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Alice S. Mims, MD MSCR
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Journal Articles

Neurofibromin 1 gene Mutations Are Recurrent Events in Adult Patients with Acute Myeloid Leukemia (AML), Associate with Poor Outcome and Refine the Adverse European Leukemianet (ELN) Risk Category

Ann-Kathrin Eisfeld, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, Alice S. Mims, MD MSCR, Christopher J. Walker, PhD, James S. Blachly, MD, Deedra Nicolet, MS, Shelley Orwick, BS, Sofia E. Maharry, Andrew Carroll, PhD, Bayard L. Powell, MD, Jonathan E. Kolitz, MD, Eunice S. Wang, MD, Richard M. Stone, MD, Albert de la Chapelle, MD PhD, John C. Byrd, MD, Clara D. Bloomfield, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 186.
https://doi.org/10.1182/blood.V130.Suppl_1.186.186
Published: 2017
Journal Articles

OSU-2S, a Novel PKC Activator, Mediates PKC Dependent Cell Death, Differentiation and Cell Cycle Arrest in Acute Myeloid Leukemia

Swagata Goswami, MS, Rajeswaran Mani, DVM,PhD, Xiaokui Mo, PhD MAS, Pearlly S. Yan, PhD, Michael B Broe, PhD, Ralf Bundschuh, PhD, Larry State Beaver, Kevan Zapolnik, BS, Zhiliang Xie, Donna Bucci, David M. Lucas, PhD, Allison R. Walker, MD MPH, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Ching-Shih Chen, PhD, John C. Byrd, MD, Mitch A. Phelps, PhD, Sumithira Vasu, MDMBBS, Natarajan Muthusamy, DVM,PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1247.
https://doi.org/10.1182/blood.V130.Suppl_1.1247.1247
Published: 2017
Journal Articles

Transplant Associated Thrombotic Microangiopathy (TA-TMA) Commonly Occurs after Steroid-Refractory or Dependent Gastrointestinal (GI) Graft Versus Host Disease (GVHD) and Contributes to Post-Transplant Morbidity

Sarah A Wall, MD, Qiuhong Zhao, MS, Parvathi Ranganathan, PhD, Patrick Elder, Basem M. William, MD, Marcin Puto, PharmD, Julianna Roddy, PharmD, Rebecca B. Klisovic, MD, William Blum, MD, Don M Benson, Jr., MD PhD, Samantha Jaglowski, MD MPH, Alice S. Mims, MD MSCR, Jonathan E Brammer, MD, Yvonne A Efebera, MD, Craig C Hofmeister, MDMPH, Leslie Andritsos, MD, Sam Penza, MD, Allison R. Walker, MD MPH, Steven M. Devine, MD, Spero R Cataland, MD, Sumithira Vasu, MDMBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 4483.
https://doi.org/10.1182/blood.V130.Suppl_1.4483.4483
Published: 2017
Journal Articles

Ivosidenib (AG-120) in Mutant IDH1 AML and Advanced Hematologic Malignancies: Results of a Phase 1 Dose Escalation and Expansion Study

Courtney D. DiNardo, MDMSc, Stephane De Botton, Eytan M. Stein, MD, Gail J. Roboz, MD, Alice S. Mims, MD MSCR, Daniel A. Pollyea, MD, Ronan T. Swords, MD PhD FRCPI, FRCPath, Jessica K. Altman, MD, Robert H. Collins, MD, Gabriel N. Mannis, MD, Geoffrey L. Uy, MD, Will Donnellan, MD, Arnaud Pigneux, MD PhD, Amir T. Fathi, MD MD BS, Anthony S. Stein, MD, Harry P. Erba, MD PhD, Gabrielle T. Prince, MD, James M. Foran, MD, Elie Traer, MD PhD, Robert K. Stuart, MD, Martha L. Arellano, MD, James L. Slack, MD, Mikkael A. Sekeres, MD MS, Katharine Yen, Stephanie M. Kapsalis, Hua Liu, Meredith Goldwasser, Sam Agresta, MD, Eyal C. Attar, MD, Martin S. Tallman, MD, Richard M. Stone, MD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 725.
https://doi.org/10.1182/blood.V130.Suppl_1.725.725
Published: 2017
Journal Articles

Ivosidenib or Enasidenib Combined with Standard Induction Chemotherapy Is Well Tolerated and Active in Patients with Newly Diagnosed AML with an IDH1 or IDH2 Mutation: Initial Results from a Phase 1 Trial

Eytan M. Stein, MD, Courtney D. DiNardo, MDMSc, Alice S. Mims, MD MSCR, Michael R. Savona, MD, Keith Pratz, MD, Anthony S. Stein, MD, Amir T. Fathi, MD MD BS, Richard M. Stone, MD, Daniel A. Pollyea, MD, Olatoyosi Odenike, MD, Bob Lowenberg, MD PhD, Hartmut Döhner, MD, Gary J. Schiller, Ira V. Gupta, MD, Salah Nabhan, Vickie Zhang, PhD, Caroline Almon, MS, Michael Cooper, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 726.
https://doi.org/10.1182/blood.V130.Suppl_1.726.726
Published: 2017
Journal Articles

Xpert ® BCR-ABL Ultra, a High Sensitivity Assay, Demonstrates a Limit of Detection Reaching MR4.5 and below

Christophe Ferrand, PhD, Marina Deschamps, PhD, Alba Levitas, Christina Lockwood, PhD, Jacqueline E. Payton, MDPhD, Geoffrey L. Uy, MD, Charles A. Schiffer, MD, Gerald Feldman, MD, Aaron Bossler, MD PhD, Julie Woolworth, PhD, Alice S. Mims, MD MSCR, Krupa Shridhar, Natalie Wu, PhD, Sandy Huang, Huilin Wei, MD PhD, Chris Lykke, PhD, Michael P. Bates, MD, Wendy Wong, Gwo-Jen Day, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1610.
https://doi.org/10.1182/blood.V130.Suppl_1.1610.1610
Published: 2017
Journal Articles

Response Rates, Non-Relapse Mortality, and Financial Implications of Transplant-Associated Thrombotic Microangiopathy Treated with Eculizumab

John L Vaughn, MD, Qiuhong Zhao, MS, Parvathi Ranganathan, PhD, Patrick Elder, Basem M. William, MRCP,MD, Marcin Puto, PharmD, Julianna Roddy, PharmD, Rebecca Klisovic, William Blum, MD, Don M Benson, Jr., MD PhD, Samantha M. Jaglowski, MDMPH, Alice S. Mims, MD MSCR, Jonathan E. Brammer, MD, Bhavana Bhatnagar, DO, Yvonne A Efebera, MD, Craig C Hofmeister, MDMPH, Leslie A Andritsos, MD, Sam Penza, MD, Allison R. Walker, MD MPH, Steven M. Devine, MD, Spero R Cataland, MD, Sumithira Vasu, MDMBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 1932.
https://doi.org/10.1182/blood.V130.Suppl_1.1932.1932
Published: 2017
Journal Articles

The Novel BET Inhibitor PLX51107 Has In Vitro and In Vivo Activity Against Acute Myeloid Leukemia

Nicole R. Grieselhuber, MD PhD, Shaneice R. Mitchell, BS, Shelley Orwick, BS, Bonnie K. Harrington, DVM, Virginia M. Goettl, DVM, PhD, Alison R. Walker, MD MPH, Bhavana Bhatnagar, DO, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Sumithra Vasu, MBBS, William Blum, MD, James S. Blachly, MD, David M. Lucas, PhD, Ramiro Garzon, MD, Rosa Lapalombella, PhD, John C. Byrd, MD
Journal: Blood
Blood (2016) 128 (22): 3941.
https://doi.org/10.1182/blood.V128.22.3941.3941
Published: 2016
Journal Articles

CD33 Targeted Immunoliposomal Delivery of OSU-2S, a Non-Immunosuppressive FTY720 Derivative, Mediates Selective Cytotoxicity in Acute Myeloid Leukemia

Swagata Goswami, MS, Rajeswaran Mani, DVM PhD, Chi-Ling Chiang, MS, Frank W Frissora, M.S., Xiaokui Mo, PhD MAS, Zhiliang Xie, Donna Bucci, Amber Gordon, MLS, David M. Lucas, PhD, William Blum, MD, Alison R. Walker, MD MPH, Alice S. Mims, MD MSCR, Rebecca B Klisovic, MD, Ching-Shih Chen, PhD, Robert J Lee, PhD, John C. Byrd, MD, Mitch A. Phelps, PhD, Sumithira Vasu, MBBS, Natarajan Muthusamy, DVM, PhD
Journal: Blood
Blood (2016) 128 (22): 2748.
https://doi.org/10.1182/blood.V128.22.2748.2748
Published: 2016
Journal Articles

Interim Results of a Phase 1b/2 Study of Entospletinib (GS-9973) Monotherapy and in Combination with Chemotherapy in Patients with Acute Myeloid Leukemia

Alison R. Walker, MD MPH, Bhavana Bhatnagar, DO, A. Mario Q. Marcondes, MD, Julie DiPaolo, PhD, Sumithra Vasu, MBBS, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Katherine J. Walsh, MD, Renee Canning, RN, Gregory K. Behbehani, MD PhD, Ramiro Garzon, MD, James S. Blachly, MD, Amy J. Johnson, PhD, Esteban Abella-Dominicis, John C. Byrd, MD, William Blum, MD
Journal: Blood
Blood (2016) 128 (22): 2831.
https://doi.org/10.1182/blood.V128.22.2831.2831
Published: 2016
Journal Articles

A Phase 1 Clinical Trial of Selinexor in Combination with Decitabine in Patients with Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia

Bhavana Bhatnagar, DO, Rebecca B. Klisovic, MD, Alison R. Walker, MD MPH, Sumithra Vasu, MBBS, Alice S. Mims, MD MSCR, Katherine J. Walsh, MD, Gregory K. Behbehani, MD PhD, James S. Blachly, MD, Molly Vittorio, Qiuhong Zhao, Amy S. Ruppert, MAS, Shelley Orwick, BS, Parvathi Ranganathan, PhD, John C. Byrd, MD, William Blum, MD, Ramiro Garzon, MD
Journal: Blood
Blood (2016) 128 (22): 1651.
https://doi.org/10.1182/blood.V128.22.1651.1651
Published: 2016
Journal Articles

Determination of IDH1 Mutational Burden and Clearance Via Next-Generation Sequencing in Patients with IDH1 Mutation-Positive Hematologic Malignancies Receiving AG-120, a First-in-Class Inhibitor of Mutant IDH1

Courtney D DiNardo, MD, Stéphane de Botton, Eytan M Stein, Gail J. Roboz, Ronan T Swords, MD PhD FRCPI, FRCPath, Daniel A Pollyea, MD, Amir T. Fathi, MD, Robert Collins, Jessica K Altman, Ian W. Flinn, MD PhD, Gabriel N Mannis, Alice S. Mims, MD MSCR, James M. Foran, MD, Arnaud Pigneux, MD, Gabrielle T Prince, MD, Geoffrey L Uy, MD, Martin S. Tallman, MD, Hagop M. Kantarjian, MD, Hua Liu, Eyal C Attar, Jennifer Sacolick, Katharine Yen, Jonathan B Hurov, Sung Choe, Bin Wu, Richard M. Stone, MD
Journal: Blood
Blood (2016) 128 (22): 1070.
https://doi.org/10.1182/blood.V128.22.1070.1070
Published: 2016
Journal Articles

A Novel Regimen for Acute Myeloid Leukemia with MLL Partial Tandem Duplication: Results of a Phase 1 Study NCI 8485

Alice S. Mims, MD MSCR, Rebecca B Klisovic, MD, Ramiro Garzon, MD, Alison R. Walker, MD MPH, Steven M. Devine, MD, Katherine J. Walsh, MD, Sumithira Vasu, MBBS, Susan P. Whitman, PhD, Guido Marcucci, MD, Nyla A. Heerema, PhD, Michael A. Caligiuri, MD, Clara D. Bloomfield, MD, John C. Byrd, MD, Richard Piekarz, PhD MD, Michael R. Grever, MD, William Blum, MD
Journal: Blood
Blood (2016) 128 (22): 900.
https://doi.org/10.1182/blood.V128.22.900.900
Published: 2016
Journal Articles

CX-01, a Low Anticoagulant Heparin, May Enhance Count Recovery and Treatment Efficacy in Acute Myeloid Leukemia

Tibor J. Kovacsovics, MD, Alice S. Mims, MD MSCR, Mohamed E Salama, MD, Jeremy M Pantin, MD, Ken M Kosak, B.S., Narayanam Rao, PhD, Peter Ahorukomeye, Martha Glenn, MD, Michael W. Deininger, MD PhD, Kenneth M Boucher, PhD, Linda M Bavisotto, MD, Gerardo Gutierrez-Sanchez, PhD, Thomas P Kennedy, MD MPH, Stephen Garrett Marcus, MD, Paul J Shami, MD
Journal: Blood
Blood (2016) 128 (22): 5220.
https://doi.org/10.1182/blood.V128.22.5220.5220
Published: 2016