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Jose Ignacio Martín-Subero
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Journal Articles

INCREASED LEF1 PROTEIN LEVELS AND ISOFORM SWITCHING DRIVE CELL PROLIFERATION IN CHRONIC LYMPHOCYTIC LEUKEMIA

Available to Purchase
Judith Mateos-Jaimez, Anna Vidal Crespo, Stella Charalampopoulou, Raul Fernandez Perez, Vicente Chapaprieta, Víctor Jiménez-Martínez, Liska Caviedes-Cárdenas, Martí Duran-Ferrer, Guadalupe Espadas, Eduard Sabido, Anne Largeot, Sophie A. Herbst, Sascha Dietrich, Miguel Bastos Boente, Miguel Alcoceba, Ferran Nadeu, Ingo Ringshausen, Jerome Paggetti, Etienne Moussay, Dolors Colomer, Elías Campo, Alba Maiques-Diaz, Jose Ignacio Martin-Subero
Journal: Blood
Blood blood.2025030129.
https://doi.org/10.1182/blood.2025030129
Published: 2025
Includes: Supplemental data
Journal Articles

CD70 Deregulation in Follicular Lymphoma at Diagnosis Is Associated with Relapse and Opens New Avenues for Dual CD19-CD70 CAR-T Therapy

Free
Ferran Araujo-Ayala, Maria Ros, Mireia Bachiller, Raluca Alexandru, Pablo Mozas, Salut Colell, Judith Mateos-Jaimez, Cristina López, María Villalba-Esparza, Ferran Nadeu, Andrea Rivero, Cèlia Dobaño-López, Juan Garcia Valero, Neus Serrat, Marta Gimenez-Alejandre, Ariadna Giró, Daniel J Hodson, Armando Lopez-Guillermo, Elias Campo, Dolors Colomer, Alba Maiques-Diaz, Jose Ignacio Martin-Subero, Silvia Bea, Laura Magnano, Sonia Guedan, Carlos Eduardo De Andrea, Patricia Perez Galan
Journal: Blood
Blood (2024) 144 (Supplement 1): 333.
https://doi.org/10.1182/blood-2024-199167
Published: 2024
Journal Articles

The SOX11 Interactome Reveals the SOX11:SMARCA4 Complex As a Driver of Oncogenic Transcriptional Programs in Mantle Cell Lymphoma

Free
Amna De Bolòs, Maria Carreras-Caballé, Marta Sureda-Gómez, Marta Leonor Rodríguez, Stella Charalampopoulou, Robert Albero, Alba Maiques-Diaz, Heribert Playà-Albinyana, Dolors Colomer, José Ignacio Martín-Subero, Elías Campo, David Reverter, Josep Villanueva, Virginia Amador
Journal: Blood
Blood (2024) 144 (Supplement 1): 1371.
https://doi.org/10.1182/blood-2024-200616
Published: 2024
Journal Articles

Patient-Derived Follicular Lymphoma Tumoroids: A Tool to Recapitulate Biological Features of Low and High-Grade Lymphoma

Free
Ruben Gimenez, Neus Serrat, Miquel Castellote-Borrell, Victor Jiménez-Martínez, Eduardo Pérez del Río, Mireia Bachiller, Ferran Araujo-Ayala, Raul F Pérez, Ares Martínez-Farran, Jose Ángel Robles, Armando Lopez-Guillermo, Elias Campo, Josep Villanueva, Sonia Guedan, Jose Ignacio Martin-Subero, Judith Guasch, Daniel J Hodson, Dolors Colomer, Patricia Pérez Galán
Journal: Blood
Blood (2024) 144 (Supplement 1): 1613.
https://doi.org/10.1182/blood-2024-198454
Published: 2024
Journal Articles

Mapping Disease Transitions from Premalignant, Asymptomatic to Advanced Myeloma through Integrative Epigenomic and Transcriptional Analyses

Free
Aleksandra Kurowska, Azari Bantan, Raghad Shuwaikan, Itziar Cenzano, Paula Aguirre-Ruiz, Estíbaliz Miranda, Leire Garate, Amaia Vilas-Zornoza, Patxi San-Martin, Marta Larrayoz, Nahia Gómez-Echarte, Beñat Ariceta, Daniel Soto Ortiz, Turki Sobahy, José Ignacio Martín-Subero, Vincenzo Lagani, Jesper Tegnér, Jose A. Martinez-Climent, Xabier Agirre, Mikel Hernáez Arrazola, Felipe Prosper, David Gomez-Cabrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 1889.
https://doi.org/10.1182/blood-2024-209833
Published: 2024
Journal Articles

KDM6A regulates immune response genes in multiple myeloma

Free
Daphné Dupéré-Richer, Alberto Riva, Benjamin G. Barwick, Sayantan Maji, Heidi Casellas Román, Jianping Li, Umasankar De, Amin Sobh, Gabrielle Quickstad, Crissandra Piper, Marta Kulis, Teresa Ezponda, José Ignacio Martín-Subero, Giovanni Tonon, Weizhou Zhang, Constantine S. Mitsiades, Lawrence H. Boise, Richard L. Bennett, Jonathan D. Licht
Journal: Blood
Blood (2024) 144 (14): 1508–1520.
https://doi.org/10.1182/blood.2024024518
Published: 2024
Includes: Supplemental data
Journal Articles

Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation

Free
Elina Alaterre, Sara Ovejero, Caroline Bret, Laure Dutrieux, Dassou Sika, Raul Fernandez Perez, Marion Espéli, Thierry Fest, Michel Cogné, José Ignacio Martin-Subero, Pierre Milpied, Giacomo Cavalli, Jérôme Moreaux
Journal: Blood
Blood (2024) 144 (5): 496–509.
https://doi.org/10.1182/blood.2023023237
Published: 2024
Includes: Supplemental data
Journal Articles

SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma

Free
Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J. Johansson, Janne Lehtiö, Beatriz Garcia-Torre, Jose Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F. Schinazi, Baek Kim, Agnes L. Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z. Rassidakis, Ian A. Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
Journal: Blood
Blood (2024) 143 (19): 1953–1964.
https://doi.org/10.1182/blood.2023022241
Published: 2024
Includes: Supplemental data
Journal Articles

Light Chain Amyloidosis Plasma Cells Show Specific Chromatin Accessibility and Transcriptome

Free
Beñat Ariceta, Alice Nevone, Itziar Cenzano, Ane Amundarain, Amaia Vilas-Zornoza, Leire Garate, Paula Aguirre-Ruiz, Estibaliz Miranda, Patxi San-Martin, Paolo Milani, Ramon Lecumberri Villamediana, Diego Alignani, Giovanni Palladini, Bruno Paiva, Jose Ignacio Martin-Subero, Giampaolo Merlini, Jesus San-Miguel, Mikel Hernaez, David Gomez-Cabrero, Xabier Agirre, Mario Nuvolone, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 4676.
https://doi.org/10.1182/blood-2023-185614
Published: 2023
Journal Articles

Chromatin activation profiling of stereotyped chronic lymphocytic leukemias reveals a subset 8–specific signature

Free
Brief Report
Maria Tsagiopoulou, Vicente Chapaprieta, Nuria Russiñol, Beatriz García-Torre, Nikolaos Pechlivanis, Ferran Nadeu, Nikos Papakonstantinou, Niki Stavroyianni, Anastasia Chatzidimitriou, Fotis Psomopoulos, Elías Campo, Kostas Stamatopoulos, José Ignacio Martín-Subero
Journal: Blood
Blood (2023) 141 (24): 2955–2960.
https://doi.org/10.1182/blood.2022016587
Published: 2023
Includes: Supplemental data
Journal Articles

The IGLV3-21 R110 Defines a Subset of Chronic Lymphocytic Leukemia with Intermediate Epigenetic Subtype and Poor Outcome

Free
Ferran Nadeu, Romina Royo, Guillem Clot, Martí Duran-Ferrer, Alba Navarro, PhD, Silvia Martín, Junyan Lu, Thorsten Zenz, Tycho Baumann, Pedro Jares, Xose S Puente, PhD, Jose Ignacio Martin-Subero, Julio Delgado, MD PhD, Elias Campo, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–44.
https://doi.org/10.1182/blood-2020-134786
Published: 2020
Journal Articles

Whole-Genome Epigenomic Analysis in Multiple Myeloma Reveals DNA Hypermethylation of B-Cell Specific Enhancers

Free
Xabier Agirre, PhD, Giancarlo Castellano, Marien Pascual, Simon Health, Marta Kulis, Victor Segura, PhD, Anke Bergmann, Anna Esteve, Angelika Merkel, Emanuele Raineri, Lidia Agueda, Julie Blanc, David Richardson, Laura Clarke, Nuria Russiñol, Ana C. Queirós, Renée Beekman, Juan R. Rodriguez-Madoz, Edurne San José-Enériz, PhD, Fang Fang, Norma Carmen Gutierrez, PhD MD, José M García-Verdugo, Michael I. Robson, Eric C. Schirmer, Elisabeth Guruceaga, Joost H.A. Martens, Marta Gut, María José Calasanz, PhD, Paul Flicek, Reiner Siebert, Elias Campo, MD PhD, Jesus F. San Miguel, Ari M Melnick, MD, Hendrik G. Stunnenberg, Ivo G. Gut, Felipe Prosper, MD, Jose Ignacio Martín-Subero
Journal: Blood
Blood (2014) 124 (21): 2032.
https://doi.org/10.1182/blood.V124.21.2032.2032
Published: 2014
Journal Articles

SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

Free
Maria Carmela Vegliante, Jara Palomero, Patricia Pérez-Galán, Gaël Roué, Giancarlo Castellano, Alba Navarro, Guillem Clot, Alexandra Moros, Helena Suárez-Cisneros, Sílvia Beà, Luis Hernández, Anna Enjuanes, Pedro Jares, Neus Villamor, Dolors Colomer, José Ignacio Martín-Subero, Elias Campo, Virginia Amador
Journal: Blood
Blood (2013) 121 (12): 2175–2185.
https://doi.org/10.1182/blood-2012-06-438937
Published: 2013
Includes: Supplemental data
Journal Articles

Epigenomic Analysis of Acute Myeloid Leukemia Identifies Specific Patterns and Markes with Clinical and Biological Relevance.

Free
Sara Alvarez, MD, PhD, Javier Suela, PhD, Ana Valencia, MD, Agustin Fernandez, PhD, Mark Wunderlich, MS, Xabier Agirre, PhD, Felipe Prosper, MD, Jose Ignacio Martin-Subero, PhD, Alba Maiques, MSc, Francesco Acquadro, MSc, Sandra Rodriguez-Perales, PhD, Maria J. Calasanz, PhD, Jose Roman-Gomez, MD, Reiner Siebert, MD, PhD, James C. Mulloy, PhD, José Cervera, MD, PhD, Miguel A. Sanz, MD, PhD, Manel Esteller, MD, PhD, Juan C Cigudosa, PhD
Journal: Blood
Blood (2009) 114 (22): 2394.
https://doi.org/10.1182/blood.V114.22.2394.2394
Published: 2009
Journal Articles

Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)

Free
Takashi Akasaka, Theodore Balasas, Lisa J. Russell, Kei-ji Sugimoto, Aneela Majid, Renata Walewska, E. Loraine Karran, David G. Brown, Kelvin Cain, Lana Harder, Stefan Gesk, Jose Ignacio Martin-Subero, Mark G. Atherton, Monika Brüggemann, María José Calasanz, Teresa Davies, Oskar A. Haas, Anne Hagemeijer, Helena Kempski, Michel Lessard, Debra M. Lillington, Sarah Moore, Florence Nguyen-Khac, Isabelle Radford-Weiss, Claudia Schoch, Stéphanie Struski, Polly Talley, Melanie J. Welham, Helen Worley, Jon C. Strefford, Christine J. Harrison, Reiner Siebert, Martin J. S. Dyer
Journal: Blood
Blood (2006) 109 (8): 3451–3461.
https://doi.org/10.1182/blood-2006-08-041012
Published: 2006
Includes: Supplemental data
Journal Articles

Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma

Free
Clinical Trials & Observations
Hongtao Ye, Hongxiang Liu, Ayoma Attygalle, Andrew C. Wotherspoon, Andrew G. Nicholson, Frédéric Charlotte, Veronique Leblond, Paul Speight, John Goodlad, Anne Lavergne-Slove, Jose Ignacio Martin-Subero, Reiner Siebert, Ahmet Dogan, Peter G. Isaacson, Ming-Qing Du
Journal: Blood
Blood (2003) 102 (3): 1012–1018.
https://doi.org/10.1182/blood-2002-11-3502
Published: 2003