Longitudinal follow-up of KS/HIV-1 patients for IgG antibody to HHV-8. Patient no. 1 (•) was diagnosed with KS a month after the last serum sample and died a month after diagnosis. On autopsy, KS was found in his internal organs. Patient no. 2 (▪) was diagnosed with KS between his fourth and fifth samples. Patient no. 3 (▴) was diagnosed with KS before the first sample. Patient no. 4 (▾) was a seroconverter, his first sample had no HHV-8 IgG titer, but all of his subsequent samples did; he was diagnosed with KS between his third and fourth serum samples. Vertical line represents diagnosis of KS. See text for more details.