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Journal Articles

Ruxolitinib, a JAK1/2 Inhibitor, Is Efficacious in a Novel Humanized GvHD Model Characterized By Enhanced NK, NK-T and T-Cell Engraftment

Eduardo Huarte, PhD, Michael Peel, PhD, Philip Dube, PhD, Lynn Stephens, Becky Stewart, Brian Long, Philip Czerniak, Julian Oliver, PhD, Paul Smith, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-139805
Published: 2020
Journal Articles

Translationally Relevant Oral Ruxolitinib Dosing Reduces Inflammation and Ameliorates Disease in Murine Models of Hemophagocytic Lymphohistiocytosis

Eduardo Huarte, PhD, Michael Peel, PhD, Katherine Verbist, PhD, Brittany Fay, Sabrin Albeituni, PhD, Kim E. Nichols, MD, Paul Smith, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21.
https://doi.org/10.1182/blood-2020-139539
Published: 2020
Journal Articles

Bortezomib Consolidation Following Upfront ASCT for Multiple Myeloma Deepens Disease Response and MRD-Negative Rate without Compromising Response to Subsequent Bortezomib Salvage: Results of a Phase II Study

Oliver C Cohen, MBBS MRCP, Neil Rabin, Nicholas Counsell, Roger G Owen, MD PhD, Bilyana Popova, Oliver Schofield, Janet Lyons-Lewis, Andy Rawstron, Christopher Spence, Ruth Mary de Tute, PhD FRCPath, Derralynn Hughes, MRCP, MRCPath, DPhil, MA, Sally Moore, BSc, FRPATH, FRCP, MBBS, Paul Smith, PhD, Kwee L Yong
Journal: Blood
Blood (2016) 128 (22): 4508.
https://doi.org/10.1182/blood.V128.22.4508.4508
Published: 2016
Journal Articles

SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction

Essam Ghazaly, MD PhD, Paul Smith, PhD, Chathunissa Gnanaranjan, MSc, Bryan D Young, BSc, PhD, Simon Joel, PhD, John G. Gribben, MD DSc, David C Taussig, PhD MRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 5324.
https://doi.org/10.1182/blood.V124.21.5324.5324
Published: 2014
Journal Articles

Feasibility Of Pegylated-Asparaginase (PEG-ASP) During Induction In Adults With Acute Lymphoblastic Leukaemia (ALL): Results From The UK Phase 3 Multicentre Trial UKALL 14

Bella Patel, MB, BS, MD, A Kirkwood, Aditi Dey, Clare Rowntree, Andrew McMillan, FRCP, FRCPath, PhD, David Marks, MD, PhD, Tobias Menne, Paul Smith, PhD, Simon Purnell, Lynda Micklewright, Adele K Fielding, MB, BS, PhD
Journal: Blood
Blood (2013) 122 (21): 3900.
https://doi.org/10.1182/blood.V122.21.3900.3900
Published: 2013
Journal Articles

Young Adults Aged 18 to 30 Years with Hodgkin Lymphoma Can Tolerate a Modified Version of the Combined Modality German Paediatric HD95 Protocol with Minimal Neurotoxicity and Excellent Outcome. Results of the UK NCRN 18–30 Study (CRUK/08/012)

Kirit M Ardeshna, MD, Peter Hoskin, Paul Smith, PhD, Nicholas Chadwick, Nivette Braganca, Wai-Lup Wong, MD, Irfan Kayani, Bal Sanghera, Patricia Diez, Helen Lucraft, Andrew Jack, PhD, MB, Christopher J McNamara, George Mikhaeel, MD, Scott Marshall, MD, Ruth Pettengell, Robert E. Marcus, MBBS, FRCP, FRCPath, Anton Kruger, David C Linch, MD FMedSci
Journal: Blood
Blood (2012) 120 (21): 1621.
https://doi.org/10.1182/blood.V120.21.1621.1621
Published: 2012
Journal Articles

A Phase 1 Trial of Escalating High Dose Methotrexate Supported by Glucarpidase to Treat Patients with Primary Central Nervous System Lymphoma (PCNSL). (CRUK/08/010)

Roderick J. Johnson, MD, Andrew Davies, MD, Siow-Ming Lee, MD, Dianne Gilson, MD, Paul Smith, PhD, Wendi Qian, Nivette Braganca, Nadjet El-mehidi, Peter Johnson
Journal: Blood
Blood (2012) 120 (21): 4850.
https://doi.org/10.1182/blood.V120.21.4850.4850
Published: 2012
Journal Articles

Genome Wide Study of DNA Methylation In AML

Marwa Saied, MBCHB, MD, Sabah Khaled, PhD, Thomas Down, PhD, Jacek Marzec, PhD, Paul Smith, PhD, Silvana Debernardi, PhD, BSc, Bryan D Young, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 3618.
https://doi.org/10.1182/blood.V116.21.3618.3618
Published: 2010