hTERT-siTCR–transduced CD8⁺ T cells kill freshly isolated autologous ATL tumor cells on the basis of hTERT expression levels. Cytotoxic activity of hTERT-siTCR–transduced CD8⁺ T cells obtained from HLA-A*24:02⁺ ATL patients (n = 3) against autologous freshly isolated ATL tumor cells and autologous peripheral CD14⁺ cells (negative control) was tested in ⁵¹Cr-release assays at the indicated E/T ratios. hTERT mRNA in each patient’s ATL tumor cells is listed using a format similar to that used in Figure 5. Error bars represent SDs (* indicates less than detectable).