Figure 1.
Figure 1. Cytotoxicity assay. Bone marrow mononuclear cells from 8 patients treated with CEP-701 were incubated in vitro (in cell culture medium) with increasing concentrations of CEP-701. Each drug concentration point was performed in triplicate. At 72 hours, metabolic activity was determined using the MTT assay. Results are plotted for each sample as percentage (optical density [OD]) of untreated control. Error bars represent SE.

Cytotoxicity assay. Bone marrow mononuclear cells from 8 patients treated with CEP-701 were incubated in vitro (in cell culture medium) with increasing concentrations of CEP-701. Each drug concentration point was performed in triplicate. At 72 hours, metabolic activity was determined using the MTT assay. Results are plotted for each sample as percentage (optical density [OD]) of untreated control. Error bars represent SE.

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