IVS of CMV⁺ volunteers with 3 analog peptides.

Aliquots of magnetically depleted lymphocytes were incubated with autologous APCs loaded with one of 3 amidated analog peptides or the native sequence under IVS conditions as described in the legend to Figure 1 and in “Materials and methods.” Either peptide-loaded autologous (black and stippled bars) or HLA-mismatched (gray and white bars) EBVLCLs (A) or autologous (black and stippled bars) or HLA-mismatched (gray and white bars) CMV-infected fibroblasts (B) were used as targets as described in the legend to Figure 1 and in “Materials and methods.” E/T ratios were 25 (black and gray bars) and 5 (stippled and white bars) for panel A and 50 (black and gray bars) and 10 (stippled and white bars) for panel B.