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Journal Articles

Genome Wide Association Analysis of Iron Overload in the Trans-Omics for Precision Medicine (TOPMed) Sickle Cell Disease Cohorts

Blood (2020) 136 (Supplement 1): 52.

https://doi.org/10.1182/blood-2020-142809

Published: 2020

Journal Articles

Loss of FXR Signaling Promotes Chronic Liver Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Mark T Gladwin, MD, Prithu Sundd, PhD, Tirthadipa Pradhan

Blood (2020) 136 (Supplement 1): 16.

https://doi.org/10.1182/blood-2020-143330

Published: 2020

Journal Articles

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

Solomon Johnson, MS, Victor R. Gordeuk, MD, Roberto Machado, MD, J Simon R Gibbs, Mariana Hildesheim, MS, Jane A. Little, MD, Gregory J Kato, MD, Mark T Gladwin, MD, Seyed Mehdi Nouraie, PhD MD

Blood (2020) 136 (Supplement 1): 59–60.

https://doi.org/10.1182/blood-2020-136393

Published: 2020

Journal Articles

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Katherine C Wood, PhD, Heidi M Schmidt, Scott Hahn, MS, Subramaniam Sanker, PhD, Samit Ghosh, PhD, Solomon Fiifi Ofori-Acquah, PhD, Seyed Mehdi Nouraie, MD PhD, Mark T Gladwin, MD, Adam C Straub, PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-142076

Published: 2020

Journal Articles

Integrin αIIbβ3 Regulates Platelet-Procoagulant Activity in the Lung

Tomasz Brzoska, PhD, Tomasz W. Kaminski, PharmD, Ravi Vats, MSc, Egemen Tutuncuoglu, MSc, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2020) 136 (Supplement 1): 32.

https://doi.org/10.1182/blood-2020-142503

Published: 2020

Journal Articles

Impaired Hepcidin Metabolism Promotes Hemolysis Induced Hepatobiliary Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Prithu Sundd, PhD, Mark T Gladwin, MD, Tirthadipa Pradhan

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-143357

Published: 2020

Journal Articles

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Stevan P. Tofovic, Edwin K. Jackson, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 2266.

https://doi.org/10.1182/blood-2019-130882

Published: 2019

Journal Articles

Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia

Santosh L. Saraf, MD, Vimal K. Derebail, MD, Xu Zhang, PhD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Jane A. Little, MD

Blood (2019) 134 (Supplement_1): 2268.

https://doi.org/10.1182/blood-2019-124737

Published: 2019

Journal Articles

Risk Factors for Kidney Disease in Hb SC and Hb Sβ + -Thalassemia Sickle Cell Disease

Mandella Mensah, Binal N. Shah, Xu Zhang, PhD, Jin Han, PharmD, PhD, Michel Gowhari, DO, Robert E. Molokie, MD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Santosh L. Saraf, MD

Blood (2019) 134 (Supplement_1): 2299.

https://doi.org/10.1182/blood-2019-128668

Published: 2019

Journal Articles

Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice

Tomasz W. Kaminski, PharmD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 1043.

https://doi.org/10.1182/blood-2019-130471

Published: 2019

Journal Articles

Circulating Neutrophil Extracellular Traps in the Pathogenesis of Acute Chest Syndrome of Sickle Cell Disease

Ravi Vats, MSc, Egemen Tutuncuoglu, MSc, Jesus Tejero, PhD, Cheryl A Hillery, MD, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 3556.

https://doi.org/10.1182/blood-2019-130574

Published: 2019

Journal Articles

Smooth Muscle Cytochrome b5 Reductase 3 Deficiency Accelerates Pulmonary Hypertension Development in Sickle Cell Mice

Katherine Wood, PhD BA, Brittany Durgin, PhD, Heidi M Schmidt, BSE, Scott Hahn, Jeffrey Baust, Tim Bachman, Dario A. Vitturi, PhD, Samit Ghosh, Solomon Fiifi Ofori-Acquah, Ana Mora, MD, Mark T Gladwin, MD, Adam Straub, PhD

Blood (2019) 134 (Supplement_1): 3619.

https://doi.org/10.1182/blood-2019-124159

Published: 2019

Journal Articles

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

Tirthadipa Pradhan, Prithu Sundd, PhD, Mark T Gladwin, MD, Satdarshan Pal Monga, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 3536.

https://doi.org/10.1182/blood-2019-131915

Published: 2019

Journal Articles

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Tomasz Brzoska, PhD, Margaret F. Bennewitz, PhD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Matthew D Neal, MD, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 976.

https://doi.org/10.1182/blood-2019-130592

Published: 2019

Journal Articles

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Tirthadipa Pradhan, Prithu Sundd, PhD, Satdarshan Pal Monga, Mark T Gladwin, MD, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 958.

https://doi.org/10.1182/blood-2019-131921

Published: 2019

Journal Articles

Evaluation of the Functional Effects of an African American Glucose-6-Phosphate Dehydrogenase (G6PD) Polymorphism (Val68Met) on RBC Hemolytic Propensity and Post-Transfusion Recovery in a Humanized Mouse Model

Ling Wang, MD PhD, Benjamin Zuchelkowski, Derek Sinchar, Minying Yang, Sebastien Gingras, Tamir Kanias, PhD, Janet S Lee, Daniel Kim-Shapiro, Grier Page, PhD BS, MS, Mark T Gladwin, MD

Blood (2019) 134 (Supplement_1): 102.

https://doi.org/10.1182/blood-2019-124926

Published: 2019

Journal Articles

Clinical and Laboratory Predictors of 30-Day Hospital Readmission Risk in Adult Patients with Sickle Cell Disease

Seyed Mehdi Nouraie, PhD MD, Melissa Saul, MS, Enrico M Novelli, MD MS, Gregory J. Kato, MD, Mark T Gladwin, MD

Blood (2018) 132 (Supplement 1): 2384.

https://doi.org/10.1182/blood-2018-99-115248

Published: 2018

Journal Articles

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Bin Sun, PhD, Valerie Miller, MS, Karin P Potoka, MD, Yukio Nakamura, MD PhD, Mark T Gladwin, MD, Grant C. Bullock, MD PhD

Blood (2018) 132 (Supplement 1): 1060.

https://doi.org/10.1182/blood-2018-99-120306

Published: 2018

Journal Articles

Regulatory Genetic Variation at the S100B Gene Associates with Vaso-Occlusive Manifestations in Sickle Cell Disease

Xu Zhang, PhD, Wei Zhang, PhD, Santosh L. Saraf, MD, Sergei Nekhai, PhD, Mark T Gladwin, MD, Roberto Machado, Victor R. Gordeuk, MD

Blood (2018) 132 (Supplement 1): 1063.

https://doi.org/10.1182/blood-2018-99-115395

Published: 2018

Journal Articles

Neutrophil Extracellular Traps Promote Lung Arteriole Occlusion in Sickle Cell Disease

Ravi Vats, MSc, Margaret F. Bennewitz, PhD, Maritza Ann Jimenez, BS, Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Jesus Tejero, PhD, Cheryl Hillery, MD, Gregory J. Kato, MD, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2017) 130 (Supplement 1): 2243.

https://doi.org/10.1182/blood.V130.Suppl_1.2243.2243

Published: 2017

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Genome Wide Association Analysis of Iron Overload in the Trans-Omics for Precision Medicine (TOPMed) Sickle Cell Disease Cohorts

Loss of FXR Signaling Promotes Chronic Liver Injury in Sickle Cell Disease

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Integrin αIIbβ3 Regulates Platelet-Procoagulant Activity in the Lung

Impaired Hepcidin Metabolism Promotes Hemolysis Induced Hepatobiliary Injury in Sickle Cell Disease

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia

Risk Factors for Kidney Disease in Hb SC and Hb Sβ + -Thalassemia Sickle Cell Disease

Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice

Circulating Neutrophil Extracellular Traps in the Pathogenesis of Acute Chest Syndrome of Sickle Cell Disease

Smooth Muscle Cytochrome b5 Reductase 3 Deficiency Accelerates Pulmonary Hypertension Development in Sickle Cell Mice

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Evaluation of the Functional Effects of an African American Glucose-6-Phosphate Dehydrogenase (G6PD) Polymorphism (Val68Met) on RBC Hemolytic Propensity and Post-Transfusion Recovery in a Humanized Mouse Model

Clinical and Laboratory Predictors of 30-Day Hospital Readmission Risk in Adult Patients with Sickle Cell Disease

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Regulatory Genetic Variation at the S100B Gene Associates with Vaso-Occlusive Manifestations in Sickle Cell Disease

Neutrophil Extracellular Traps Promote Lung Arteriole Occlusion in Sickle Cell Disease

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