Fig. 1.
Binding of total and free HCV to human cell lines and platelets.
Molt-4 or U937 cells (1 × 105) or platelets (1 × 106) were incubated with untreated or IgG-depleted plasma samples from HCV-infected patients S7 (A) or Af (B). The amount of HCV added to the incubations was adjusted to 5.7 × 103 and 6.7 × 104 IU for S7 and Af samples, respectively. The extent of viral binding to the target cells was determined by quantitative real-time RT-PCR analysis. The exact amounts of HCV (IU) bound are shown at the top of each column. Data are means of triplicates from a representative experiment.