Effect of hypoxia on CP LTCICs and CP cells with engraftment capacity. CML cells were treated for 4 days under the specified conditions before being subjected to (a) Limiting dilution LTCIC (samples CML#1 and CML#2) and (b) NSG engraftment assays (sample CML#3). Each point represents data from one mouse. Horizontal bars indicate mean. *p<0.05.