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Matthew D Keller
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Journal Articles

Type II Inhibition of JAK2 with NVP-CHZ868 Reverses Type I JAK Inhibitor Persistence and Demonstrates Increased Efficacy in MPN Models

Free
Sara C Meyer, MD PhD, Matthew D Keller, BS, Priya Koppikar, PhD, Olga A Guryanova, MD PhD, Maria Kleppe, PhD, Anna Sophia McKenney, MPH, William R Sellers, MD, Francesco Hofmann, PhD, Fabienne Baffert, Christoph Gaul, PhD, Thomas Radimerski, PhD, Ross L Levine, MD
Journal: Blood
Blood (2014) 124 (21): 160.
https://doi.org/10.1182/blood.V124.21.160.160
Published: 2014
Journal Articles

Mathematical Optimization of JAK Inhibitor Dose and Scheduling for MPN Patients

Free
Kaitlyn R Shank, B.S., Priya Koppikar, PhD, Neha Bhagwat, PhD, Matthew D Keller, B.S., Franziska Michor, PhD, Ross L Levine, MD, Laura De Vargas Roditi, PhD
Journal: Blood
Blood (2014) 124 (21): 911.
https://doi.org/10.1182/blood.V124.21.911.911
Published: 2014
Journal Articles

Conditional Loss of Dnmt3a Results in Myeloproliferation and Liver-Specific Myeloid Expansion

Free
Olga A Guryanova, MD PhD, Yen Lieu, PhD, Kaitlyn R Shank, B.S., Sharon Rivera, PhD, Francine E Garrett-Bakelman, MD PhD, Jacob Glass, MD PhD, Matthew D Keller, B.S., Suveg Pandey, B.S., Daniel Tovbin, Abby R Weinstein, Julie Teruya-Feldstein, MD, Omar Abdel-Wahab, MD, Christopher E Mason, PhD, Ari M Melnick, MD, Siddhartha Mukherjee, MD PhD, Ross L. Levine, MD
Journal: Blood
Blood (2014) 124 (21): 364.
https://doi.org/10.1182/blood.V124.21.364.364
Published: 2014
Journal Articles

Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis

Free
Brief Report
Sara C. Meyer, Matthew D. Keller, Brittany A. Woods, Lindsay M. LaFave, Lennart Bastian, Maria Kleppe, Neha Bhagwat, Sachie Marubayashi, Ross L. Levine
Journal: Blood
Blood (2014) 124 (14): 2280–2284.
https://doi.org/10.1182/blood-2014-03-560441
Published: 2014
Includes: Supplemental data
Journal Articles

Improved Efficacy Of Combination Of JAK2 and Hedgehog Inhibitors In Myelofibrosis

Free
Neha Bhagwat, B.S., Matthew D Keller, B.S., Raajit K. Rampal, M.D., Ph.D., Kaitlyn Shank, B.S., Elisa de Stanchina, PhD, Kristine Rose, PhD, Dereck Amakye, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 666.
https://doi.org/10.1182/blood.V122.21.666.666
Published: 2013