We observed diabetes mellitus (DM) in 9.3% of adults with sickle cell disease (SCD) and DM predicted a 7-fold greater risk for chronic kidney disease progression adjusting for high-risk APOL1. Our results emphasize the clinical significance of DM in SCD.

Subjects:
Red Cells, Iron, and Erythropoiesis
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2025

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First page of Diabetes Mellitus and APOL1 Genotype Increase the Risk for Chronic Kidney Disease Progression in Sickle Cell Disease
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