TRAIL-induced apoptosis is delayed in

CASP2L/AS-transfected cells. Apoptosis induced by 100 (Jurkat) to 200 (CEM) ng/mL recombinant TRAIL was quantified by staining nuclear chromatin with Hoechst 33342 in Jurkat/neo (▪), Jurkat/AS1 (▨), CEM/neo (▪), and CEM/AS (▨). Results are the mean ± SD of 3 independent experiments.