Relationship between expression levels of ROR1 and TFS, OS on CLL cells segregated on the basis of IGHV mutation status. Kaplan-Meier curves depict the TFS (A) or OS (B) probability over time for ROR1-Lo with M-IGHV (black solid line), ROR1-Lo with U-IGHV (black dashed line), ROR1-Hi with M-IGHV (gray solid line), or ROR1-Hi with U-IGHV (gray dashed line) subgroups of all CLL patients for whom the IGHV mutation status is known.