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Journal Articles

Developing Novel Targeted Therapies Using the High-Risk Vq Myeloma Model

Evan Flietner, BS, Zhi Wen, PhD, Adhithi Rajagopalan, BS, Joshua Wiesner, BS, Xiaona You, PhD, Yun Zhou, MS, Terra Lasho, PhD, Mrinal M. Patnaik, MDMBBS, Demin Wang, PhD, Robert Burns, MD, Natalie S. Callander, MD, Fotis Asimakopoulos, PhDMBBChir,, Jing Zhang, PhD

Blood (2020) 136 (Supplement 1): 10–11.

https://doi.org/10.1182/blood-2020-137148

Published: 2020

Journal Articles

Increased Adhesiveness of Red Blood Cells from Sickle Cell Trait Carriers after Exposure to Daunirubicin Breast Cancer Chemotherapeutic Agent

Jing Zhang, PhD, Matthew Hadfield, DO, Helen Swede, PhD, Biree Andemariam, MD, George Lykotrafitis, PhD

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-143324

Published: 2020

Journal Articles

YY1 Promotes SCF/c-Kit Signaling and HSC Self-Renewal in Fetal Hematopoiesis

Deependra Kumar Singh, PhD, Zhanping Lu, PhD, Shuai Jia, PhD, Xiaona You, PhD, Jing Zhang, PhD, Xuan Pan, PhD DVM

Blood (2020) 136 (Supplement 1): 27.

https://doi.org/10.1182/blood-2020-137254

Published: 2020

Journal Articles

Repurposing Nelarabine to Induce Differentiation of Acute Myeloid Leukemia

Hanying Wang, Xin He, MD, Feiteng Huang, MS, Haojie Dong, PhD, Wei Chen, PhD, Zheng Li, MS, Jie Sun, PhD, Yinghui Zhu, PhD, Lei Zhang, MD, Yuhui Wu, MD, Lifeng Feng, PhD, Jing Zhang, PhD, Samer Khaled, MD, Guido Marcucci, MD, David Sykes, MD PhD, Hongchuan Jin, MD PhD, Xian Wang, MD PhD, Ling Li, PhD

Blood (2020) 136 (Supplement 1): 26.

https://doi.org/10.1182/blood-2020-139922

Published: 2020

Journal Articles

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Athanasios Papadas, MD, Evan Flietner, BS, Zachary Morrow, BS, Joshua Wiesner, Alexander Cicala, Adam Pagenkopf, BS, Chelsea L. Hope, PhD, Adhithi Rajagopalan, BS, Zhi Wen, PhD, Philip Emmerich, Dustin Deming, Shigeki Miyamoto, PhD, Peiman Hematti, MD, Natalie Scott Callander, MD, Alexander Rakhmilevich, Mario Otto, MD PhD, Christian M. Capitini, MD, Jing Zhang, PhD, Fotis Asimakopoulos, PhDMBBChir,

Blood (2019) 134 (Supplement_1): 1210.

https://doi.org/10.1182/blood-2019-131582

Published: 2019

Journal Articles

Loss of Asxl1 Cooperates with Oncogenic Nras to Drive CMML Progression

Xiaona You, PhD, Zhi Wen, PhD, Guangyao Kong, Adhithi Rajagopalan, BS, Erik A. Ranheim, MD PhD, Yun Zhou, MS, Mrinal M Patnaik, MDMBBS, Jing Zhang, PhD

Blood (2019) 134 (Supplement_1): 3790.

https://doi.org/10.1182/blood-2019-131347

Published: 2019

Journal Articles

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Joydeep Ghosh, PhD, Jing Zhang, PhD, Chi Zhang, PhD, Xinxin Huang, PhD, Safa F. Mohamad, MS, Maegan L. Capitano, PhD, Andrea M. Gunawan, Scott Cooper, MS, Bin Guo, PhD, Qingchun Cai, PhD, Hal E. Broxmeyer, PhD, Edward F. Srour, PhD

Blood (2018) 132 (Supplement 1): 1282.

https://doi.org/10.1182/blood-2018-99-119251

Published: 2018

Journal Articles

Reconstructing the Clonal and Mutational Architecture of Myeloma through Avian Leukosis Virus (ALV)-Mediated Genome Editing

Zachary Morrow, BS, Alexander Cicala, Evan Flietner, BS, Athanasios Papadas, MD, Adam Pagenkopf, BS, Zhi Wen, PhD, Adhithi Rajagopalan, BS, Poulikos Poulikakos, PhD, Natalie Scott Callander, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD, Jing Zhang, PhD, Fotios Asimakopoulos, PhD MBBChir,

Blood (2018) 132 (Supplement 1): 4480.

https://doi.org/10.1182/blood-2018-99-115288

Published: 2018

Journal Articles

Single-Nucleotide Human Disease Mutation Inactivates a Blood-Regenerative Enhancer

Alexandra Soukup, BS, PhD, Charu Mehta, MS, Peng Liu, PhD, Miao Cao, Inga Hofmann, MD, Yun Zhou, MS, Jing Zhang, PhD, Kyunghee Choi, PhD, Kirby D Johnson, PhD, Emery H Bresnick, PhD

Blood (2018) 132 (Supplement 1): 2564.

https://doi.org/10.1182/blood-2018-99-113008

Published: 2018

Journal Articles

Mice Expressing MYC and Nras Q61R in Germinal Center B Cells Develop Highly Aggressive Multiple Myeloma

Adhithi Rajagopalan, BS, Zhi Wen, PhD, Quinlan Furumo, Erik A. Ranheim, MD PhD, Remington Finn, Evan Flietner, BS, Grant Yun, Yun Zhou, MS, Mei Yu, PhD, Natalie Scott Callander, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD, Robert Burns, PhD, Demin Wang, PhD, Fotios Asimakopoulos, PhDMBBChir,, Jing Zhang, PhD

Blood (2018) 132 (Supplement 1): 1006.

https://doi.org/10.1182/blood-2018-99-116757

Published: 2018

Journal Articles

Canonical Notch Signaling Is Required for Kras G12D -Induced Myeloproliferative Neoplasm

Xiaona You, PhD, Guangyao Kong, Zhi Wen, Yuan-I Chang, Erik A. Ranheim, MD PhD, Eric Padron, MD, Jing Zhang, PhD

Blood (2017) 130 (Supplement 1): 1220.

https://doi.org/10.1182/blood.V130.Suppl_1.1220.1220

Published: 2017

Journal Articles

Molecular Determinants for Polycomb Group Protein YY1 Control of Hematopoietic Stem Cell Quiescence

Zhanping Lu, PhD, Courtney Hong, Guangyao Kong, PhD, Anna L F. V. Assumpção, Irene Ong, Emery H Bresnick, PhD, Jing Zhang, PhD, Xuan Pan, PhD DVM

Blood (2017) 130 (Supplement 1): 1140.

https://doi.org/10.1182/blood.V130.Suppl_1.1140.1140

Published: 2017

Journal Articles

Mitigating Detrimental Influences of Ambient Air Collection of Bone Marrow By Hypoxic Collection Results in Detection of Functionally Enhanced Aged Mouse Hematopoiesis: Reflecting Stem Cell Expression Levels of CXCR4, CCR5 and ROS

Maegan Capitano, PhD, Scott Cooper, MS, Bin Guo, PhD, Jing Zhang, PhD, Xinxin Huang, PhD, Qingchun Cai, PhD, Heather A. O'Leary, PhD, Hui Lin Chua, PhD, Artur Plett, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD

Blood (2017) 130 (Supplement 1): 2420.

https://doi.org/10.1182/blood.V130.Suppl_1.2420.2420

Published: 2017

Journal Articles

Dnmt3a Haploisufficiency Cooperates with Oncogenic Kras to Promote an Early-Onset T-Cell Leukemia

Yuan-I Chang, PhD, Guangyao Kong, PhD, Jing Zhang, PhD, Erik A. Ranheim, MD

Blood (2016) 128 (22): 2729.

https://doi.org/10.1182/blood.V128.22.2729.2729

Published: 2016

Journal Articles

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

Guangyao Kong, PhD, Yuan-I Chang, PhD, Jingfang Zhang, PhD, Erik A. Ranheim, MD, Xinmin Zhang, Yun Zhou, Yangang Liu, Lan Zhou, MD PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD

Blood (2016) 128 (22): 1565.

https://doi.org/10.1182/blood.V128.22.1565.1565

Published: 2016

Journal Articles

Kras Is Critical for CD8 T Cell Antiviral Function

Yuhong Chen, PhD, Yongwei Zheng, PhD, Xiaona You, PhD, Gang Xin, PhD, Mei Yu, PhD, Guoping Fu, PhD, Fen Zhou, Wen Zhu, Weiguo Cui, PhD, Jing Zhang, PhD, Renren Wen, PhD, Demin Wang, PhD

Blood (2015) 126 (23): 284.

https://doi.org/10.1182/blood.V126.23.284.284

Published: 2015

Journal Articles

Wild-Type Kras Inhibits Nras Q61R/+ -Induced Leukemias

Zhi Wen, PhD MD, Jing Zhang, PhD

Blood (2015) 126 (23): 1249.

https://doi.org/10.1182/blood.V126.23.1249.1249

Published: 2015

Journal Articles

Kras Is Critical for B Cell Lymphopoiesis

Yongwei Zheng, PhD, Yuhong Chen, PhD, Xiaona You, PhD, Mei Yu, PhD, Guoping Fu, PhD, Xinlin Su, Wen Zhu, Zhihong Wu, Jing Zhang, PhD, Renren Wen, PhD, Demin Wang, PhD

Blood (2015) 126 (23): 3588.

https://doi.org/10.1182/blood.V126.23.3588.3588

Published: 2015

Journal Articles

Loss of IKKβ Increases the Number and Self-Renewal Capacity of Hematopoietic Stem Cells

Jing Zhang, PhD, Li Li, PhD, Albert S. Baldwin, PhD, Alan D. Friedman, MD, Ido Paz-Priel, MD

Blood (2014) 124 (21): 4345.

https://doi.org/10.1182/blood.V124.21.4345.4345

Published: 2014

Journal Articles

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

Guangyao Kong, PhD, Yuan-I Chang, PhD, Erik A. Ranheim, MD, Yun Zhou, Yangang Liu, Paul Lambert, PhD, Lan Zhou, MD PhD, Pamela Stanley, PhD, Warren S. Pear, MD PhD, Jing Zhang, PhD

Blood (2014) 124 (21): 261.

https://doi.org/10.1182/blood.V124.21.261.261

Published: 2014

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Developing Novel Targeted Therapies Using the High-Risk Vq Myeloma Model

Increased Adhesiveness of Red Blood Cells from Sickle Cell Trait Carriers after Exposure to Daunirubicin Breast Cancer Chemotherapeutic Agent

YY1 Promotes SCF/c-Kit Signaling and HSC Self-Renewal in Fetal Hematopoiesis

Repurposing Nelarabine to Induce Differentiation of Acute Myeloid Leukemia

Versican Proteolytic Fragments (Matrikines) Regulate the Intratumoral Dendritic Cell Milieu In Vivo: Implications for in Situ Tumor Vaccination

Loss of Asxl1 Cooperates with Oncogenic Nras to Drive CMML Progression

CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways

Reconstructing the Clonal and Mutational Architecture of Myeloma through Avian Leukosis Virus (ALV)-Mediated Genome Editing

Single-Nucleotide Human Disease Mutation Inactivates a Blood-Regenerative Enhancer

Mice Expressing MYC and Nras Q61R in Germinal Center B Cells Develop Highly Aggressive Multiple Myeloma

Canonical Notch Signaling Is Required for Kras G12D -Induced Myeloproliferative Neoplasm

Molecular Determinants for Polycomb Group Protein YY1 Control of Hematopoietic Stem Cell Quiescence

Mitigating Detrimental Influences of Ambient Air Collection of Bone Marrow By Hypoxic Collection Results in Detection of Functionally Enhanced Aged Mouse Hematopoiesis: Reflecting Stem Cell Expression Levels of CXCR4, CCR5 and ROS

Dnmt3a Haploisufficiency Cooperates with Oncogenic Kras to Promote an Early-Onset T-Cell Leukemia

Downregulating Notch Counteracts Kras G12D -Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm

Kras Is Critical for CD8 T Cell Antiviral Function

Wild-Type Kras Inhibits Nras Q61R/+ -Induced Leukemias

Kras Is Critical for B Cell Lymphopoiesis

Loss of IKKβ Increases the Number and Self-Renewal Capacity of Hematopoietic Stem Cells

Downregulating Notch Signaling in Kras G12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner

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American Society of Hematology

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