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Journal Articles

Valine as a Key Metabolic Regulator of Hematopoietic Stem Cell Maintenance

Hiromitsu Nakauchi, MD PhD

Blood (2017) 130 (Supplement 1): SCI-20.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-20.SCI-20

Published: 2017

Journal Articles

Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells

Tomohiro Ishigaki, MD PhD, Yuki Taya, MD PhD, Satoshi Yamazaki, PhD, Seiichiro Kobayashi, MD PhD, Nobuhiro Ohno, MD, Kaoru Uchimaru, MD PhD, Arinobu Tojo, MD PhD, Hiromitsu Nakauchi, MD PhD

Blood (2016) 128 (22): 1765.

https://doi.org/10.1182/blood.V128.22.1765.1765

Published: 2016

Journal Articles

In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells from Induced Pluripotent Stem Cells through Hemogenic Endothelium

Masao Tsukada, MD, Satoshi Yamazaki, PhD, Yasunori Ota, MD PhD, Hiromitsu Nakauchi, MD PhD

Blood (2016) 128 (22): 3866.

https://doi.org/10.1182/blood.V128.22.3866.3866

Published: 2016

Journal Articles

Protection of Transplanted Hematopoietic Stem Cells from Inflammatory Recipient Marrow Environment through Specific TNF-α Signal Blockade

Takashi Ishida, MD, Sachie Suzuki, MD, Chen-Yi Lai, PhD, Masaaki Higashihara, MD, PhD, Hiromitsu Nakauchi, MD PhD, Makoto Otsu, MD, PhD

Blood (2015) 126 (23): 1867.

https://doi.org/10.1182/blood.V126.23.1867.1867

Published: 2015

Journal Articles

Proof of Benefit in Multiple-Cord Blood Transplantation Evidenced By Early Hematopoietic Reconstitution

Takashi Ishida, MD, Satoshi Takahashi, MD,PhD, Chen-Yi Lai, PhD, Masaaki Higashihara, MD, PhD, Hiromitsu Nakauchi, MD PhD, Makoto Otsu, MD, PhD

Blood (2015) 126 (23): 3071.

https://doi.org/10.1182/blood.V126.23.3071.3071

Published: 2015

Journal Articles

Srsf2 P95H Mutation Causes Impaired Stem Cell Repopulation and Hematopoietic Differentiation in Mice

Ayana Kon, MD PhD, Satoshi Yamazaki, PhD, Yasunori Ota, MD PhD, Keisuke Kataoka, MD PhD, Yusuke Shiozawa, MD, Maiko Morita, MS, Tetsuichi Yoshizato, MD, Masashi Sanada, MD PhD, Kenichi Yoshida, MD PhD, Manabu Nakayama, PhD, Haruhiko Koseki, PhD, Hiromitsu Nakauchi, MD PhD, Seishi Ogawa, MD PhD

Blood (2015) 126 (23): 1649.

https://doi.org/10.1182/blood.V126.23.1649.1649

Published: 2015

Journal Articles

Comprehensive Analysis of Surface Antigens on Adult T-Cell Leukemia/Lymphoma (ATL) Cells and Search for ATL-Initiating Cell Markers

Tomohiro Ishigaki, MD, Seiichiro Kobayashi, MD PhD, Nobuhiro Ohno, MD PhD, Nobuaki Nakano, MD, Atae Utsunomiya, MD PhD, Satoshi Yamazaki, PhD, Nobukazu Watanabe, MD PhD, Kaoru Uchimaru, MD PhD, Arinobu Tojo, MD PhD, Hiromitsu Nakauchi, MD PhD

Blood (2014) 124 (21): 1674.

https://doi.org/10.1182/blood.V124.21.1674.1674

Published: 2014

Journal Articles

A Novel Chemical Approach to Expand Platelets Using Immortalized Megakaryocyte Progenitor Cells Derived from Human Induced Pluripotent Stem Cells

Ayako Otani, Tomo Koike, Natsuki Abe, Takanori Nakamura, PhD, Taito Nishino, PhD, Hiromitsu Nakauchi, MD PhD, Koji Eto, MD, PhD

Blood (2014) 124 (21): 3845.

https://doi.org/10.1182/blood.V124.21.3845.3845

Published: 2014

Journal Articles

A New Strategy to Overcome the Cell Dose Barrier to Umbilical Cord Blood Transplants: A Proof of Early Hematopoietic Reconstitution By Combined Multiple Units of Allogeneic Stem/Progenitor Cells

Takashi Ishida, MD, Makoto Otsu, MD PhD, Satoshi Takahashi, MD PhD, Masaaki Higashihara, MD PhD, Hiromitsu Nakauchi, MD PhD

Blood (2014) 124 (21): 3810.

https://doi.org/10.1182/blood.V124.21.3810.3810

Published: 2014

Journal Articles

Epidermal Growth Factor-like Domain 7 Promotes Hematopoietic Stem Cell Expansion and Increases Myeloid-Megakaryocytic Lineage Priming through beta3 Integrin

Chiemi Nishida, PhD, Yousef Salama, Ismael Gritli, PhD, Terumasa Umemoto, PhD, Hiromitsu Nakauchi, MD PhD, Koichi Hattori, MD PhD, Heissig Beate, MD PhD

Blood (2014) 124 (21): 2919.

https://doi.org/10.1182/blood.V124.21.2919.2919

Published: 2014

Journal Articles

Role Of Sf3b1 On Hematopoiesis

Manabu Matsunawa, MD, Ryo Yamamoto, MD, PhD, Masashi Sanada, MD, Aiko Sato, PhD, Yusuke Shiozawa, MD, Kenichi Yoshida, MD, Yasunobu Nagata, MD, Ayana Kon, MD, Tetsuichi Yoshizato, MD, Makoto Otsu, MD, PhD, Kyoichi Isono, Haruhiko Koseki, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Seishi Ogawa, MD, PhD

Blood (2013) 122 (21): 600.

https://doi.org/10.1182/blood.V122.21.600.600

Published: 2013

Journal Articles

Novel Therapeutic Approach To Graft-Versus-Host Disease With Allele-Specific Anti-HLA Monoclonal Antibody

Yusuke Nakauchi, MD, Satoshi Yamazaki, PhD, Stephanie Carlisle Napier, Jo-ichi Usui, MD, PhD, Yasunori Ota, MD, PhD, Satoshi Takahashi, MD, PhD, Nobukazu Watanabe, MD, PhD, Hiromitsu Nakauchi, MD, PhD

Blood (2013) 122 (21): 4462.

https://doi.org/10.1182/blood.V122.21.4462.4462

Published: 2013

Journal Articles

Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML

Masatoshi Sakurai, MD, Hiroyoshi Kunimoto, MD, Naohide Watanabe, MD, PhD, Yumi Fukuchi, PhD, Ken Sadahira, MD, Shinsuke Yuasa, MD, PhD, Keiichi Fukuda, MD, PhD, Satoshi Yamazaki, PhD, Hiromitsu Nakauchi, MD, PhD, Yasuhiro Ebihara, MD, PhD, Kohichiro Tsuji, MD, PhD, Etsuro Ito, Yuka Harada, MD, PhD, Hironori Harada, MD, PhD, Shinichiro Okamoto, MD, PhD, Hideaki Nakajima, MD, PhD

Blood (2012) 120 (21): 767.

https://doi.org/10.1182/blood.V120.21.767.767

Published: 2012

Journal Articles

Recurrent Mutations of Multiple Components of Cohesin Complex in Myeloid Neoplasms

Ayana Kon, MD, Lee-Yung Shih, MD, Masashi Minamino, MA, Masashi Sanada, MD, Yuichi Shiraishi, PhD, Yasunobu Nagata, MD, Kenichi Yoshida, MD, Yusuke Okuno, MD, Masashige Bando, PhD, Shumpei Ishikawa, MD, PhD, Aiko Sato-Otsubo, PhD, Genta Nagae, MD, PhD, Claudia Haferlach, MD, Daniel Nowak, MD, Yusuke Sato, MD, Tamara Alpermann, Masao Nagasaki, PhD, Teppei Shimamura, MD, PhD, Hiroko Tanaka, BA, Kenichi Chiba, BA, Ryo Yamamoto, MD, PhD, Tomoyuki Yamaguchi, PhD, Makoto Otsu, MD, PhD, Naoshi Obara, MD, PhD, Mamiko Sakata-Yanagimoto, MD, PhD, Tsuyoshi Nakamaki, MD, Ken Ishiyama, MD, PhD, Florian Nolte, MD, Wolf-Karsten Hofmann, Shuichi Miyawaki, MD, Shigeru Chiba, MD, PhD, Hiraku Mori, MD, PhD, Hiromitsu Nakauchi, MD, PhD, H. Phillip Koeffler, MD, PhD, Hiroyuki Aburatani, MD, PhD, Torsten Haferlach, MD, Katsuhiko Shirahige, PhD, Satoru Miyano, PhD, Seishi Ogawa, MD, PhD

Blood (2012) 120 (21): 782.

https://doi.org/10.1182/blood.V120.21.782.782

Published: 2012

Journal Articles

Biological Analysis of SRSF2 Mutations in Leukemogenesis

Manabu Matsunawa, MD, Masashi Sanada, MD, Ryo Yamamoto, MD, PhD, Kenichi Yoshida, MD, Yasunobu Nagata, MD, Ayana Kon, MD, Tetsuichi Yoshizato, MD, Makoto Otsu, MD, PhD, Hiromitsu Nakauchi, MD, PhD, Seishi Ogawa, MD, PhD

Blood (2012) 120 (21): 1282.

https://doi.org/10.1182/blood.V120.21.1282.1282

Published: 2012

Journal Articles

MT1-MMP Plays a Critical Role in Hematopoiesis by Regulating HIF-Mediated Chemo-/Cytokine Gene Transcription within Niche Cells.

Chiemi Nishida, ph.D., Kaori Sato-Kusubata, ph.D., Yoshihiko Tashiro, ph.D., M.D., Ismael Gritli, Aki Sato, M.D., Makiko Ohki-Koizumi, M.D., ph.D., Yohei Morita, ph.D., Makoto Nagano, ph.D., Takeharu Sakamoto, ph.D., Naohiko Koshikawa, ph.D., Takahiro Kuchimaru, ph.D., Shinae Kizaka-Kondo, ph.D., Motoharu Seiki, ph.D., Hiromitsu Nakauchi, MD, PhD, Heissig Beate, ph.D., M.D., Koichi Hattori, MD, PhD

Blood (2012) 120 (21): 2351.

https://doi.org/10.1182/blood.V120.21.2351.2351

Published: 2012

Journal Articles

In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements

Toshinobu Nishimura, Shin Kaneko, M.D., Ph.D., Yoko Tajima, Naoya Takayama, M.D., Ph.D., Ai Tachikawa-Kawana, Ph.D., Koji Eto, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD

Blood (2011) 118 (21): 2984.

https://doi.org/10.1182/blood.V118.21.2984.2984

Published: 2011

Journal Articles

Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells

Sou Nakamura, Naoya Takayama, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD, Koji Eto, M.D., Ph.D.

Blood (2011) 118 (21): MRG-1.

https://doi.org/10.1182/blood.V118.21.MRG-1.MRG-1

Published: 2011

Journal Articles

Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation

Takafumi Hiramoto, Yasuhiro Ebihara, MD, PhD, Yoko Mizoguchi, MD, Kazuhiro Nakamura, MD, PhD, Shinji Mochizuki, MD, PhD, Shohei Yamamoto, MD, PhD, Emiko Matsuzaka, PhD, Sachiyo Hanada, Ryoko Ohnishi, Kenzaburo Tani, PhD, M.D., Koji Eto, M.D., Ph.D., Hiromitsu Nakauchi, MD, PhD, Masao Kobayashi, MD, PhD, Kohichiro Tsuji, MD, PhD

Blood (2011) 118 (21): 730.

https://doi.org/10.1182/blood.V118.21.730.730

Published: 2011

Journal Articles

Nov/CCN3 Enhances Long-Term Repopulating Activity of Mouse Hematopoietic Stem Cells Via Intergin β3 Signaling Collaborating with Thrombopoietin

Jun Ishihara, Terumasa Umemoto, Ph.D, Masayuki Yamato, Ph.D, Yoshiko Shiratsuchi, Ph.D, Brian G. Petrich, PhD, Hiromitsu Nakauchi, MD, PhD, Koji Eto, M.D., Ph.D., Toshio Kitamura, MD, PhD, Teruo Okano, Ph.D

Blood (2011) 118 (21): 862.

https://doi.org/10.1182/blood.V118.21.862.862

Published: 2011

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Valine as a Key Metabolic Regulator of Hematopoietic Stem Cell Maintenance

Proof of Merit in New Diet Therapy Against Adult T-Cell Leukemia/Lymphoma: Applying Specific Amino Acid Dependency of Leukemia/Lymphoma Cells

In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells from Induced Pluripotent Stem Cells through Hemogenic Endothelium

Protection of Transplanted Hematopoietic Stem Cells from Inflammatory Recipient Marrow Environment through Specific TNF-α Signal Blockade

Proof of Benefit in Multiple-Cord Blood Transplantation Evidenced By Early Hematopoietic Reconstitution

Srsf2 P95H Mutation Causes Impaired Stem Cell Repopulation and Hematopoietic Differentiation in Mice

Comprehensive Analysis of Surface Antigens on Adult T-Cell Leukemia/Lymphoma (ATL) Cells and Search for ATL-Initiating Cell Markers

A Novel Chemical Approach to Expand Platelets Using Immortalized Megakaryocyte Progenitor Cells Derived from Human Induced Pluripotent Stem Cells

A New Strategy to Overcome the Cell Dose Barrier to Umbilical Cord Blood Transplants: A Proof of Early Hematopoietic Reconstitution By Combined Multiple Units of Allogeneic Stem/Progenitor Cells

Epidermal Growth Factor-like Domain 7 Promotes Hematopoietic Stem Cell Expansion and Increases Myeloid-Megakaryocytic Lineage Priming through beta3 Integrin

Role Of Sf3b1 On Hematopoiesis

Novel Therapeutic Approach To Graft-Versus-Host Disease With Allele-Specific Anti-HLA Monoclonal Antibody

Impaired Hematopoietic Differentiation of iPSCs Derived From Patients with FPD/AML

Recurrent Mutations of Multiple Components of Cohesin Complex in Myeloid Neoplasms

Biological Analysis of SRSF2 Mutations in Leukemogenesis

MT1-MMP Plays a Critical Role in Hematopoiesis by Regulating HIF-Mediated Chemo-/Cytokine Gene Transcription within Niche Cells.

In Vitro Generation of Mature T Lymphocytes From Human Ips Cells and Genetic Analysis of TCR Gene Rearrangements

Platelet Production System Using An Immortalized Megakaryocyte Cell Line Derived From Human Pluripotent Stem Cells

Suppressed Neutrophil Development in Hematopoiesis of Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with ELA2 Mutation

Nov/CCN3 Enhances Long-Term Repopulating Activity of Mouse Hematopoietic Stem Cells Via Intergin β3 Signaling Collaborating with Thrombopoietin

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