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Michael Kauffman, MD, Ph.D.
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Journal Articles

Prognostic Impact and Targeting of CRM1 in Acute Myeloid Leukemia

Free
Kensuke Kojima, MD, PhD, Steven M. Kornblau, MD, PhD, Vivian Ruvolo, Seshagiri Duvvuri, Richard E Davis, MD, Min Zhang, Ph.D., Zhiqiang Wang, Ph.D., Kevin R. Coombes, PhD, Nianxiang Zhang, Yi Hua Qiu, MD, Jared K. Burks, Peter P. Ruvolo, PhD, Sharon Shacham, PhD MBA, Michael Kauffman, MD, Ph.D., Michael Andreeff, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 870.
https://doi.org/10.1182/blood.V120.21.870.870
Published: 2012
Journal Articles

Nuclear Export (Karyopherin) Inhibitors: A Novel Therapeutic Strategy for Treating Blast Crisis Chronic Myelogenous Leukemia (CML) and Philadelphia-Positive (Ph + ) Acute Lymphoblastic Leukemia (ALL) Through Interference with hnRNP Nucleocytoplasmic Shuttling and Rescue of Protein Phosphatase 2A (PP2A) Tumor Suppressor Activity,

Free
Christopher J Walker, Joshua J Oaks, Ramasamy Santhanam, Ph.D, Paolo Neviani, PhD, Jason G Harb, Ph.D, Carolyn Paisie, B.S., Guido Marcucci, MD, Sharon Shacham, PhD, Michael Kauffman, MD, Ph.D., Danilo Perrotti, MD, Ph.D
Journal: Blood
Blood (2011) 118 (21): 3758.
https://doi.org/10.1182/blood.V118.21.3758.3758
Published: 2011
Journal Articles

KPT-SINE, a Potent, Small Molecule Inhibitor of CRM1-Dependent Nuclear-Cytoplasmic Shuttling, with Potent Activity Against T-ALL and AML

Free
Julia Etchin, PhD, Alex Kentsis, MD, PhD, Takaomi Sanda, MD, PhD, Andrew L. Kung, MD, PhD, Richard M. Stone, MD, Dilara McCauley, Michael Kauffman, MD, Ph.D., Sharon Shacham, PhD, Thomas Look, MD
Journal: Blood
Blood (2011) 118 (21): 2622.
https://doi.org/10.1182/blood.V118.21.2622.2622
Published: 2011
Journal Articles

CRM1/XPO1 Represents a Promising Therapeutic Target for Treatment of Chronic Lymphocytic Leukemia

Free
Rosa Lapalombella, PhD, Caroline Berglund, Emilia Mahoney, MD, PhD, Katie Williams, Shruti Jha, Asha Ramanunni, MD, Vincent Sandanayaka, Sharon Shechter, Dilara McCauley, Sharon Shacham, PhD, Michael Kauffman, MD, Ph.D., John C. Byrd, MD
Journal: Blood
Blood (2011) 118 (21): 232.
https://doi.org/10.1182/blood.V118.21.232.232
Published: 2011
Journal Articles

Development of a Novel Small Molecule CRM-1 Inhibitor for Non Hodgkin's Lymphoma

Free
Asfar Sohail Azmi, Research Associate, Ayad Al-Katib, MD, FACP, Amro Aboukameel, RA, Michael Kauffman, MD, Ph.D., Dilara McCauley, Research Associate, Ramzi Mohammad, PhD, Sharon Shacham, PhD
Journal: Blood
Blood (2011) 118 (21): 598.
https://doi.org/10.1182/blood.V118.21.598.598
Published: 2011