Disease-free survival according to treatment arms. (A) DFS of the 344 patients in whom complete remission was obtained, depending on initial randomization (without quinine, n = 171; with quinine, n = 173). (B) DFS of the 262 patients who were assigned to intensive consolidation therapy, without or with quinine according to initial randomization (without quinine, n = 134; with quinine, n = 128).