Figure 1
![Figure 1. Histology and somatic mutations of histiocytoses of group L, C, R, M, and H. (A) L group: Histology of LCH (skin [i-ii] and bone [iii]) and of ECD (perirenal [iv-v]). Pie chart of relative frequencies of activating kinase mutations in LCH (vi) and ECD (vii). (B) C group: Histology of JXG (i-ii). (C) R group: Histology of RDD (meningeal with high IgG4+ plasma cell infiltration [i-ii]). (D) M group: Histology of MH (i-ii). (E) H group: Histology of inherited HLH (liver [i-ii]). Staining with CD1a (Lii in red), IgG4 (Rii in brown), CD163 (Hii in brown), or hematoxylin and eosin (all others). NOS, not otherwise specified.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/127/22/10.1182_blood-2016-01-690636/4/2672f1.jpeg?Expires=1753166232&Signature=r2FRfD-LYM9AUYZxqoeUok2y5k1EiXBX1qI7pQ-IkMdRztUbIaA3CZCjd90Zj9d353OIdVA~0NWeownhRrN~xdTtmRGiKS9jpPluh5UeLbWRT50vlPAHwmg7rz1txBdudF5RRHdjpep0K1Vs1I2e5y~ndum4rW-qPzGjMJ3WWviJDSjXJrEikDfilCeAr4loWlqlaxskseJL4NpaWJcjtZMe-0YccezmPex8m4alyzM9DxyR2AZ2vMKSdRpzuteMQIB2e95-Yc7y2QXFXAWKXM~Nfrq4mSurc~H7m-yaBuFYTkLf3syND3ewnv-nRlYXSyLiACNn-je4gnug17Vz9g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Histology and somatic mutations of histiocytoses of group L, C, R, M, and H. (A) L group: Histology of LCH (skin [i-ii] and bone [iii]) and of ECD (perirenal [iv-v]). Pie chart of relative frequencies of activating kinase mutations in LCH (vi) and ECD (vii). (B) C group: Histology of JXG (i-ii). (C) R group: Histology of RDD (meningeal with high IgG4+ plasma cell infiltration [i-ii]). (D) M group: Histology of MH (i-ii). (E) H group: Histology of inherited HLH (liver [i-ii]). Staining with CD1a (Lii in red), IgG4 (Rii in brown), CD163 (Hii in brown), or hematoxylin and eosin (all others). NOS, not otherwise specified.
