Fig. 9.
SOCS-2 overexpression slows cell growth and sensitizes cells to STI571-induced death.
(A) Protein extracts from 107 cells were separated on a 12% SDS-PAGE gel and stained for SOCS-2 and actin. (B) 2.5 × 104 cells/mL were seeded in tissue culture flasks with or without 1 μM STI571. Cell proliferation (top panel) and viability (bottom panel) were assessed by trypan blue staining. Cultures were fed every 48 hours as required.
