Figure 1.
Figure 1. Results from the CHARM analysis on AML patients stratified by cytogenetic risk, highlighting comparison between the high-risk and other risk groups. The top twelve differentially methylated regions ( DMRs) with p -value < 0.01 are shown. Box-and-whisker plots to the left of the dashed vertical line in each panel present the log2 methylation ratio of the high-risk group and the other two risk groups combined, in a single region of differential methylation. To the right of the dashed line the high-risk group is compared with each of the other groups. Each panel's header text identifies the genomic region.

Results from the CHARM analysis on AML patients stratified by cytogenetic risk, highlighting comparison between the high-risk and other risk groups. The top twelve differentially methylated regions ( DMRs) with p -value < 0.01 are shown. Box-and-whisker plots to the left of the dashed vertical line in each panel present the log2 methylation ratio of the high-risk group and the other two risk groups combined, in a single region of differential methylation. To the right of the dashed line the high-risk group is compared with each of the other groups. Each panel's header text identifies the genomic region.

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