, M.D., Ph.D., Miyauchi Masashi, MD, Kazuki Taoka, MD, PhD, Keisuke Kataoka, MD, PhD, Masataka Hosoi, MD, PhD, Keiki Kumano, MD, PhD, Koji Eto, M.D., Ph.D., Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 1188.

https://doi.org/10.1182/blood.V122.21.1188.1188

Published: 2013

Journal Articles

The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation

Akihide Yoshimi, MD, PhD, Takashi Toya, MD, Masahiro Nakagawa, MD, PhD, Masahito Kawazu, MD, PhD, Yasuhito Nannya, MD, PhD, Motoshi Ichikawa, MD, PhD, Shunya Arai, MD, PhD, Hironori Harada, MD, PhD, Kensuke Usuki, MD, PhD, Yasuhide Hayashi, MD, PhD, Etsuro Ito, MD, PhD, Keita Kirito, MD, PhD, Hideaki Nakajima, MD, PhD, Hiroyuki Mano, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 739.

https://doi.org/10.1182/blood.V122.21.739.739

Published: 2013

Journal Articles

JAK2V617F Mutation Evokes Paracrine DNA Damage To Adjacent Normal Cells Via Secretion Of Lipocalin-2

Yuki Kagoya, MD, PhD, Shunya Arai, MD, PhD, Akihide Yoshimi, MD, PhD, Takako Tsuruta-Kishino, Keisuke Kataoka, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 266.

https://doi.org/10.1182/blood.V122.21.266.266

Published: 2013

Journal Articles

Modeling Chronic Myelomonocytic Leukemia Through Patient-Derived Induced Pluripotent Stem Cells

Keisuke Kataoka, MD, PhD, Kazuki Taoka, MD, PhD, Masashi Miyauchi, M.D., Ph.D., Masataka Hosoi, M.D., Ph.D., Keiki Kumano, MD, PhD, Shunya Arai, MD, PhD, Kazuhiro Toyama, M.D., Ph.D., Genta Nagae, M.D., Ph.D., Wei Qu, Ph.D., Shinichi Morishita, Ph.D., Hiroyuki Aburatani, M.D., Ph.D., Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 864.

https://doi.org/10.1182/blood.V122.21.864.864

Published: 2013

Journal Articles

A Randomized Controlled Study Evaluating The Efficacy Of Aprepitant For Highly Emetogenic Chemotherapies In Hematological Malignancies

Ryo Nasu, Dr, Yasuhito Nannya, MD, PhD, Akihide Yoshimi, MD, PhD, Masataka Hosoi, M.D., Ph.D., Kouki Ueda, MD, PhD, Yumiko Yoshiki, MD, PhD, Shunya Arai, MD, PhD, Akihito Shinohara, M.D., Ph.D., Fumihiko Nakamura, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 1790.

https://doi.org/10.1182/blood.V122.21.1790.1790

Published: 2013

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Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

Calcium/Calmodulin Dependent Protein Kinase 2 Gamma Is Identified As a Potential Therapeutic Target of Myelofibrosis Using Disease-Specific Induced Pluripotent Stem Cells

Overall Survival in Acquired Pure Red Cell Aplasia in Adults Following Immunosuppressive Therapy: Preliminary Results from the Nationwide Cohort Study (PRCA2016)

Human Germline HLTF E259K Mutation Identified in Familial MDS Patients Accumulates DNA Damage through Impaired PCNA Polyubiquitination

Modeling ASXL1 Mutation Revealed Myelodysplasia Caused By Derepression of p16Ink4a through Aberrant PRC1-Mediated Histone Modification

Acquired Gene Mutation of MAP4K2 Identified from Myelodysplastic Syndromes Patients Confers Azacitidine Resistance

Successful MPB Therapy Followed By Bortezomib Maintenance for Non-Transplant Eligible Patients with Newly Diagnosed Multiple Myeloma: Japanese Phase 2 Study - Broad-J Study

Clinical Outcomes of Patients with Primary Myelofibrosis in Japan: A Nationwide Survey over a 17-Year Study Period

Patient-Derived Induced Pluripotent Stem Cells Revealed ADAM8/CD156 As a Novel Marker of TKI-Resistant Chronic Myeloid Leukemia Cells

Association of Increased Ring Ssideroblasts with Inferior Survival in Patients with Myelodysplastic Syndrome with Multi-Lineage Dysplasia

Single-Cell Gene Expression Analysis Identifies Alcam As a Novel Candidate Therapeutic Target in AML

Patient-Derived Induced Pluripotent Stem Cells Identified SLITRK4 As a Causative Gene of Chronic Myelomonocytic Leukemia

Identification of Somatic Mutation Contributing to Chemotherapy Resistance in Acute Myeloid Leukemia

Serum LDH Is Useful to Predict Prognosis for Intermediate-Risk Myelodysplastic Syndrome

Adipocyte-Derived Adiponectin Positively Regulates Exit from Quiescence of Hematopoietic Stem Cells By Potentiating mTORC1 Activation after Myelotoxic Injury

Disease-Specific Induced Pluripotent Stem Cells Recapitulate The Pathophysiology Of Familial Platelet Disorder With Predisposition To Acute Myelogenous Leukemia

The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation

JAK2V617F Mutation Evokes Paracrine DNA Damage To Adjacent Normal Cells Via Secretion Of Lipocalin-2

Modeling Chronic Myelomonocytic Leukemia Through Patient-Derived Induced Pluripotent Stem Cells

A Randomized Controlled Study Evaluating The Efficacy Of Aprepitant For Highly Emetogenic Chemotherapies In Hematological Malignancies

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