Analysis of the TCR repertoire expressed by T cells at sites of DTH skin tests with autologous Id. CDR3 size distribution patterns at the level of BV-BC transcripts from a representative MM (UPN 14) are shown. (X-axis) Sizes in amino acids of the CDR3 regions. (Y-axis) Fluorescence intensities, reflecting the number of clones using each CDR3 size combination. The high frequency of abnormal patterns (ie, CDR3 profiles without a Gaussian-like distribution) is indicative of the presence of multiple clonal T-cell populations.