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Paul W Buehler
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Journal Articles

Hemolysis, free hemoglobin toxicity, and scavenger protein therapeutics

Free
Florence Vallelian, Paul W. Buehler, Dominik J. Schaer
Journal: Blood
Blood (2022) 140 (17): 1837–1844.
https://doi.org/10.1182/blood.2022015596
Published: 2022
Journal Articles

The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease

Open Access
Naja Nyffenegger, Rahima Zennadi, Natarajaswamy Kalleda, Anna Flace, Giada Ingoglia, Raphael M. Buzzi, Cédric Doucerain, Paul W. Buehler, Dominik J. Schaer, Franz Dürrenberger, Vania Manolova
Journal: Blood
Blood (2022) 140 (7): 769–781.
https://doi.org/10.1182/blood.2021014716
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

A mechanistic investigation of thrombotic microangiopathy associated with IV abuse of Opana ER

Free
Ryan Hunt, Ayla Yalamanoglu, James Tumlin, Tal Schiller, Jin Hyen Baek, Andrew Wu, Agnes B. Fogo, Haichun Yang, Edward Wong, Peter Miller, Paul W. Buehler, Chava Kimchi-Sarfaty
Journal: Blood
Blood (2017) 129 (7): 896–905.
https://doi.org/10.1182/blood-2016-08-736579
Published: 2017
Includes: Supplemental data
Journal Articles

A Mechanistic Investigation of the TTP-like State Associated with Intravenous Abuse of Opana ® ER

Free
Ryan Hunt, MD, Ayla Yalamanoglu, MD, Jin Hyen Baek, PhD, Stephen Butler, MD, Tal Schiller, MD, Edward Wong, MD MA, Paul W Buehler, PhD, Chava Kimchi-Sarfaty, PhD
Journal: Blood
Blood (2015) 126 (23): 3521.
https://doi.org/10.1182/blood.V126.23.3521.3521
Published: 2015
Journal Articles

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Free
Dominik J. Schaer, Paul W. Buehler, Abdu I. Alayash, John D. Belcher, Gregory M. Vercellotti
Journal: Blood
Blood (2013) 121 (8): 1276–1284.
https://doi.org/10.1182/blood-2012-11-451229
Published: 2013
Journal Articles

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

Free
Paul W. Buehler, Bindu Abraham, Florence Vallelian, Charlotte Linnemayr, Claudia P. Pereira, John F. Cipollo, Yiping Jia, Malgorzata Mikolajczyk, Felicitas S. Boretti, Gabriele Schoedon, Abdu I. Alayash, Dominik J. Schaer
Journal: Blood
Blood (2009) 113 (11): 2578–2586.
https://doi.org/10.1182/blood-2008-08-174466
Published: 2009
Includes: Supplemental data
Journal Articles

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin

Free
Dominik J. Schaer, Christian A. Schaer, Paul W. Buehler, Robert A. Boykins, Gabriele Schoedon, Abdu I. Alayash, Andreas Schaffner
Journal: Blood
Blood (2006) 107 (1): 373–380.
https://doi.org/10.1182/blood-2005-03-1014
Published: 2006
Includes: Supplemental data