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Paul Brent Ferrell
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Journal Articles

The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NFκB signaling

Open Access
Paran Goel, Sajesan Aryal, Alana M. Franceski, Valeriya Kuznetsova, Amanda Fernandes De Oliveira Costa, Francesca Luca, Ashley N Connelly, Daniel W Phillips, Caroline C Ennis, Brittany M. Curtiss, Sourajeet Karfa, Brittany L Crown, Christina R Larson, Estelle Carminita, Virginia Camacho, Doug Welsch, Changde Cheng, Asumi Yokota, Isidoro Cobo, Hideyo Hirai, Rui Lu, Ravi Bhatia, Pran K Datta, Paul Brent Ferrell, Jr., Robert S. Welner
Journal: Blood
Blood blood.2024028199.
https://doi.org/10.1182/blood.2024028199
Published: 2025
Includes: Supplemental data
Journal Articles

Multi-Recombinase Mouse Models of Flt3-Driven Leukemia Identifies Distinct Trajectories of Mutational Cooperativity and Leukemic Transformation

Free
Robert L. Bowman, Tanmay Mishra, Shira E. Eisman, Louise Cai, Wenbin Xiao, Michael R. Waarts, Pablo Sanchez Vela, Inés Fernández-Maestre, Isabelle S. Csete, Chad R. Potts, Matthew T. Jenkins, Linde A. Miles, Jennifer J. Trowbridge, Paul Brent Ferrell, Jr., Ross L. Levine
Journal: Blood
Blood (2021) 138 (Supplement 1): 2220.
https://doi.org/10.1182/blood-2021-149846
Published: 2021
Journal Articles

Single Cell Signaling Responses Stratify Immune and Leukemia Cell Populations in Acute Myeloid Leukemia

Free
Kathryn I Sunthankar, MD, Benjamin J Reisman, BS, Candace H Cote, BS, Paul Brent Ferrell, Jr., MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2680.
https://doi.org/10.1182/blood-2019-129602
Published: 2019
Journal Articles

Venetoclax-Based Salvage Therapy for Post-Hematopoietic Cell Transplantation Relapse in Acute Myeloid Leukemia

Free
Michael T Byrne, DO, Nathalie Danielson, MSN, Adrianne Rasche, MSN, Rachel Hammers, MSN, Kathryn A Culos, PharmD, Katie S Gatwood, PharmD, Houston Wyatt, PharmD, Kristin Fogo, BSN, Bhagirathbhai Dholaria, MBBS, Brian G Engelhardt, MD, Paul Brent Ferrell, Jr., MD, Madan Jagasia, MBBS, MS, MMHC, Adetola A. Kassim, MDMS, Sanjay R Mohan, MD MSCI, Bipin N. Savani, MD, Stephen A. Strickland, MD, Salyka M. Sengsayadeth, MD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2643.
https://doi.org/10.1182/blood-2019-129146
Published: 2019
Journal Articles

Olutasidenib (FT-2102), an IDH1m Inhibitor As a Single Agent or in Combination with Azacitidine, Induces Deep Clinical Responses with Mutation Clearance in Patients with Acute Myeloid Leukemia Treated in a Phase 1 Dose Escalation and Expansion Study

Free
Justin M. Watts, MD, Maria R. Baer, MD, Jay Yang, MD, Thomas Prebet, MD PhD, Sangmin Lee, MD, Gary J. Schiller, MD, Shira Dinner, MD, Arnaud Pigneux, Pau Montesinos, MD PhD, Eunice S. Wang, MD, Karen Seiter, MD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Stephane De Botton, Montserrat Arnan Sangerman, William B. Donnellan, MD, Brian A Jonas, MD PhD, Paul Brent Ferrell, Jr., MD, Kim-Hien Dao, DO, PhD, Patrick Kelly, MD, Jennifer Sweeney, Sanjeev Forsyth, Sylvie Guichard, Julie Brevard, Patrick Henrick, Hesham Mohamed, MD, Jorge E. Cortes, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 231.
https://doi.org/10.1182/blood-2019-123920
Published: 2019
Journal Articles

FT-2102, an IDH1m Inhibitor, in Combination with Azacitidine in Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Ayndrome (MDS): Results from a Phase 1 Study

Free
Jorge E. Cortes, MD, Justin Watts, MD, Thomas Prebet, MD PhD, Gary J. Schiller, MD, Sangmin Lee, MD, Jay Yang, MD, Eunice S. Wang, MD, Shira Dinner, MD, Paul Brent Ferrell, Jr., MD, Will Donnellan, MD, Brian A. Jonas, MD PhD, Andrew H Wei, MBBS, PhD, Pau Montesinos, MD PhD, Montserrat Arnan Sangerman, MD, Patrick Kelly, MD, Ping Li, PhD, Jennifer Sweeney, Courtney Watson, Hesham Mohamed, MD, Maria R. Baer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1452.
https://doi.org/10.1182/blood-2018-99-114126
Published: 2018
Journal Articles

Phase 1 Study of the IDH1m Inhibitor FT-2102 As a Single Agent in Patients with IDH1 m Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Free
Justin Watts, MD, Maria R. Baer, MD, Jay Yang, MD, Shira Dinner, MD, Sangmin Lee, MD, Karen Seiter, MD, Thomas Prebet, MD PhD, Gary J. Schiller, MD, Paul Brent Ferrell, Jr., MD, Kim-Hien Dao, DO, PhD, Hagop M. Kantarjian, MD, Patrick Kelly, MD, Ping Li, PhD, Jennifer Sweeney, Courtney Watson, Hesham Mohamed, MD, Jorge E. Cortes, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1453.
https://doi.org/10.1182/blood-2018-99-114263
Published: 2018
Journal Articles

IDH2 Mutations Induce Altered STAT Signaling and Cytokine Responses Which Are Restored By Enasidenib

Free
Kathryn S Ivy, BA, Candace H Cote, BS, Paul Brent Ferrell, Jr., MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1468.
https://doi.org/10.1182/blood-2018-99-117783
Published: 2018
Journal Articles

Expression of S100A9 in Bone Marrow Cells Differentiates Refractory Cytopenia with Multilineage Dysplasia (RCMD) from Refractory Anemia with Excess Blasts (RAEB) and Acute Myeloid Leukemia (AML)

Free
Paul Brent Ferrell, Jr., MD, Caroline R. Maier, BS, Mikael Roussel, MD PhD, Michael R. Savona, MD, Jonathan Michael Irish, PhD
Journal: Blood
Blood (2016) 128 (22): 4303.
https://doi.org/10.1182/blood.V128.22.4303.4303
Published: 2016
Journal Articles

Mutational Burden in Acute Myeloid Leukemia Is Largely Age Dependent

Free
Aaron C. Shaver, MD PhD, Adam C. Seegmiller, MD PhD, Stephen A. Strickland, MD, Robert D. Daber, PhD, Sanjay R. Mohan, MD, Paul Brent Ferrell, Jr., MD, Cindy Vnencak-Jones, PhD, David R. Head, MD, Annette S. Kim, MD PhD, Mary M. Zutter, MD, Michael R. Savona, MD
Journal: Blood
Blood (2015) 126 (23): 2605.
https://doi.org/10.1182/blood.V126.23.2605.2605
Published: 2015
Journal Articles

Dissecting Signaling Network Responses to PAK4 Allosteric Modulators (PAMs) in Cell Subsets within Primary Human Acute Myeloid Leukemia Samples

Free
Paul Brent Ferrell, Jr., MD, William Senapedis, PhD, Alexander Cook, Erkan Baloglu, PhD, Yosef Landesman, PhD, Jonathan Michael Irish, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2015) 126 (23): 3686.
https://doi.org/10.1182/blood.V126.23.3686.3686
Published: 2015
Journal Articles

Mass Cytometry of Acute Myeloid Leukemia Captures Early Therapy Response in Rare Cell Subsets

Free
Paul Brent Ferrell, MD, Kirsten E. Diggins, Hannah G. Polikowsky, Jonathan M. Irish, PhD
Journal: Blood
Blood (2014) 124 (21): 2381.
https://doi.org/10.1182/blood.V124.21.2381.2381
Published: 2014