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Sean J Morrison
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Journal Articles

Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors

Open Access
Stefano Comazzetto, Daniel L. Cassidy, Andrew W. DeVilbiss, Elise C. Jeffery, Bethany R. Ottesen, Amanda R. Reyes, Animesh Paul, Suraj Bansal, Stephanie Z. Xie, Sarah Muh, Thomas P. Mathews, Brandon Chen, Zhiyu Zhao, Sean J. Morrison
Journal: Blood
Blood (2025) 145 (1): 114–126.
https://doi.org/10.1182/blood.2024024769
Published: 2025
Includes: Supplemental data
Journal Articles

Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis

Available to Purchase
Wenqing Wang, Martin Arreola, Thomas Mathews, Andrew DeVilbiss, Zhiyu Zhao, Misty Martin-Sandoval, Abdulvasey Mohammed, Giorgia Benegiamo, Avni Awani, Ludger Goeminne, Daniel Dever, Yusuke Nakauchi, Matthew H. Porteus, Mara Pavel-Dinu, Waleed Al-Herz, Johan Auwerx, Sean J. Morrison, Katja G. Weinacht
Journal: Blood
Blood (2024) 144 (26): 2718–2734.
https://doi.org/10.1182/blood.2024024123
Published: 2024
Includes: Supplemental data
Journal Articles

Leptin Receptor+ Stromal Cells Create a Perisinusoidal Niche for Thrombopoiesis in the Bone Marrow By Synthesizing Cxcl14

Free
Yuanyuan Xue, Salma Merchant, Amanda Reyes, Maowu Luo, Sean J. Morrison
Journal: Blood
Blood (2024) 144 (Supplement 1): 564.
https://doi.org/10.1182/blood-2024-205682
Published: 2024
Journal Articles

Therapeutic Synergy from Combined Inhibition of the SERCA Channel and MAPK Signaling Pathway in MAPK-Dependent Leukemia

Free
Meng Wang, MD PhD MRCP, Ugur Eskiocak, PhD, Michalis Agathokleous, PhD, Stacy Yuan, Charles Crawley, MD(London) FRCP FCPath, Sean J. Morrison, PhD
Journal: Blood
Blood (2015) 126 (23): 1264.
https://doi.org/10.1182/blood.V126.23.1264.1264
Published: 2015
Journal Articles

Oncogenic Nras Increases Hematopoietic Stem Cell Proliferation and Self-Renewal Through a Bimodal Effect

Free
Qing Li, M.D., Ph.D., Natacha Bohin, B.S., Tiffany Wen, B.S., Kevin M. Shannon, MD, Sean J. Morrison, Ph.D
Journal: Blood
Blood (2012) 120 (21): 119.
https://doi.org/10.1182/blood.V120.21.119.119
Published: 2012
Journal Articles

Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers

Free
Brief Report
Andre Larochelle, Michael Savona, Michael Wiggins, Stephanie Anderson, Brian Ichwan, Keyvan Keyvanfar, Sean J. Morrison, Cynthia E. Dunbar
Journal: Blood
Blood (2011) 117 (5): 1550–1554.
https://doi.org/10.1182/blood-2009-03-212803
Published: 2011
Includes: Supplemental data
Journal Articles

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

Free
Fei Liu, Jae Y. Lee, Huijun Wei, Osamu Tanabe, James D. Engel, Sean J. Morrison, Jun-Lin Guan
Journal: Blood
Blood (2010) 116 (23): 4806–4814.
https://doi.org/10.1182/blood-2010-06-288589
Published: 2010
Includes: Supplemental data
Journal Articles

An in vivo model to study and manipulate the hematopoietic stem cell niche

Free
Junhui Song, Mark J. Kiel, Zhou Wang, Jingcheng Wang, Russell S. Taichman, Sean J. Morrison, Paul H. Krebsbach
Journal: Blood
Blood (2010) 115 (13): 2592–2600.
https://doi.org/10.1182/blood-2009-01-200071
Published: 2010
Includes: Supplemental data
Journal Articles

Human and Rhesus Macaque Hematopoietic Stem Cells Are Not Enriched in the CD150+CD48- SLAM Population.

Free
Andre Larochelle, MD., Ph.D, Michael Savona, MD, Michael Wiggins, MD, Stephanie Anderson, Sean J Morrison, PhD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2009) 114 (22): 3531.
https://doi.org/10.1182/blood.V114.22.3531.3531
Published: 2009
Journal Articles

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems

Free
Boaz P. Levi, Ömer H. Yilmaz, Gregg Duester, Sean J. Morrison
Journal: Blood
Blood (2009) 113 (8): 1670–1680.
https://doi.org/10.1182/blood-2008-05-156752
Published: 2009
Includes: Supplemental data
Journal Articles

CD150 − cells are transiently reconstituting multipotent progenitors with little or no stem cell activity

Free
Mark J. Kiel, Omer H. Yilmaz, Sean J. Morrison
Journal: Blood
Blood (2008) 111 (8): 4413–4414.
https://doi.org/10.1182/blood-2007-12-129601
Published: 2008
Journal Articles

SLAM-Family Expression on Human Mobilized Peripheral Blood Progenitors.

Free
Michael R. Savona, MD, Mark J. Kiel, BS, Andrew D. Leavitt, MD, Sean J. Morrison, PhD
Journal: Blood
Blood (2006) 108 (11): 1675.
https://doi.org/10.1182/blood.V108.11.1675.1675
Published: 2006
Journal Articles

Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors

Free
Injune Kim, Shenghui He, Ömer H. Yilmaz, Mark J. Kiel, Sean J. Morrison
Journal: Blood
Blood (2006) 108 (2): 737–744.
https://doi.org/10.1182/blood-2005-10-4135
Published: 2006
Includes: Supplemental data
Journal Articles

SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity

Free
Ömer H. Yilmaz, Mark J. Kiel, Sean J. Morrison
Journal: Blood
Blood (2006) 107 (3): 924–930.
https://doi.org/10.1182/blood-2005-05-2140
Published: 2006
Journal Articles

CD144 (VE-cadherin) is transiently expressed by fetal liver hematopoietic stem cells

Free
Brief Report
Injune Kim, Ömer H. Yilmaz, Sean J. Morrison
Journal: Blood
Blood (2005) 106 (3): 903–905.
https://doi.org/10.1182/blood-2004-12-4960
Published: 2005