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Journal Articles

A multiomics approach reveals novel regulators of plasma factor V levels, highlighting CLEC4M as a clearance receptor

Available to Purchase
Gaëlle Munsch, Adarsh K. Mohapatra, Astrid van Hylckama Vlieg, Marcus E. Kleber, Angel Martinez-Perez, Ngoc-Quynh Le, Kristian Dalsbø Hindberg, Philip Dusart, Marine Germain, Florian Thibord, Jean-François Deleuze, Graciela E. Delgado, Louisa Goumidi, Pierre Suchon, Noémie Saut, Juan-Carlos Souto, Lynn M. Butler, Jose-Manuel Soria, John-Bjarne Hansen, Winfried März, Frits R. Rosendaal, Elisabetta Castoldi, Franck Peiretti, Maria Sabater-Lleal, David-Alexandre Trégouët, Pierre-Emmanuel Morange
Journal: Blood
Blood (2025) 146 (5): 628–637.
https://doi.org/10.1182/blood.2024027006
Published: 2025
Includes: Supplemental data
Journal Articles

CCR2 Cooperatively Regulates Hematopoietic Stem Cell Homing to the Bone Marrow

Free
Stephanie N Hurwitz, Danielle R Kobulsky, Seul K Jung, Jason M Butler, Peter Kurre
Journal: Blood
Blood (2024) 144 (Supplement 1): 2021.
https://doi.org/10.1182/blood-2024-199266
Published: 2024
Journal Articles

Netrin-1 Rejuvenates the Aged Hematopoietic Stem Cell Niche By Restoring the DNA Damage Response

Free
Pradeep Ramalingam, Michael Poulos, Jason M Butler
Journal: Blood
Blood (2022) 140 (Supplement 1): 8623.
https://doi.org/10.1182/blood-2022-167869
Published: 2022
Journal Articles

Sickle Cell Disease Compromises the Hematopoietic Stem Cells Bone Marrow Niche with Age

Free
Mahmoud Dabbah, Aditya Barve, Emilia Kooienga, Zakiya Kelley, Jason M Butler, Marta Derecka, Shannon McKinney-Freeman
Journal: Blood
Blood (2022) 140 (Supplement 1): 8622.
https://doi.org/10.1182/blood-2022-164738
Published: 2022
Journal Articles

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate

Free
Reiner K. Mailer, Mikel Allende, Marco Heestermans, Michaela Schweizer, Carsten Deppermann, Maike Frye, Giordano Pula, Jacob Odeberg, Mathias Gelderblom, Stefan Rose-John, Albert Sickmann, Stefan Blankenberg, Tobias B. Huber, Christian Kubisch, Coen Maas, Stepan Gambaryan, Dmitri Firsov, Evi X. Stavrou, Lynn M. Butler, Thomas Renné
Journal: Blood
Blood (2021) 137 (10): 1392–1405.
https://doi.org/10.1182/blood.2019004617
Published: 2021
Includes: Supplemental data
Journal Articles

Inhibition of Endothelial mTOR Drives Hematopoietic Stem Cell Aging

Free
Jason M. Butler, PhD, Pradeep Ramalingam, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1289.
https://doi.org/10.1182/blood-2018-99-117710
Published: 2018
Journal Articles

Endothelial MAPK Activation Disrupts Hematopoiesis By Depleting Plasma SCGF

Free
Jason M. Butler, PhD, Pradeep Ramalingam, MD, Elisa Lazzari, PhD, Michael Poulos, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1290.
https://doi.org/10.1182/blood-2018-99-117467
Published: 2018
Journal Articles

Single-Cell Characterization of the HSC-Supportive Bone Marrow Vascular Microenvironment

Free
Michael Poulos, PhD, David Redmond, PhD, Michael Gutkin, MS, Pradeep Ramalingam, MD, Jason M. Butler, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2577.
https://doi.org/10.1182/blood-2018-99-120339
Published: 2018
Journal Articles

Aging of the Vascular Niche Enhances Leukemia-Initiating Cell Metabolic Switch

Free
Elisa Lazzari, PhD, Pradeep Ramalingam, MD, Michael G. Poulos, PhD, Jason M. Butler, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 871.
https://doi.org/10.1182/blood-2018-99-115019
Published: 2018
Journal Articles

De-Escalation of Antimicrobials in Adult Hematopoietic Cell Transplantation Recipients with Febrile Neutropenia of Unknown Origin

Free
Megan M. Petteys, PharmD, Ekaterina Kachur, PharmD, Kelly E. Pillinger, PharmD, Jiaxian He, MS, James T. Symanowski, PhD, Candace M. Butler, MSPH, Lynn S. Sanders, MSN, RN, OCN, Nilanjan Ghosh, MD PhD, Michael R. Grunwald, MD, Belinda Rene Avalos, MD, Saad Z. Usmani, MD, Edward A. Copelan, MD, Zainab Shahid, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2079.
https://doi.org/10.1182/blood-2018-99-117148
Published: 2018
Journal Articles

Higher Incidence of Hemorrhagic Cystitis after Haploidentical Compared to Matched Sibling Donor Transplantation

Free
Srinivasa Reddy Sanikommu, MD, Olivia Copelan, BA, Jiaxian He, MS, Candace M. Butler, MSPH, Michael R. Grunwald, MD, Nilanjan Ghosh, MD PhD, Jing Ai, MD, Thomas G. Knight, MD, Brittany Ragon, MD, Ryan Jacobs, MD, Bei Hu, Saad Z. Usmani, MD, James T Symanowski, PhD, Zainab Shahid, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3380.
https://doi.org/10.1182/blood-2018-99-119612
Published: 2018
Journal Articles

Mechanisms Governing Endogenous Thymic Regeneration

Free
Tobias Wertheimer, Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Kirsten Cooper, Katja J Ottmüller, Zeinab Mokthari, Jason M. Butler, PhD, Shahin Rafii, MD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 66.
https://doi.org/10.1182/blood.V130.Suppl_1.66.66
Published: 2017
Journal Articles

PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study

Free
e-blood
Maria Bruzelius, Maria Jesus Iglesias, Mun-Gwan Hong, Laura Sanchez-Rivera, Beata Gyorgy, Juan Carlos Souto, Mattias Frånberg, Claudia Fredolini, Rona J. Strawbridge, Margareta Holmström, Anders Hamsten, Mathias Uhlén, Angela Silveira, Jose Manuel Soria, David M. Smadja, Lynn M. Butler, Jochen M. Schwenk, Pierre-Emmanuel Morange, David-Alexandre Trégouët, Jacob Odeberg
Journal: Blood
Blood (2016) 128 (23): e59–e66.
https://doi.org/10.1182/blood-2016-05-711846
Published: 2016
Includes: Supplemental data
Journal Articles

Direct Conversion of Adult Endothelial Cells into Immunecompetent Long-Term Engraftable Clinically Scalable Hematopoietic Stem Cells: Pathway to Therapeutic Translation

Free
Raphael Lis, PhD, Charles Harrasch, Michael Gustave Poulos, PhD, Jose Gabriel Duran, William Schachterle, PhD, Michael Ginsberg, PhD, Arash Rafii, Koji Shido, Nancy A. Speck, PhD, Jason M. Butler, PhD, Joseph M. Scandura, MD PhD, Shahin Rafii
Journal: Blood
Blood (2016) 128 (22): 372.
https://doi.org/10.1182/blood.V128.22.372.372
Published: 2016
Journal Articles

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome

Free
Wesley J. Woollard, Venu Pullabhatla, Anna Lorenc, Varsha M. Patel, Rosie M. Butler, Anthony Bayega, Nelema Begum, Farrah Bakr, Kiran Dedhia, Joshua Fisher, Silvia Aguilar-Duran, Charlotte Flanagan, Aria A. Ghasemi, Ricarda M. Hoffmann, Nubia Castillo-Mosquera, Elisabeth A. Nuttall, Arisa Paul, Ceri A. Roberts, Emmanouil G. Solomonidis, Rebecca Tarrant, Antoinette Yoxall, Carl Z. Beyers, Silvia Ferreira, Isabella Tosi, Michael A. Simpson, Emanuele de Rinaldis, Tracey J. Mitchell, Sean J. Whittaker
Journal: Blood
Blood (2016) 127 (26): 3387–3397.
https://doi.org/10.1182/blood-2016-02-699843
Published: 2016
Includes: Supplemental data
Journal Articles

Vascular Niche-Derived Angiocrine Factors Specify and Maintain Hematopoietic Stem Cells

Free
Shahin Rafii, MD, Jason M. Butler, PhD, Ginsberg Michael, PhD, Jennifer L Gori, PhD, Hans-Peter Kiem, MD, Scandura Jospeh, MD PhD
Journal: Blood
Blood (2015) 126 (23): SCI-25.
https://doi.org/10.1182/blood.V126.23.SCI-25.SCI-25
Published: 2015
Journal Articles

Rejuvenation of Aged Vascular Niches to Enhance Hematopoietic Function

Free
Michael Gustave Poulos, PhD, Michael Gutkin, M.S., Christopher Y. Park, MD, PhD, Jason M. Butler, PhD
Journal: Blood
Blood (2015) 126 (23): 781.
https://doi.org/10.1182/blood.V126.23.781.781
Published: 2015
Journal Articles

Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells

Free
Tomer Itkin, PhD, Shiri Gur Cohen, PhD, Joel A. Spencer, PhD, Amir Schajnovitz, Saravana K. Ramasamy, PhD, Anjali P. Kusumbe, PhD, Yookyung Jung, PhD, Guy Ledergor, MD, Idan Milo, PhD, Michael Gustave Poulos, PhD, Maria Garcia Fernandez, PhD, Alexander Kalinkovich, MDPhD, Aya Ludin, Orit Kollet, PhD, Guy Shakhar, PhD, Simon Mendez-Ferrer, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Ralf H. Adams, PhD, David T. Scadden, MD, Charles P. Lin, Tsvee Lapidot, PhD
Journal: Blood
Blood (2015) 126 (23): 664.
https://doi.org/10.1182/blood.V126.23.664.664
Published: 2015
Journal Articles

Production of BMP4 By Endothelial Cells Is Crucial for Endogenous Thymic Regeneration

Free
Tobias Wertheimer, Enrico Velardi, PhD, Christian Brede, PhD, Shiyun Xiao, Christopher C Kloss, PhD, Andreas Beilhack, MD, Nancy Manley, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Marcel van den Brink, MD PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2015) 126 (23): 637.
https://doi.org/10.1182/blood.V126.23.637.637
Published: 2015
Journal Articles

Notch Signaling By Either Notch1 or Notch2 Mediates Expansion of AGM-Derived Long-Term HSC Populations in Vitro

Free
Brandon K Hadland, MD PhD, Barbara Varnum-Finney, Randall T Moon, PhD, Michael Gustave Poulos, PhD, Jason M. Butler, PhD, Shahin Rafii, MD, Irwin D. Bernstein, MD
Journal: Blood
Blood (2014) 124 (21): 2897.
https://doi.org/10.1182/blood.V124.21.2897.2897
Published: 2014