Fig. 8.
Fig. 8. KF58333 treatment decreased the expression level of Cdk4 and Cdk6. / K562 cells were cultured with indicated concentration of KF58333 for 48 hours or 0.1 μmol/L of KF58333 for the indicated time and analyzed as described in “Materials and methods.” Total cell lysates were subjected to Western blotting with anti-Cdk2 antibody (A), anti-Cdk4 antibody (B,E), anti-Cdk6 antibody (C), and anti-p27Kip1antibody (D,F).

KF58333 treatment decreased the expression level of Cdk4 and Cdk6.

K562 cells were cultured with indicated concentration of KF58333 for 48 hours or 0.1 μmol/L of KF58333 for the indicated time and analyzed as described in “Materials and methods.” Total cell lysates were subjected to Western blotting with anti-Cdk2 antibody (A), anti-Cdk4 antibody (B,E), anti-Cdk6 antibody (C), and anti-p27Kip1antibody (D,F).

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