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Journal Articles

Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

Thiago Mantello Bianco, MSc, Diego Antonio Pereira-Martins, MSc, Patrícia Vianna Bonini Palma, BSc, Josiane Lilian Schiavinato, PhD, Cleide Araújo Silva, MSc, Ann Mullally, MD, Susumu S Kobayashi, MD PhD, Eduardo Magalhães Rego, MD PhD, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2018) 132 (Supplement 1): 4335.

https://doi.org/10.1182/blood-2018-99-115006

Published: 2018

Journal Articles

KMT2E-Mediated Epigenetic Reprogramming Promotes the Sensitivity to All-Trans Retinoic Acid and Increases the Granulocytic Differentiation in AML Cells

Luciana Yamamoto Almeida, PhD, Isabel Weinhäuser, MSc, Diego Antonio Pereira-Martins, MSc, Josiane Lilian Schiavinato, PhD, Patrícia Vianna Bonini Palma, BSc, Camila Bonaldo, Cleide Lucia Silva, MSc, Juliana Oliveira Poltronieri, MSc, Larissa Cândido, MSc, Antonio R. Lucena-Araujo, PhD, Eduardo Magalhães Rego, MD PhD

Blood (2018) 132 (Supplement 1): 3838.

https://doi.org/10.1182/blood-2018-99-118478

Published: 2018

Journal Articles

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

Izabela Aparecida Lopes, MSc, Miroslava Kardosova, MSc, Thiago Mantello Bianco, MSc, Adriana Queiroz Arantes, MD, Cleide Araújo Silva, MSc, Priscila Santos Scheucher, PhD, Daniel G. Tenen, MD, Sanghoon Lee, PhD, Eduardo Magalhães Rego, MD PhD, Robert S. Welner, PhD, Meritxell Alberich-Jorda, Lorena Lobo Figueiredo-Pontes, MD PhD

Blood (2018) 132 (Supplement 1): 3721.

https://doi.org/10.1182/blood-2018-99-119389

Published: 2018

Journal Articles

NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients

Virginia Mara De Deus Wagatsuma, PhD, Diego Antonio Pereira-Martins, MSc, Mariane Cristina Do Nascimento, BSc, Silvia Elena Sanchez Mendoza, Antonio R. Lucena-Araujo, PhD, Aleide Lima, MSc, Felipe Saldanha-Araujo, PhD, Fabio Pitella, PhD, Fabiola Traina, MD PhD, Maria Isabel A Madeira, MSc, MD, Lorena Lobo Figueiredo-Pontes, MD PhD, Eduardo Magalhães Rego, MD PhD

Blood (2018) 132 (Supplement 1): 5257.

https://doi.org/10.1182/blood-2018-99-119411

Published: 2018

Journal Articles

WHO-2016 Classification in ALL By Cytogenetics, FISH and Molecular Biology - Experience of Two Reference Centers in Brazil

Elvira DRP Velloso, MD PhD, Maria Gabriella Cordeiro, Danielle Lucon, PhD, Renata Kishimoto, Aline Medeiros Leal, PhD, Ana Carolina Arrais Maia, MD, Valeria Buccheri, MD PhD, Israel Bendit, MD PhD, Wellington Fernandes Silva, Jr., MD, Cristovao Mangueira, MD PhD, Eduardo Magalhães Rego, MD PhD, Vanderson Rocha, MD PhD

Blood (2018) 132 (Supplement 1): 5288.

https://doi.org/10.1182/blood-2018-99-115426

Published: 2018

Journal Articles

Acute Lymphocytic Leukemia in the Latin American Population

Elisa Quiroz, MD, Rebecca Nelson, Ibrahim Aldoss, MD, Vinod A. Pullarkat, MD, Thomas Slavin, MD, Guido Marcucci, Eduardo Magalhães Rego, MD PhD, Dan Douer, MD

Blood (2018) 132 (Supplement 1): 5282.

https://doi.org/10.1182/blood-2018-99-120079

Published: 2018

Journal Articles

Clinical Impact and Therapeutic Opportunity of Insulin Receptor Substrates 1/2 in Acute Myeloid Leukemia

Juan Luiz Coelho-Silva, BSc, MSc, Diego Antonio Pereira-Martins, MSc, Josiane Lilian Schiavinato, PhD, Eduardo Magalhães Rego, MD PhD, João Agostinho Machado-Neto, BSc, Fabiola Traina, MD PhD

Blood (2018) 132 (Supplement 1): 1512.

https://doi.org/10.1182/blood-2018-99-119156

Published: 2018

Journal Articles

Improving the Outcomes of Acute Promyelocytic Leukemia in a Limited Resources Setting: The Benefit of Early ATRA Administration in 30-Day Survival

Bruno Kosa Lino Duarte, MD, Ana Carolina Mourão Toreli, MD, Mariana Dos Santos Pastori, MD, Paulo Vittor Oliveira Peres, MD, Andreza Lamonica, MD, Camilla Maria de Alencar Saraiva, MD, Eduardo Magalhães Rego, MD PhD, Katia B Pagnano, MD

Blood (2018) 132 (Supplement 1): 5874.

https://doi.org/10.1182/blood-2018-99-119875

Published: 2018

Journal Articles

Clinical, Cytogenetic and Immunophenotype Distribution of Adult Acute Lymphoblastic Leukemia Among Latinos — a Report from a Large Single Institution Cohort in Southern California

Elisa Quiroz, MD, Rebecca Nelson, MD, Vinod A. Pullarkat, MD, Ibrahim Aldoss, Thomas Slavin, MD, Eduardo Magalhães Rego, MD PhD, Guido Marcucci, Dan Douer, MD

Blood (2018) 132 (Supplement 1): 2816.

https://doi.org/10.1182/blood-2018-99-119962

Published: 2018

Journal Articles

Impact of Treatment Free Remission (TFR) with Nilotinib in 2 nd Line for Chronic Myeloid Leukemia on Savings That May Fund All BCR-ABL Tests in the Brazilian Public Healthcare System during and after Nilotinib Treatment

Andre Abdo, MD, Carla Maria Boquimpani, MD, Douglas Vivona, PhD, Viviane Silveira Leite, BSC, Alisson L. Matsuo, PhD, Vanessa Teich, BSC, Israel Bendit, MD PhD, Eduardo Magalhães Rego, MD PhD, Vanderson Rocha, MD PhD

Blood (2018) 132 (Supplement 1): 4760.

https://doi.org/10.1182/blood-2018-99-119200

Published: 2018

Journal Articles

Pharmacological IRS1/2 Inhibition Induces Apoptosis in BCR-ABL1 T315I mutant Cells

Renata Scopim-Ribeiro, M.Sc., João Agostinho Machado-Neto, PhD, Christopher A. Eide, Paula de Melo Campos, PhD, Priscila Santos Scheucher, PhD, Sara Teresinha Olalla Saad, MD PhD, Eduardo Magalhães Rego, MD, PhD, Cristina E. Tognon, Brian J. Druker, MD, Fabiola Traina, MD, PhD

Blood (2016) 128 (22): 1886.

https://doi.org/10.1182/blood.V128.22.1886.1886

Published: 2016

Journal Articles

Multitarget Antileukemic Effects of Metformin in Myeloproliferative Neoplasm Cells: Inhibition of JAK2/STAT Signaling and Mitochondrial Activity

João Agostinho Machado-Neto, PhD, Bruna Alves Fenerich, B.Sc., Renata Scopim-Ribeiro, M.Sc., Carlos Roberto Porto Dechandt, B.Sc., Ana Paula Nunes Rodrigues Alves, M.Sc., Jaqueline Cristina Fernandes, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Luciane Carla Alberici, PhD, Lorena Lôbo de Figueiredo Pontes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD

Blood (2016) 128 (22): 1960.

https://doi.org/10.1182/blood.V128.22.1960.1960

Published: 2016

Journal Articles

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Virginia Mara De Deus Wagatsuma, PhD, Luisa C A Koury, MD, Silvia Elena Sánchez, MSc, Lorena Lobo Figueiredo Pontes, MD; PhD, Fernanda Borges da Silva, MSc, Adriana Ines Dore, Biologist, Ana Silvia Gouvêa de Lima, PhD, Antonio R. Lucena-Araujo, PhD, Luciana Yamamoto Almeida, PhD, Fabiola Traina, MD, PhD, Felipe Saldanha-Araújo, PhD, Fabio Pittella-Silva, PhD, Eduardo Magalhães Rego, MD, PhD

Blood (2016) 128 (22): 5097.

https://doi.org/10.1182/blood.V128.22.5097.5097

Published: 2016

Journal Articles

Pharmacological IGF1R/IRS Inhibitor, NT157, Effectively Induces Apoptosis and CDKN1A Expression in Acute Lymphoblastic Leukemia Cells

Ana Paula Nunes Rodrigues Alves, M.Sc., João Agostinho Machado-Neto, PhD, Jaqueline Cristina Fernandes, B.Sc., Bruna Alves Fenerich, B.Sc., Fernanda Borges da Silva, B.Sc., Priscila Santos Scheucher, PhD, Belinda Pinto Simões, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD

Blood (2016) 128 (22): 3971.

https://doi.org/10.1182/blood.V128.22.3971.3971

Published: 2016

Journal Articles

Association of Setmar Expression with Clinical Characteristics in Chronic Lymphocytic Leukemia

Flavia Z Piazera, MD, Doralina Amaral Rabello, Felipe Araújo Saldanha, Fábio Pitella Silva, Fábio Morato Oliveira, Antonio R. Lucena-Araujo, Eduardo Magalhães Rego, MD, PhD

Blood (2015) 126 (23): 4815.

https://doi.org/10.1182/blood.V126.23.4815.4815

Published: 2015

Journal Articles

The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in Higher Complete Hematological Remission Rates, but Does Not Prolong Overall Survival

Luisa C A Koury, Graduate Student, Lorena Lobo Figueiredo-Pontes, MD PhD, Belinda Pinto Simoes, MD, PhD, Luciana C O Oliveira, MD, Leandro F F Dalmazzo, MD, Maria Carolina Tostes Pintão, MD, Aglair B Garcia, Roberto Passetto Falcão, MD PhD, Eduardo Magalhães Rego, MD, PhD

Blood (2015) 126 (23): 4896.

https://doi.org/10.1182/blood.V126.23.4896.4896

Published: 2015

Journal Articles

Tissue Factor Pathway Inhibitor (TFPI) May be Another Important Factor in the Coagulopathy in Acute Promyelocytic Leukemia (APL)

Sarah C Bassi, MD, Eduardo Magalhães Rego, MD, PhD

Blood (2015) 126 (23): 2278.

https://doi.org/10.1182/blood.V126.23.2278.2278

Published: 2015

Journal Articles

Pharmacological IRS1/2 Inhibition Reduces Cell Viability in BCR-ABL1 Positive Cells

Renata Scopim-Ribeiro, M.Sc., João Agostinho Machado-Neto, PhD, Paula de Melo Campos, PhD, Adriana da Silva Santos Duarte, PhD, Priscila Santos Scheucher, PhD, Amélia Góes, PhD, Sara Teresinha Olalla Saad, MD, PhD, Belinda Pinto Simoes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD

Blood (2015) 126 (23): 2772.

https://doi.org/10.1182/blood.V126.23.2772.2772

Published: 2015

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Abnormal Distribution and Function of NK Cells Subsets May Lead to Impaired Tumor Surveillance in a JAK2V617F Myeloproliferative Neoplasm Model

KMT2E-Mediated Epigenetic Reprogramming Promotes the Sensitivity to All-Trans Retinoic Acid and Increases the Granulocytic Differentiation in AML Cells

C/Ebpg (CCAAT/Enhancer Binding Protein Gamma) Balances Cytotoxic and Secretory Potential of Natural Killer Cells

NSD1 and NSD2 Transcriptional Levels Might Predict Clinical Outcome in AML Patients

WHO-2016 Classification in ALL By Cytogenetics, FISH and Molecular Biology - Experience of Two Reference Centers in Brazil

Acute Lymphocytic Leukemia in the Latin American Population

Clinical Impact and Therapeutic Opportunity of Insulin Receptor Substrates 1/2 in Acute Myeloid Leukemia

Improving the Outcomes of Acute Promyelocytic Leukemia in a Limited Resources Setting: The Benefit of Early ATRA Administration in 30-Day Survival

Clinical, Cytogenetic and Immunophenotype Distribution of Adult Acute Lymphoblastic Leukemia Among Latinos — a Report from a Large Single Institution Cohort in Southern California

Impact of Treatment Free Remission (TFR) with Nilotinib in 2 nd Line for Chronic Myeloid Leukemia on Savings That May Fund All BCR-ABL Tests in the Brazilian Public Healthcare System during and after Nilotinib Treatment

Pharmacological IRS1/2 Inhibition Induces Apoptosis in BCR-ABL1 T315I mutant Cells

Multitarget Antileukemic Effects of Metformin in Myeloproliferative Neoplasm Cells: Inhibition of JAK2/STAT Signaling and Mitochondrial Activity

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Pharmacological IGF1R/IRS Inhibitor, NT157, Effectively Induces Apoptosis and CDKN1A Expression in Acute Lymphoblastic Leukemia Cells

Association of Setmar Expression with Clinical Characteristics in Chronic Lymphocytic Leukemia

The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in Higher Complete Hematological Remission Rates, but Does Not Prolong Overall Survival

Tissue Factor Pathway Inhibitor (TFPI) May be Another Important Factor in the Coagulopathy in Acute Promyelocytic Leukemia (APL)

Pharmacological IRS1/2 Inhibition Reduces Cell Viability in BCR-ABL1 Positive Cells

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