Kinetics of Flt3L response during induction. Sequential patients with weekly measurement of Flt3L during induction chemotherapy (n = 12; 4 in cohort A and 8 in cohort B). Dotted line indicates the timing of a single Flt3L measurement in patients treated on the AML17 trial. (A) Weekly Flt3L in 6 patients entering CR following induction chemotherapy (B) Weekly Flt3L in 4 patients with refractory disease or partial response following induction chemotherapy. (C) Weekly Flt3L in 2 patients rendered aplastic by induction chemotherapy