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Juan José Lahuerta
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Journal Articles

Maintenance Therapy After Stem-Cell Transplantation for Multiple Myeloma with Bortezomib/Thalidomide Vs. Thalidomide Vs. alfa2b-Interferon: Final Results of a Phase III Pethema/GEM Randomized Trial

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Laura Rosiñnol, MD, Albert Oriol, Ana Isabel Teruel, Dolores Hernández, Javier Lopez-Jimenez, MD, Javier De La Rubia, MD, Miquel Granell, MD, Juan Besalduch, MD, PhD, Luis Palomera, MD, Yolanda González, MD, Maria Asunción Etxebeste, Joaquín Díaz-Mediavilla, Miguel Teodoro Hernández, Felipe de Arriba, Adrian Alegre, María Teresa Cibeira, Maria Victoria Mateos, MD, PhD, Joaquin Martinez, MD, Juan José Lahuerta, Jesús F San Miguel, Joan Bladé, MD
Journal: Blood
Blood (2012) 120 (21): 334.
https://doi.org/10.1182/blood.V120.21.334.334
Published: 2012
Journal Articles

Transcriptome Analysis Reveals Molecular Profiles Associated with Evolving Steps of Monoclonal Gammopathies.

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Lucía López Corral, Luis Antonio Corchete, Maria Victoria Mateos, MD, PhD, Ramon Garcia-Sanz, Encarna Fermiñán, Juan José Lahuerta, Joan Blade, MD, Albert Oriol, Ana Isabel Teruel, Maria Luz Martino, MD, Jose Hernández, Jesús M Hernández-Rivas, Jesus F San Miguel, Norma Gutierrez
Journal: Blood
Blood (2012) 120 (21): 2914.
https://doi.org/10.1182/blood.V120.21.2914.2914
Published: 2012
Journal Articles

Myelodysplasia-Associated Immunophenotypic Abnormalities of Bone Marrow (BM) Cells in Multiple Myeloma (MM): Are They Present At Diagnosis or Can Be Induced by Lenalidomide?

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Sergio Matarraz, Bruno Paiva, Maria Victoria Mateos, María Diez-Campelo, MD, PhD, Estefania Perez, María-Belén Vidriales, Lucía López-Corral, Pilar Giraldo, Miguel T. Hernandez, Felipe de Arriba, Javier De La Rubia, Joan Bargay, Fernando Leal da Costa, Graça Esteves, Juan José Lahuerta, Laura Rosiñol, MD, Joan Blade, Jesus F. San Miguel, MD, PhD, Alberto Orfao, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 5066.
https://doi.org/10.1182/blood.V118.21.5066.5066
Published: 2011
Journal Articles

Myeloablative Conditioning with Intravenous Busulfan In One Daily Dose and Fludarabine (BUF) for HLA-Identical Sibling Allogeneic HSCT In Myeloid Malignancies

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Javier De la Serna, MD, PhD, Jaime Sanz, MD, Arancha Bermudez, Carlos Vallejo, MD, PhD, David Serrano, Dolores Caballero, MD, Rafael De La Camara, MD, José M. Moraleda, Sonia Gonzalez, Ana García-Noblejas, MD, M. Cabrero, Juan José Lahuerta, Arturo Iriondo, Luis Benlloch, Guillermo Sanz, MD
Journal: Blood
Blood (2011) 118 (21): 3010.
https://doi.org/10.1182/blood.V118.21.3010.3010
Published: 2011
Journal Articles

High-Risk Cytogenetics and Persistent Minimal Residual Disease (MRD) by Multiparameter Flow Cytometry (MFC) Predict Unsustained Complete Response (CR) After Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma (MM)

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Bruno Paiva, Norma C. Gutierrez, Laura Rosiñol, MD, María-Belén Vidriales, María-Angeles Montalbán, Joaquín Martínez-López, MD, Maria Victoria Mateos, María Teresa Cibeira, Lourdes Courdón, Albert Oriol, María José Terol, MD, PhD, Maria-Asuncion Echebeste, Raquel de Paz, Felipe de Arriba, Luis Palomera, Javier De La Rubia, Joaquín Díaz-Mediavilla, Anna Sureda, MD, PhD, Ana Gorosquieta, Adrian Alegre, Alejandro Martín, Miguel T. Hernandez, Juan José Lahuerta, Joan Blade, Jesus F. San Miguel, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 630.
https://doi.org/10.1182/blood.V118.21.630.630
Published: 2011
Journal Articles

Smoldering Multiple Myeloma (SMM) At High-Risk of Progression to Symptomatic Disease: A Phase III, Randomized, Multicenter Trial Based On Lenalidomide-Dexamethasone (Len-Dex) As Induction Therapy Followed by Maintenance Therapy with Len Alone Vs No Treatment

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María-Victoria Mateos, MD, PhD, Lucía López-Corral, Miguel Hernández, Pilar Giraldo, MD, PhD, Javier De La Rubia, Felipe de Arriba, Laura Rosiñol, MD, Juan José Lahuerta, Luis Palomera, Joan Bargay, Albert Oriol, Felipe Prosper, MD, Javier López, Eduardo Olavarría, MD, Maria Luz Martino, MD, Ana-Isabel Teruel, Jose Mariano Hernández, Graça Esteves, Jose Mario JS Mariz, MD, Fernando Leal-da-Costa, MD, Adrian Alegre, MD, Jose-Luis Guzman, Ana López de la Guía, Jose Baquero, Nuria Quintana, Jose Luis García, Jesðs F. San Miguel
Journal: Blood
Blood (2011) 118 (21): 991.
https://doi.org/10.1182/blood.V118.21.991.991
Published: 2011
Journal Articles

Biological and Clinical Significance of CD81 Expression by Clonal Plasma Cells in High-Risk Smoldering and Symptomatic Multiple Myeloma (MM) Patients,

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Bruno Paiva, Norma C. Gutierrez, Xi Chen, María-Belén Vidriales, María-Angeles Montalbán, Laura Rosiñol, MD, Albert Oriol, Joaquín Martínez-López, MD, Maria Victoria Mateos, Lucía López-Corral, Elena Díaz-Rodríguez, Jose J. Perez, Elena Fernandez-Redondo, Felipe de Arriba, Luis Palomera, Enrique Bengoechea, María José Terol, MD, PhD, Raquel de Paz, Alejandro Martín, Jose Hernández, Alberto Orfao, MD, PhD, Juan José Lahuerta, Joan Blade, Atanasio Pandiella, Jesus F. San Miguel, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3936.
https://doi.org/10.1182/blood.V118.21.3936.3936
Published: 2011
Journal Articles

Multiparameter Flow Cytometry (MFC) Evaluation of Plasma Cell (PC) DNA Ploidy Status and Proliferative Rate in 595 Multiple Myeloma (MM) Patients (pts) Included in the Spanish GEM2000 and GEM2005<65years Trials: Clinical Value and Biological Insights,

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Bruno Paiva, María-Belén Vidriales, María-Angeles Montalbán, Jose J. Perez, Norma C. Gutierrez, Laura Rosiñol, MD, Joaquín Martínez-López, MD, Maria Victoria Mateos, Lourdes Courdón, Albert Oriol, María José Terol, MD, PhD, Maria Asunción Etxebeste, Raquel de Paz, Felipe de Arriba, Luis Palomera, Javier De La Rubia, Joaquín Díaz-Mediavilla, Anna Sureda, MD, PhD, Ana Gorosquieta, Adrian Alegre, Alejandro Martín, Miguel T. Hernandez, Juan José Lahuerta, Joan Blade, Jesús F San Miguel, MD PhD
Journal: Blood
Blood (2011) 118 (21): 3938.
https://doi.org/10.1182/blood.V118.21.3938.3938
Published: 2011
Journal Articles

Influence of Lenalidomide Treatment on Immune Effector Cells From High-Risk Smoldering Multiple Myeloma (SMM) Patients,

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Bruno Paiva, Maria Victoria Mateos, Lucía López-Corral, María-Belén Vidriales, Miguel T. Hernandez, Joan Bargay, Felipe de Arriba, Javier De La Rubia, Ana-Isabel Teruel, Pilar Giraldo, Laura Rosiñol, MD, Felipe Prosper, MD, Albert Oriol, Jose Hernández, Graça Esteves, Fernando Leal da Costa, Juan José Lahuerta, Joan Blade, Jesus F. San Miguel, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3944.
https://doi.org/10.1182/blood.V118.21.3944.3944
Published: 2011
Journal Articles

Under Scope of the Current Redefinition Process of Optimal Response in Multiple Myeloma: Assesment of Molecular Response by Fluorescent PCR of Ig Genes Has Similar Applicability and Prognosis Impact to Immunophenotypic Response. (A GEM/PETHEMA study),

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Elena Fernandez Redondo, Joaquin Martinez-Lopez, Ramón García-Sanz, María-Angeles Montalbán, Pilar Martinez-Sanchez, Bruno Paiva, Maria-Victoria Mateos, MD, PhD, Laura Rosiñol, MD, Maria Luisa Martin, Rosa M. Ayala, MD, PhD, Rafael Martinez, MD, Javier Lopez, Adrian Alegre, Joan Besalduch, Joan Bargay, MT Hernandez, Maria Eugenia Sarasquete, P. sanchez-Godoy, Manuel Callis, MD, Manuela Fernandez, Joan Blade, Jesus F. San Miguel, MD, PhD, Juan José Lahuerta
Journal: Blood
Blood (2011) 118 (21): 3951.
https://doi.org/10.1182/blood.V118.21.3951.3951
Published: 2011
Journal Articles

A Phase III PETHEMA/GEM Randomized Trial of Postransplant (ASCT) Maintenance in Multiple Myeloma: Superiority of Bortezomib/Thalidomide Compared with Thalidomide and Alfa-2b Interferon,

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Laura Rosiñol, MD, María Teresa Cibeira, Maria Victoria Mateos, Joaquin Martinez, MD, Albert Oriol, Ana Isabel Teruel, Dolores Hernández, Javier López, MD, Javier de la Rubia, Miquel Granell, MD, Juan Besalduch, MD, PhD, Luis Palomera, Yolanda González, MD, Maria Asunción Etxebeste, MD, Joaquín Díaz-Mediavilla, Miguel T Hernández, MD, Felipe de Arriba, Adrian Alegre, Juan José Lahuerta, Jesus F San Miguel, MD PhD, Joan Blade
Journal: Blood
Blood (2011) 118 (21): 3962.
https://doi.org/10.1182/blood.V118.21.3962.3962
Published: 2011
Journal Articles

Influence of Genetic Polymorphisms in CYP1A2 , CYP2C19, CYP3A4 , GSTP1 , MDR1 and PSMB5 Genes in Toxicity and Response to Induction Therapy in Multiple Myeloma Patients Included in the Trial of the Spanish PETHEMA/GEM 05 for Newly Diagnosed MM Elderly Patients (Age 65 or More)

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Cristina Castilla-Llorente, Felipe de Arriba, Virginia Pérez-Andreu, Maria Victoria Mateos, Rocio González-Conejero, José Rivera Pozo, Albert Oriol, Joaquin Martínez-López, Ana Isabel Teruel, Raquel de Paz, José García-Laraña, Enrique Bengoechea, Alejandro Martín, Joaquín Díaz-Mediavilla, Luis Palomera, Yolanda Gonzalez, Jose Mariano Hernández, Anna Sureda, Jose Luis Bello, Joan Bargay, Francisco Javier Peñalver, Maria Luisa Martin Mateos, María Teresa Cibeira, Juan José Lahuerta, Joan Blade, Jesús F. San Miguel
Journal: Blood
Blood (2011) 118 (21): 1412.
https://doi.org/10.1182/blood.V118.21.1412.1412
Published: 2011
Journal Articles

Maintenance Therapy with Bortezomib Plus Thalidomide (VT) or Bortezomib Plus Prednisone (VP) In Elderly Myeloma Patients Included In the GEM2005MAS65 Spanish Randomized Trial

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María-Victoria Mateos, MD, PhD, Albert Oriol, Ana-Isabel Teruel, Enrique Bengoechea, Montse Pérez, Javier López, Joaquín Díaz-Mediavilla, Jose Mariano Hernández, Felipe de Arriba, Yolanda Gonzalez, Joan Bladé, MD, Juan José Lahuerta, Jesðs F. San Miguel
Journal: Blood
Blood (2011) 118 (21): 477.
https://doi.org/10.1182/blood.V118.21.477.477
Published: 2011
Journal Articles

A Phase III PETHEMA/GEM Study of Induction Therapy Prior Autologous Stem Cell Transplantation (ASCT) In Multiple Myeloma: Superiority of VTD (Bortezomib/Thalidomide/Dexamethasone) Over TD and VBMCP/VBAD Plus Bortezomib

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Laura Rosiñol, María Teresa Cibeira, MD, PhD, Maria Victoria Mateos, MD, Joaquin Martinez, Albert Oriol, Ana Isabel Teruel, Dolores Hernández, José García-Laraña, Javier De La Rubia, Anna Sureda, MD, PhD, Juan Besalduch, Luis Palomera, Yolanda Gonzalez, Maria Asunción Etxebeste, Joaquín Díaz-Mediavilla, Miguel T. Hernández, Felipe de Arriba, Adrian Alegre, Juan José Lahuerta, Jesus F San Miguel, Joan Blade
Journal: Blood
Blood (2010) 116 (21): 307.
https://doi.org/10.1182/blood.V116.21.307.307
Published: 2010
Journal Articles

Analysis of Immunophenotypic Response (IR) by Multiparameter Flow Cytometry In 516 Myeloma Patients Included In Three Consecutive Spanish Trials

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Bruno Paiva, María-Belén Vidriales, María-Angeles Montalbán, María-Victoria Mateos, Laura Rosiñol, Joaquin Martinez, María Teresa Cibeira, Lourdes Courdón, Albert Oriol, María José Terol, Maria-Asuncion Echebeste, Raquel de Paz, Felipe de Arriba, Luis Palomera, Javier De La Rubia, Joaquín Díaz-Mediavilla, Jose Garcia-Laraña, Anna Sureda, MD, PhD, Ana Gorosquieta, Adrian Alegre, Alejandro Martín, Miguel T. Hernandez, Yolanda Gonzalez, Joan Blade, Juan José Lahuerta, Jesús F. San Miguel
Journal: Blood
Blood (2010) 116 (21): 1910.
https://doi.org/10.1182/blood.V116.21.1910.1910
Published: 2010
Journal Articles

Long Term Significance of Response in Multiple Myeloma After Stem Cell Transplantation.

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Joaquin Martínez-López, Joan Blade, M. Carmen Gomez del Castillo, Maria Victoria Mateos, Adrian Alegre, MD, José Garcia-Laraña, Anna Sureda, Javier de la Rubia, Eulogio Conde, MD, Rafael Martínez, Felipe de Arriba, Jose Luis Gomez Zamudio, Juan Besalduch, Rafael Cabrera, M. Cruz Biguria, Jose Maria Moraleda, J.F San Miguel, Juan José Lahuerta, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1811.
https://doi.org/10.1182/blood.V114.22.1811.1811
Published: 2009
Journal Articles

Impact of FISH and Cytogenetics On Overall and Event Free Survival in Myeloma: An IMWG Analysis of 9,897 Patients.

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Herve Avet-Loiseau, Brian G M Durie, Jeff Haessler, MD, John Crowley, PhD, Antje Hoering, Ph.D., Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., Orhan Sezer, Chaim Shustik, MD, Roman Hajek, MD, Harmut Goldschmidt, Pieter Sonneveld, Philippe Moreau, MD, Michel Attal, MD, Antonio Palumbo, M.D., Mario Boccadoro, MD, Jae Hoon Lee, Jan Westin, MD, PhD, Ingemar Turesson, MD, PhD, Jesús F. San Miguel, Joan Blade, Juan José Lahuerta, MD, PhD, Santiago Pavlovsky, MD, PhD, Dorotea Beatriz Fantl, MD, S.Vincent Rajkumar, M.D., Rafael Fonseca, MD
Journal: Blood
Blood (2009) 114 (22): 743.
https://doi.org/10.1182/blood.V114.22.743.743
Published: 2009
Journal Articles

Multicenter, Randomized, Open-Label, Phase III Trial of Lenalidomide-Dexamethasone (Len/dex) Vs Therapeutic Abstention in Smoldering Multiple Myeloma at High Risk of Progression to Symptomatic MM: Results of the First Interim Analysis.

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Maria-Victoria Mateos, MD, PhD, Lucía López-Corral, Miguel T Hernández, Javier de la Rubia, Juan José Lahuerta, MD, PhD, Pilar Giraldo, MD, Joan Bargay, MD, Laura Rosiñol, Albert Oriol, MD, Jose García-Laraña, Luis Palomera, Felipe de Arriba, Felipe Prosper, MD, Mariluz Martino, MD, Ana-Isabel Teruel, José Hernández, Graça Esteves, Mario Mariz, Adrian Alegre, MD, J.L. Guzmán, Nuria Quintana, Jose-Luis Garcia, Jesús F. San-Miguel, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 614.
https://doi.org/10.1182/blood.V114.22.614.614
Published: 2009
Journal Articles

A Phase I/II, National, Multicenter, Open Label Study of Bortezomib (Velcade) and Fludarabine, Cytarabine and Idarubicin (Flag-Ida) (V-Flag-Ida) in Pts with Relapsed and/or Refractory Acute Myeloblastic Leukemia (AML).

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Maria-Victoria Mateos, Rafael Martínez, Salut Brunet, Maria-Belén Vidriales, Albert Oriol, MD, Juan José Lahuerta, MD, PhD, Mari Luz Amigo, Jordi Esteve, Javier de la Rubia, Luis Palomera, Javier Bueno, Jesus F San Miguel
Journal: Blood
Blood (2009) 114 (22): 4140.
https://doi.org/10.1182/blood.V114.22.4140.4140
Published: 2009
Journal Articles

Thalidomide / Dexamethasone (TD) Vs. Bortezomib (Velcade) â /Thalidomide / Dexamethasone (VTD) Vs. VBMCP/VBAD/Velcade â as Induction Regimens Prior Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma (MM): Results of a Phase III PETHEMA/GEM Trial.

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Laura Rosiñol, Ma Teresa Cibeira, Joaquin Martinez, Maria Victoria Mateos, Albert Oriol, Ma José Terol, Jose García-Laraña, Dolores Hernández, Javier de la Rubia, Anna Sureda, Juan Besalduch, Luis Palomera, Yolanda Gonzalez, Ma Asuncion Echebeste, Joaquin Díaz-Mediavilla, Felipe de Arriba, Adrian Alegre, Miguel T Hernández, Juan José Lahuerta, J.F F San Miguel, Joan Blade
Journal: Blood
Blood (2009) 114 (22): 130.
https://doi.org/10.1182/blood.V114.22.130.130
Published: 2009