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First Edition

Research Article April 25 2025
Targeting HASPIN kinase disrupts SR protein-mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML
Mengdan Liu,Ming Yan,Amanda G. Davis,Samuel A. Stoner,Edward D. Ball,Dong-Er Zhang
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Research Article April 25 2025
The oral CDK9 inhibitor voruciclib combined with venetoclax in patients with relapsed/refractory acute myeloid leukemia
Yesid Alvarado-Valero,Rachel J. Cook,Shira N. Dinner,Michael Keng,Kebede H. Begna,Nathalie Javidi-Sharifi,Sameem Abedin,Monzr M. Al Malki,Vijaya Raj Bhatt,Prabhu Rajagopalan,Min Tang,Sandra E. Wiley,Richard G. Ghalie,Matthew S. Davids
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Research Article April 25 2025
Checkpoint immunotherapy is associated with preferential activation of tumor-antigen specific CD4+ T cells in MDS.
Elizabeth A. Griffiths,Pragya Srivastava,Eduardo Cortes Gomez,Junko Matsuzaki,Kunle Odunsi,Laura W. Dillon,Devdeep Mukherjee,Christopher S. Hourigan,Jacqueline Peng,Shovik Bandyopadhyay,Kai Tan,Kristopher M. Attwood,Joseph B. Kuechle,Prashant K. Singh,Jianmin Wang,Michael J. Nemeth
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Research Article April 25 2025
Activity of STAMP inhibitors in ABL2 rearranged Acute Lymphoblastic Leukemia is dependent on the Abl2 SH3 domain
Elias Lagonik,Elyse C. Page,John B. Bruning,Laura N. Eadie,Susan L. Heatley,Matthew Greenwood,Chun Y. Fong,Andrew S. Moore,David T. Yeung,Timothy P. Hughes,Deborah L. White
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Research Article April 16 2025
Olfactory Receptors as Tumor Suppressors in Cutaneous T-Cell Lymphoma via p38γ Pathway Modulation
Xu Hannah Zhang,Hongzhi Li,Jack Hsiang,Ching-Hong Chen,Sangkil Nam,Henry Wong,Xiwei Wu,Weidong Hu,Jack Shively,Steven T. Rosen
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Research Article April 16 2025
Outcomes of Myeloablative Allogeneic Hematopoietic Cell Transplantation with Omidubicel vs Haploidentical and Unrelated Donor Sources
Chenyu Lin,Smitha Sivaraman,Gautam Sajeev,Yan Song,Chunyi Xu,Chujun He,James E. Signorovitch,Heayoung Shin,Xiao-Ying Tang,Mei-Jie Zhang,Linda J. Burns,Ronit Simantov,Mitchell E. Horwitz
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Research Article April 16 2025
Outcomes at a Single Institution with MTR Induction and Consolidation in the Management of Primary CNS Lymphoma
Nikita K. Dave,Veronica Carvajal,Alex C. Watts,Jordan S. Carter,Michael Cook,Colin Thomas,Donald E. Tsai,Stephen J. Schuster,James N. Gerson,Stefan K. Barta,Jakub Svoboda,Elise A. Chong,Wei-Ting Hwang,Daniel J. Landsburg,Sunita D. Nasta
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Research Article April 16 2025
Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma: a Real-World Experience
Malin Hultcrantz,Andriy Derkach,Hani Hassoun,Neha Korde,Kylee MacLachlan,Sham Mailankody,Dhwani Patel,Urvi A Shah,Carlyn R Tan,David J Chung,Oscar B Lahoud,Heather Landau,Michael Scordo,Gunjan L Shah,David Nemirovsky,Ross S Firestone,Theresia Akhlaghi,Tala Shekarkhand,Sergio Giralt,Alexander M Lesokhin,Saad Z Usmani
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Brief Report April 15 2025
Magnetic resonance spectroscopy-based detection of response to therapy targeting glutaminolysis in lymphoma
Kavindra Nath,Pradeep K Gupta,Shengchun Wang,Alexander A Shestov,Neil Sen,Shilpa Rao,Stepan Orlovskiy,Cosimo Lobello,David Rushmore,Fernando Arias-Mendoza,Johnvesly Basappa,David S Nelson,Mariusz A. Wasik
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Research Article April 4 2025
A novel cereblon variant with both exon 8 and 10 deletions in newly diagnosed and relapsed multiple myeloma
Yuan Xiao Zhu,Soumya Dutta,Gregory J. Ahmann,Laura Bruins,Mariano Arribas,Xianfeng Chen,Abhigna Polikarpov,Jonathan Chapman,Issac Lopez,Marta Chesi,P. Leif Bergsagel,Abhishek Singharoy,Rafael Fonseca,Lisa M. Rimsza
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Research Article April 3 2025
Quality of life, fatigue, depression, attention deficits and pain after childhood Langerhans cell histiocytosis
Malin Sveijer,Désirée Gavhed,Helena Hertzberg,Eric Zander,Jan-Inge Henter,Tatiana von Bahr Greenwood
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Research Article April 3 2025
Ambroxol induces myeloma cell death by inhibiting autophagy
Yutaka Hattori,Hiromu Sugiyama,Yamato Miyashita,Shinsuke Shibata,Taiga Okaue,Yoshinao Matsumoto,Taketo Yamada,Tomofumi Yamamoto,Takashi Yamaguchi,Kohei Yamazaki,Hisako Kunieda,Hideyuki Saya,Maiko Matsushita
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Brief Report April 3 2025
Risk Factors and Clinical Impact of Cytomegalovirus DNAemia in patients with Multiple Myeloma Treated with Teclistamab
Charles Pei,Zeinab El Boghdadly,Lisa Blackburn,Nidhi Sharma,Naresh Bumma,Abdullah M. Khan,Srinivas Devarakonda,Elvira Umyarova,Don Benson,Ashley Rosko,Francesca Cottini
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Brief Report April 3 2025
Reduced CD20 Expression yields Inferior Survival in Patients with B Cell Lymphoma Treated with CD20xCD3 Antibodies
Emil Ramsø Kyvsgaard,Trine Lønbo Grantzau,Mia Dahl Sørensen,Michael Boe Møller,Lene Sjø,Morten Grauslund,Trine Trab,Linea Cecilie Melchior,Lærke Sloth Andersen,Caroline Riley,Carsten U. Niemann,Jacob Haaber,Thomas Stauffer Larsen,Michael Roost Clausen,Kirsten Grønbæk,Martin Hutchings,Simon Husby
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Research Article March 21 2025
Tumor-associated myeloid cells support murine T-ALL in the central nervous system via integrin signaling
Ryan S. Humphrey,Seohee Nam,Dennis C. Wylie,Lauren I. R. Ehrlich
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Research Article March 11 2025
Discovery of a novel class NSD2 inhibitor for t(4;14)-positive multiple myeloma
Sae Matsuoka,Naoki Osada,Hirokazu Kubota,Ko Kikuzato,Hiroo Koyama,Takeshi Sonoda,Akiko Idei,Minoru Yoshida,Masaki Kikuchi,Takashi Umehara,Chiduru Watanabe,Teruki Honma,Hiroshi Yasui,Sho Ikeda,Naoto Takahashi,Hideki Nakasone,Jiro Kikuchi,Yusuke Furukawa
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Research Article March 10 2025
Retrospective Evaluation of R-EPOCH in the Frontline Treatment of Adult PTLD Patients Following Solid Organ Transplant
Brian Cuzzo,Maegan Ford,Saagar Jain,Hua-Jay Cherng,Evelyn Orlando,Patrick Gould,Amy Song,Benjamin May,Yuxuan Chen,Govind Bhagat,Andrew H. Lipsky,Barbara Pro,Jennifer E. Amengual
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Review Article March 10 2025
Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation
Hannah Kunstek,Janneke Kieviet,Caroline Lindemans,Coco de Koning,Stefan Nierkens
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Brief Report March 10 2025
Genomic Landscape and Clonal Architecture in Pediatric Myeloid Neoplasms with Chromosome 7 Deletions
Tamara Westover,Michael P. Walsh,Sherif Abdelhamed,Emily Xiong,Jing Ma,Guangchun Song,Melvin Thomas,Masayuki Umeda,Jamie L. Maciaszek,Jasmine C. Wong,Astrid Wintering,Lu Wang,Peter D. Emanuel,Mignon L. Loh,Sarah K. Tasian,Elliot Stieglitz,Jason R. Schwartz,Kevin M. Shannon,Jeffery M. Klco
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Brief Report March 6 2025
Response and Outcomes of Patients with IDH1/2 Mutated Accelerated/Blast-Phase Myeloproliferative Neoplasms
Leah A. Goldberg,James J. Yoon,Hannah Johnston,Marta B. Davidson,Alexa Siddon,Rory M. Shallis,Evan C. Chen,Madelyn Burkart,Timothy S. Oh,Sunil G. Iyer,Ellen Madarang,Chandrasekar Muthiah,Joshua Kassner,Raajit K. Rampal,Guru Subramanian Guru Murthy,Terrence Bradley,Yasmin Abaza,Jacqueline S. Garcia,Vikas Gupta,Kristen M. Pettit,Olatoyosi Odenike,John F. Cursio,Anand A. Patel
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Research Article March 3 2025
Phase 1 Trial of Venetoclax with Cladribine, Cytarabine, G-CSF, and Mitoxantrone for AML and High-Grade Myeloid Neoplasm
Suravi Raychaudhuri,Ted A. Gooley,Allegra Rasmussen,Kim Quach,Eva Gill,Anna B. Halpern,Jacob S. Appelbaum,Cristina M. Ghiuzeli,Paul C. Hendrie,Ryan D. Cassaday,Roland B. Walter,Mary-Elizabeth M. Percival
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Research Article March 3 2025
Phase 2 trial of daratumumab, cyclophosphamide, thalidomide and dexamethasone in newly diagnosed multiple myeloma
Edvan de Queiroz Crusoe,Joanna Suzana Leal Ribeiro dos Santos,Juliana de Andrade Santos,Herbert Henrique de Melo Santos,Allan de Souza Santos,Larissa Ferreira Lucas,Cristiane Almeida Requião de Pinna,Paula Nogueira Caldas Freire,Adriano Araujo de Jesus,Alessandro de Moura Almeida,Daniela Dourado Dutra,Marcos Fonseca Chaves,Jamile Souza Nicanor,Marco Aurelio Salvino,Maria da Gloria Bomfim Arruda,Vania Hungria,on behalf of GBRAM
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Research Article March 3 2025
TYK2 is essential for the therapeutic effect of IFN-α in Jak2V617F-induced murine myeloproliferative neoplasms
Yuki Tahira,Kotaro Shide,Takuro Kameda,Taisuke Uchida,Ayako Kamiunten,Keiichi Akizuki,Yoko Kubuki,Masayoshi Karasawa,Ryoma Ikeda,Kengo Matsumoto,Jie Bai,Minoru Terashima,Koji Kato,Tomofumi Uto,Tomohiro Fukaya,Shuya Mitoma,Katsuaki Sato,Yudai Uehira,Hiroaki Ueno,Goro Sashida,Hideki Yamaguchi,Kazuya Shimoda
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Research Article January 16 2025
Clarithromycin, Ixazomib, Pomalidomide, Dexamethasone for Relapsed/Refractory Myeloma: Survival and Correlative Analysis
Aaron S Rosenberg,Emanual Maverakis,Caitlin Costello,Elizabeth A. Brem,Matthew Joseph Wieduwilt,Guillaume Luxardi,Paul Kaesberg,Keon Abedi,Samantha Herbert,Joseph Tuscano
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