Nonsynonymous mutations in TP53 are significantly enriched in population of patients with confirmed TP53 deletion. (A) Presence of TP53 mutations was examined in delTP53 patients from MGP data set (n = 108) stratified by CCF value >0.55 or <0.55. Kaplan-Meier plots were generated for OS (B) and PFS (C) for patients with TP53 mutation (mut) with CCF >0.55 (red line), patients with wild-type (wt) TP53 with CCF ≤0.55 (blue line), and patients with TP53wt with CCF >0.55 (green line). *One-sided Fisher’s exact test.