CHD7 regulates RUNX1/CBFβ and RUNX1/CBFβ-SMMHC transactivation activity. (A) Luciferase reporter assay in 293T cells transfected with a CSF1R promoter-driven luciferase reporter plasmid and plasmids encoding the indicated proteins. Relative activities (mean ± SEM) were determined on the basis of 3 independent experiments. (B) Representative expression levels of the transfected proteins for this reporter assay. *P < .05.