The nm1054 phenotype. (A) Two nm/nm (left) and 2 ?/+ (right) pups on postnatal day of life 4 (P4). The mutants are easily recognizable by their runting and pallor. (B) A nm/nm animal at P19 in the foreground and a wild-type (?/+) littermate in the background. Runting, abnormal fur, and hydrocephalus are evident in the mutant. (C-D) Peripheral blood smears from adult ?/+ and nm/nm animals, respectively. Hypochromia, microcytosis, anisocytosis, polychromasia, and target cells are prominent features in the mutant smear.