Distribution, response rates, and duration of response according to BCR-ABL1 mutation status at baseline as determined by SS or NGS. (A) Percentage of patients with no mutation (0), one mutation (1), or 2 or more mutations (≥2) at baseline, as determined by SS or NGS. Also shown are subsets of these groups (separated by a dotted line) that had LL mutations only, or compound mutations, as determined by NGS. (B) MCyR rates, (C) MMR rates, and (D) Kaplan-Meier curves indicating the duration of continuous MCyR, according to baseline mutation status. The median follow-up after achievement of MCyR was 27.4 months, with the majority of patients (>80%) remaining in follow-up. BL, baseline; C, compound; LL, low-level; MCyR, major cytogenetic response; MMR, major molecular response.