Location of point mutations in RPS19 gene. The position of single nucleotide substitutions or small deletions or insertions in RPS19 gene found in DBA patients is indicated along the structure of the gene. Nucleotide and amino acid numbers are shown at start of exons and at the end of exons. Nucleotide numbers start from the ATG of the gene. Data include results from the present study, as well as mutations described in an earlier report.25 Larger deletions or translocations are not shown in this figure.