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Roland Jäger
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Journal Articles

Germline genetic factors influence the outcome of interferon-α therapy in polycythemia vera

Brief Report
Roland Jäger, Heinz Gisslinger, Elisabeth Fuchs, Edith Bogner, Jelena D. Milosevic Feenstra, Jakob Weinzierl, Fiorella Schischlik, Bettina Gisslinger, Martin Schalling, Michael Zörer, Kurt Krejcy, Christoph Klade, Robert Kralovics
Journal: Blood
Blood (2021) 137 (3): 387–391.
https://doi.org/10.1182/blood.2020005792
Published: 2021
Includes: Supplemental data
Journal Articles

Overexpression of PD-L1 Correlates with JAK2 -V617F Mutational Burden and Is Associated with Chromosome 9p Uniparental Disomy in MPN

Jelena D. Milosevic Feenstra, PhD, Fiorella Schischlik, PhD, Roland Jäger, PhD, Daniel Ivanov, MSc, Gregor Eisenwort, MD PhD, Alexandra Keller, PhD, Michael Schuster, PhD, Emir Hadzijusufovic, DVM, Maria-Theresa Krauth, MD, Robert Spörk, MSc, Bettina Gisslinger, MSc, Elisabeth Koller, MD, Michael Fillitz, MD, Michael Pfeilstocker, MD, Thamer Sliwa, MD, Felix Keil, MD, Christoph Bock, PhD, Heinz Gisslinger, MD, Robert Kralovics, PhD, Peter Valent, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24.
https://doi.org/10.1182/blood-2020-137447
Published: 2020
Journal Articles

Ifnα Attenuates the Disease Phenotype and Extends Survival in Mouse Models of MPN

Harini Nivarthi, PhD, Andrea Majoros, PhD, Eva Hug, PhD, Ruochen Jia, PhD, Sarada Achyutuni, Roland Jäger, PhD, Raimund Holly, Beatrice Grabner, Felix Rosebrock, Shin-Jye Lee, Chung-Wei Lee, Robert Kralovics, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 53.
https://doi.org/10.1182/blood-2020-138813
Published: 2020
Journal Articles

Co-Expression of JAK2-V617F and Calr-del52 In Vivo Enhances Myeloproliferative Phenotype in Mice and Does Not Influence Competitive Fitness of Hematopoietic Stem Cells

Andrea Majoros, PhD, Harini Nivarthi, PhD, Ruochen Jia, PhD, Roland Jäger, PhD, Sarada Achyutuni, Christina M. Schueller, Robert Kralovics, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-139996
Published: 2020
Journal Articles

Germline Genetic Factors Affecting Interferon Alpha Therapy in Polycythemia Vera

Roland Jäger, PhD, Elisabeth Fuchs, Edith Bogner, Jelena D. Milosevic Feenstra, PhD, Kurt Krejcy, MD, Christoph Klade, PhD, Michael Zoerer, PhD, Heinz Gisslinger, MD, Robert Kralovics, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1685.
https://doi.org/10.1182/blood-2019-130139
Published: 2019
Journal Articles

Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms

Fiorella Schischlik, Roland Jäger, Felix Rosebrock, Eva Hug, Michael Schuster, Raimund Holly, Elisabeth Fuchs, Jelena D. Milosevic Feenstra, Edith Bogner, Bettina Gisslinger, Martin Schalling, Elisa Rumi, Daniela Pietra, Gottfried Fischer, Ingrid Faé, Loan Vulliard, Jörg Menche, Torsten Haferlach, Manja Meggendorfer, Anna Stengel, Christoph Bock, Mario Cazzola, Heinz Gisslinger, Robert Kralovics
Journal: Blood
Blood (2019) 134 (2): 199–210.
https://doi.org/10.1182/blood.2019000519
Published: 2019
Includes: Supplemental data
Journal Articles

Mutational Landscape of the Transcriptome Offers a Rich Neoantigen Resource for Immunotherapy of Myeloproliferative Neoplasms

Fiorella Schischlik, MSc, Roland Jäger, PhD, Felix Rosebrock, Eva Hug, PhD, Michael Schuster, PhD, Raimund Holly, Elisabeth Fuchs, Jelena D. Milosevic Feenstra, PhD, Edith Bogner, Bettina Gisslinger, Martin Schalling, MSc, Elisa Rumi, MD, Daniela Pietra, PhD, Gottfried Fischer, MD, Ingrid Faé, Vulliard Loan, Jörg Menche, PhD, Torsten Haferlach, MD, Manja Meggendorfer, PhD, Anna Stengel, PhD, Christoph Bock, PhD, Mario Cazzola, Heinz Gisslinger, Robert Kralovics, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3058.
https://doi.org/10.1182/blood-2018-99-118049
Published: 2018
Journal Articles

Genomic Profiling of Blast Phase in Philadelphia-Negative Myeloproliferative Neoplasms

Elisa Roncoroni, Jelena D. Milosevic Feenstra, PhD, Elisa Rumi, MD, Daniela Pietra, PhD, Virginia Valeria Ferretti, Marta Bellini, MD, Chiara Cavalloni, MD, Ilaria Carola Casetti, MD, Roland Jäger, PhD, Edith Bogner, Michele Ciboddo, MD, Patrizia Zappasodi, MD, Cristina Picone, Laura Vanelli, Cesare Astori, MD, Robert Kralovics, PhD, Mario Cazzola, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1652.
https://doi.org/10.1182/blood.V130.Suppl_1.1652.1652
Published: 2017
Journal Articles

Impact of High Molecular Risk Mutations on Overall Survival in WHO-Defined Essential Thrombocythemia and Prefibrotic Primary Myelofibrosis

Heinz Gisslinger, Martin Schalling, Bettina Gisslinger, Roland Jäger, PhD, Edith Bogner, Ashot S Harutyunyan, PhD, Jelena D Milosevic Feenstra, Nicole C.C. Them, Maria-Theresa Krauth, MD, Leonhard Muellauer, MD, Juergen Thiele, MD PhD, Robert Kralovics
Journal: Blood
Blood (2016) 128 (22): 1931.
https://doi.org/10.1182/blood.V128.22.1931.1931
Published: 2016
Journal Articles

Monitoring Molecular Response, Minimal Residual Disease and Clonal Structures in Polycythemia Vera Patients Treated with Interferon Alpha

Roland Jäger, Edith Bogner, Kerstin Trenker, Michael Gurbisz, Bettina Gisslinger, Martin Schalling, Faith Hall-Glenn, Nicole C.C. Them, Christoph Klade, Heinz Gisslinger, Gregor Hoermann, Robert Kralovics
Journal: Blood
Blood (2016) 128 (22): 1944.
https://doi.org/10.1182/blood.V128.22.1944.1944
Published: 2016
Journal Articles

Germline RBBP6 mutations in familial myeloproliferative neoplasms

Clinical Trials & Observations
Ashot S. Harutyunyan, Roberto Giambruno, Christian Krendl, Alexey Stukalov, Thorsten Klampfl, Tiina Berg, Doris Chen, Jelena D. Milosevic Feenstra, Roland Jäger, Bettina Gisslinger, Heinz Gisslinger, Elisa Rumi, Francesco Passamonti, Daniela Pietra, André C. Müller, Katja Parapatics, Florian P. Breitwieser, Richard Herrmann, Jacques Colinge, Keiryn L. Bennett, Giulio Superti-Furga, Mario Cazzola, Emma Hammond, Robert Kralovics
Journal: Blood
Blood (2016) 127 (3): 362–365.
https://doi.org/10.1182/blood-2015-09-668673
Published: 2016
Includes: Supplemental data
Journal Articles

Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms

Clinical Trials & Observations
Jelena D. Milosevic Feenstra, Harini Nivarthi, Heinz Gisslinger, Emilie Leroy, Elisa Rumi, Ilyas Chachoua, Klaudia Bagienski, Blanka Kubesova, Daniela Pietra, Bettina Gisslinger, Chiara Milanesi, Roland Jäger, Doris Chen, Tiina Berg, Martin Schalling, Michael Schuster, Christoph Bock, Stefan N. Constantinescu, Mario Cazzola, Robert Kralovics
Journal: Blood
Blood (2016) 127 (3): 325–332.
https://doi.org/10.1182/blood-2015-07-661835
Published: 2016
Includes: Supplemental data
Journal Articles

Common Variation at 6q25.3 ( TULP4 ) Influences Risk for Arterial Thrombosis in Myeloproliferative Neoplasms

Roland Jäger, PhD, Ashot S Harutyunyan, PhD, Elisa Rumi, MD, Bettina Gisslinger, Martin Schalling, MSc, Virginia Ferretti, PhD, Daniela Pietra, PhD, Mario Cazzola, MD, Heinz Gisslinger, MD, Robert Kralovics, PhD
Journal: Blood
Blood (2015) 126 (23): 4088.
https://doi.org/10.1182/blood.V126.23.4088.4088
Published: 2015
Journal Articles

Whole Exome Sequencing Identifies Novel MPL and JAK2 M utations in Triple Negative Myeloproliferative Neoplasms

Jelena D Milosevic Feenstra, PhD, Harini Nivarthi, PhD, Heinz Gisslinger, MD, Emilie Leroy, Elisa Rumi, MD, Ilyas Chachoua, Klaudia Bagienski, Blanka Kubesova, MSc, Daniela Pietra, PhD, Bettina Gisslinger, Roland Jäger, PhD, Doris Chen, PhD, Tiina Berg, B.Sc., Martin Schalling, MSc, Michael Schuster, PhD, Christoph Bock, PhD, Stefan N. Constantinescu, MD PhD, Mario Cazzola, MD, Robert Kralovics, PhD
Journal: Blood
Blood (2015) 126 (23): 606.
https://doi.org/10.1182/blood.V126.23.606.606
Published: 2015
Journal Articles

Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression

Thorsten Klampfl, Ashot Harutyunyan, Tiina Berg, Bettina Gisslinger, Martin Schalling, Klaudia Bagienski, Damla Olcaydu, Francesco Passamonti, Elisa Rumi, Daniela Pietra, Roland Jäger, Lisa Pieri, Paola Guglielmelli, Ilaria Iacobucci, Giovanni Martinelli, Mario Cazzola, Alessandro M. Vannucchi, Heinz Gisslinger, Robert Kralovics
Journal: Blood
Blood (2011) 118 (1): 167–176.
https://doi.org/10.1182/blood-2011-01-331678
Published: 2011
Includes: Supplemental data
Journal Articles

Clonal analysis of deletions on chromosome 20q and JAK2 -V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2 -V617F

Franz X. Schaub, Roland Jäger, Renate Looser, Hui Hao-Shen, Sylvie Hermouet, François Girodon, Andre Tichelli, Heinz Gisslinger, Robert Kralovics, Radek C. Skoda
Journal: Blood
Blood (2009) 113 (9): 2022–2027.
https://doi.org/10.1182/blood-2008-07-167056
Published: 2009