No significant difference in BS for type 1 VWD subjects regardless of VWF:Ag level. This graph shows the number of subjects with abnormal BS (defined as >2 in children <18 years of age, >3 in adult males, and >5 in adult females) in dark gray as compared with those with normal BS (light gray) for the entire type 1 VWD cohort by VWF:Ag. The percent of each group with abnormal BS is shown at the top of each column. BS were similar for type 1 subjects regardless of VWF:Ag.