Fig. 2.
Effect of a fibrinogen receptor antagonist on ADP-induced generation of thromboxane A2.
Washed human platelets were activated with ADP (10 μM) plus fibrinogen at 37°C with stirring in the presence or absence of varying doses of SC49992, a fibrinogen receptor antagonist. Reaction in the absence of SC49992 is used as a control. Thromboxane B2was measured as described in Figure 1. The data are derived from at least 3 independent experiments in duplicate and analyzed as in Figure 1.
